Activation of xenobiotic receptors: driving into the nucleus

Nuclear Translocation of Adenoviral-Enhanced Yellow Fluorescent Protein-Tagged-Human Constitutive Androstane Receptor (hCAR): A Novel Tool for Screening hCAR Activators in Human Primary Hepatocytes

(2009) H. Li et al.   DRUG METABOLISM AND DISPOSITION

A Systematic Analysis of Predicted Phosphorylation Sites within the Human Pregnane X Receptor Protein

(2009) K. Lichti-Kaiser et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A Single Amino Acid Controls the Functional Switch of Human Constitutive Androstane Receptor (CAR) 1 to the Xenobiotic-Sensitive Splicing Variant CAR3

(2009) T. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspects

(2009) Alessandra di Masi et al.   MOLECULAR ASPECTS OF MEDICINE

Di(2-ethylhexyl) phthalate Is a Highly Potent Agonist for the Human Constitutive Androstane Receptor Splice Variant CAR2

(2009) J. G. DeKeyser et al.   MOLECULAR PHARMACOLOGY

Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes

(2009) Niresh Hariparsad et al.   NUCLEIC ACIDS RESEARCH

Elucidating the ‘Jekyll and Hyde’ Nature of PXR: The Case for Discovering Antagonists or Allosteric Antagonists

(2009) Arunima Biswas et al.   PHARMACEUTICAL RESEARCH

Introducing the “TCDD-Inducible AhR-Nrf2 Gene Battery”

(2009) Ronnie L. Yeager et al.   TOXICOLOGICAL SCIENCES

PXR and CAR in energy metabolism

(2009) Taira Wada et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Aryl hydrocarbon receptor-mediated regulation of the human estrogen and bile acid UDP-glucuronosyltransferase 1A3 gene

(2008) Tim O. Lankisch et al.   ARCHIVES OF TOXICOLOGY

Discovery of substituted sulfonamides and thiazolidin-4-one derivatives as agonists of human constitutive androstane receptor

(2008) Jenni Küblbeck et al.   BIOCHEMICAL PHARMACOLOGY

Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR)

(2008) Bhaskar C. Das et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Nrf2 Activator Oltipraz Also Activates the Constitutive Androstane Receptor

(2008) M. D. Merrell et al.   DRUG METABOLISM AND DISPOSITION

Structural Basis of Human Pregnane X Receptor Activation by the Hops Constituent Colupulone

(2008) D. G. Teotico et al.   MOLECULAR PHARMACOLOGY

The Peripheral Benzodiazepine Receptor Ligand 1-(2-Chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide Is a Novel Antagonist of Human Constitutive Androstane Receptor

(2008) L. Li et al.   MOLECULAR PHARMACOLOGY

PPP1R16A, The Membrane Subunit of Protein Phosphatase 1 , Signals Nuclear Translocation of the Nuclear Receptor Constitutive Active/Androstane Receptor

(2008) T. Sueyoshi et al.   MOLECULAR PHARMACOLOGY

Perfluorocarboxylic Acids Induce Cytochrome P450 Enzymes in Mouse Liver through Activation of PPAR-α and CAR Transcription Factors

(2008) Xingguo Cheng et al.   TOXICOLOGICAL SCIENCES

Genetic variability of aryl hydrocarbon receptor (AhR)-mediated regulation of the human UDP glucuronosyltransferase (UGT) 1A4 gene

(2008) Thomas J. Erichsen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Active Nuclear Receptors Exhibit Highly Correlated AF-2 Domain Motions

(2008) Denise G. Teotico et al.   PLoS Computational Biology

The Phytoestrogen Coumestrol Is a Naturally Occurring Antagonist of the Human Pregnane X Receptor

(2007) Hongwei Wang et al.   MOLECULAR ENDOCRINOLOGY