GlycoFi's technology to control the glycosylation of recombinant therapeutic proteins

European Medicines Agency workshop on biosimilar monoclonal antibodies

(2010) Janice M. Reichert et al.   mAbs

Simple high-cell density fed-batch technique for high-level recombinant protein production with Pichia pastoris: Application to intracellular production of Hepatitis B surface antigen

(2009) Chandrasekhar Gurramkonda et al.   Microbial Cell Factories

Microbial factories for recombinant pharmaceuticals

(2009) Neus Ferrer-Miralles et al.   Microbial Cell Factories

Merck joins the biotech game

(2009) Victor Bethencourt   NATURE BIOTECHNOLOGY

A European perspective on immunogenicity evaluation

(2009) Christian K Schneider et al.   NATURE BIOTECHNOLOGY

Genome sequence of the recombinant protein production host Pichia pastoris

(2009) Kristof De Schutter et al.   NATURE BIOTECHNOLOGY

Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology

(2009) Pieter P Jacobs et al.   Nature Protocols

Gearing up for follow-on biologics

(2009) Bethan Hughes   NATURE REVIEWS DRUG DISCOVERY

Glycosylation as a strategy to improve antibody-based therapeutics

(2009) Roy Jefferis   NATURE REVIEWS DRUG DISCOVERY

Optimization of chemically defined medium for recombinant Pichia pastoris for biomass production

(2008) A. Ghosalkar et al.   BIORESOURCE TECHNOLOGY

Pichia Power: India's Biotech Industry Puts Unconventional Yeast to Work

(2008) Chandra Shekhar   CHEMISTRY & BIOLOGY

Editorial [Hot Topic: Therapeutic Antibodies and Derivatives: From the Bench to the Clinic(Guest Editor: Alain Beck)]

(2008) A. Beck et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Development and Production of Commercial Therapeutic Monoclonal Antibodies in Mammalian Cell Expression Systems: An Overview of the Current Upstream Technologies

(2008) Michel Chartrain et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Monoclonal Antibodies as Innovative Therapeutics

(2008) Janice Reichert   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Trends in Glycosylation, Glycoanalysis and Glycoengineering of Therapeutic Antibodies and Fc-Fusion Proteins

(2008) Alain Beck et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Ecallantide (DX-88), a plasma kallikrein inhibitor for the treatment of hereditary angioedema and the prevention of blood loss in on-pump cardiothoracic surgery

(2008) Andreas Lehmann   EXPERT OPINION ON BIOLOGICAL THERAPY

Recombinant human lactoferrin expressed in glycoengineered Pichia pastoris: effect of terminal N-acetylneuraminic acid on in vitro secondary humoral immune response

(2008) Byung-Kwon Choi et al.   GLYCOCONJUGATE JOURNAL

Production of monoclonal antibodies by glycoengineered Pichia pastoris

(2008) Thomas I. Potgieter et al.   JOURNAL OF BIOTECHNOLOGY

The way forward, enhanced characterization of therapeutic antibody glycosylation: Comparison of three level mass spectrometry-based strategies

(2008) Elsa Wagner-Rousset et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Toward biosimilar monoclonal antibodies

(2008) Christian K Schneider et al.   NATURE BIOTECHNOLOGY

Use of high-performance anion exchange chromatography with pulsed amperometric detection for O-glycan determination in yeast

(2008) Terrance A Stadheim et al.   Nature Protocols

Economic issues with follow-on protein products

(2008) Michael Lanthier et al.   NATURE REVIEWS DRUG DISCOVERY

Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose

(2008) Christine H. Chung et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc

(2008) R. M. Anthony et al.   SCIENCE

The N-Linked sugar chains of human immunoglobulin G: Their unique pattern, and their functional roles

(2007) Akira Kobata   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Synthesis and characterization of a functional intact IgG in a prokaryotic cell-free expression system

(2007) Stephan Frey et al.   BIOLOGICAL CHEMISTRY

Characterization of a complex glycoprotein whose variable metabolic clearance in humans is dependent on terminal N-acetylglucosamine content

(2007) Rodney Keck et al.   BIOLOGICALS

Effect of constant and variable domain glycosylation on pharmacokinetics of therapeutic antibodies in mice

(2007) Thomas A. Millward et al.   BIOLOGICALS

Glycosylation of Recombinant Antibody Therapeutics

(2005) Royston Jefferis   BIOTECHNOLOGY PROGRESS