Microenvironmental pH-modification to improve dissolution behavior and oral absorption for drugs with pH-dependent solubility

Drug Disease Interactions: Role of Inflammatory Mediators in Pain and Variability in Analgesic Drug Response

(2016) Kenneth M. Kulmatycki et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Improved dissolution and pharmacokinetic behavior of dipyridamole formulation with microenvironmental pH-modifier under hypochlorhydria

(2012) Satomi Onoue et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Novel formulations of dipyridamole with microenvironmental pH-modifiers for improved dissolution and bioavailability under hypochlorhydria

(2012) Chika Taniguchi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Enhancing and Sustaining AMG 009 Dissolution from a Bilayer Oral Solid Dosage Form via Microenvironmental pH Modulation and Supersaturation

(2011) Mingda Bi et al.   AAPS PHARMSCITECH

Enhancing and Sustaining AMG 009 Dissolution from a Matrix Tablet Via Microenvironmental pH Modulation and Supersaturation

(2011) Mingda Bi et al.   AAPS PHARMSCITECH

Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications

(2011) Yohei Kawabata et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Preparation and in vitro–in vivo evaluation of none gastric resident dipyridamole (DIP) sustained-release pellets with enhanced bioavailability

(2011) Lishuang Xu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Using Absorption Simulation and Gastric pH Modulated Dog Model for Formulation Development To Overcome Achlorhydria Effect

(2011) Amitava Mitra et al.   MOLECULAR PHARMACEUTICS

Enhanced Solubility and Bioavailability of Sibutramine Base by Solid Dispersion System with Aqueous Medium

(2010) Dong Xun Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

pH modulation: a mechanism to obtain pH-independent drug release

(2010) Pallavi Bassi et al.   Expert Opinion on Drug Delivery

Dissolution-modulating mechanism of pH modifiers in solid dispersion containing weakly acidic or basic drugs with poor water solubility

(2010) Phuong Ha-Lien Tran et al.   Expert Opinion on Drug Delivery

Review: physical chemistry of solid dispersions

(2010) Sandrien Janssens et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Citric acid as a pH-modifying additive in an extended release pellet formulation containing a weakly basic drug

(2009) Jan Ploen et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?

(2009) Joachim Brouwers et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Systematic review:Heliocobacter pyloriinfection and impaired drug absorption

(2008) E. LAHNER et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Strategies to Overcome pH-Dependent Solubility of Weakly Basic Drugs by Using Different Types of Alginates

(2008) S. Gutsche et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Assessment of Tailor-Made HPMC-Based Matrix Minitablets Comprising a Weakly Basic Drug Compound

(2008) Stefanie Siepe et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Citric acid monohydrate as a release-modifying agent in melt extruded matrix tablets

(2008) Sandra U. Schilling et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Mechanisms of drug release in citrate buffered HPMC matrices

(2008) Samuel R. Pygall et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Measurement of Surface pH of Pharmaceutical Solids: A Critical Evaluation of Indicator Dye-Sorption Method and its Comparison With Slurry pH Method

(2007) Madhu Pudipeddi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES