Various drug delivery approaches to the central nervous system

Intranasal Insulin Administration Dose-Dependently Modulates Verbal Memory and Plasma Amyloid-β in Memory-Impaired Older Adults

(2017) Mark A. Reger et al.   JOURNAL OF ALZHEIMERS DISEASE

Delivery of sodium borocaptate to glioma cells using immunoliposome conjugated with anti-EGFR antibodies by ZZ-His

(2009) Bin Feng et al.   BIOMATERIALS

Convection-enhanced delivery of nanocarriers for the treatment of brain tumors

(2009) Emilie Allard et al.   BIOMATERIALS

Recent Advances in Medicinal Chemistry and Pharmaceutical Technology- Strategies for Drug Delivery to the Brain

(2009) Nunzio Denora et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The potential for nanoparticle-based drug delivery to the brain: overcoming the blood–brain barrier

(2009) Eugen Barbu et al.   Expert Opinion on Drug Delivery

Challenges and opportunities in CNS delivery of therapeutics for neurodegenerative diseases

(2009) Thomas M Barchet et al.   Expert Opinion on Drug Delivery

Intranasal Deferoxamine Provides Increased Brain Exposure and Significant Protection in Rat Ischemic Stroke

(2009) L. R. Hanson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Dual-Targeting Topotecan Liposomes Modified with Tamoxifen and Wheat Germ Agglutinin Significantly Improve Drug Transport across the Blood−Brain Barrier and Survival of Brain Tumor-Bearing Animals

(2009) Ju Du et al.   MOLECULAR PHARMACEUTICS

Convection-enhanced delivery in the treatment of epilepsy

(2009) Michael A. Rogawski   Neurotherapeutics

Delivery of peptide and protein drugs over the blood–brain barrier

(2009) Ivona Brasnjevic et al.   PROGRESS IN NEUROBIOLOGY

Prodrug Approaches for CNS Delivery

(2008) Jarkko Rautio et al.   AAPS Journal

Polymeric micelles anchored with TAT for delivery of antibiotics across the blood-brain barrier

(2008) Lihong Liu et al.   BIOPOLYMERS

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

(2008) Leah R Hanson et al.   BMC NEUROSCIENCE

Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease

(2008) Barnabas Wilson et al.   BRAIN RESEARCH

188Re-loaded lipid nanocapsules as a promising radiopharmaceutical carrier for internal radiotherapy of malignant gliomas

(2008) E. Allard et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Preparation of estradiol chitosan nanoparticles for improving nasal absorption and brain targeting

(2008) Xiaomei Wang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Biofunctionalized targeted nanoparticles for therapeutic applications

(2008) Andrew Z Wang et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Polymeric nanoparticles for the drug delivery to the central nervous system

(2008) Giovanni Tosi et al.   Expert Opinion on Drug Delivery

Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26

(2008) Zhiqing Pang et al.   JOURNAL OF CONTROLLED RELEASE

Liposome encapsulated polyethylenimine/ODN polyplexes for brain targeting

(2008) Young Tag Ko et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticles of cationic chimeric peptide and sodium polyacrylate exhibit striking antinociception activity at lower dose

(2008) Kshitij Gupta et al.   JOURNAL OF CONTROLLED RELEASE

Transferrin-conjugated liposomal system for improved delivery of 5-fluorouracil to brain

(2008) Vandana Soni et al.   JOURNAL OF DRUG TARGETING

HER2-Specific Affibody-Conjugated Thermosensitive Liposomes (Affisomes) for Improved Delivery of Anticancer Agents

(2008) Anu Puri et al.   JOURNAL OF LIPOSOME RESEARCH

Design, Synthesis and Biological Evaluation of Glutathione Peptidomimetics as Components of Anti-Parkinson Prodrugs

(2008) Swati S. More et al.   JOURNAL OF MEDICINAL CHEMISTRY

Large Neutral Amino Acid Transporter Enables Brain Drug Delivery via Prodrugs

(2008) Mikko Gynther et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tumor-specific targeting of sodium borocaptate (BSH) to malignant glioma by transferrin-PEG liposomes: a modality for boron neutron capture therapy

(2008) Atsushi Doi et al.   JOURNAL OF NEURO-ONCOLOGY

Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats

(2008) L. Goldberg et al.   MOLECULAR CANCER THERAPEUTICS

Methotrexate Loaded Polyether-Copolyester Dendrimers for the Treatment of Gliomas: Enhanced Efficacy and Intratumoral Transport Capability

(2008) Renu Singh Dhanikula et al.   MOLECULAR PHARMACEUTICS

Progress in Drug Delivery to the Central Nervous System by the Prodrug Approach

(2008) Barbara Pavan et al.   MOLECULES

Convection-enhanced delivery of maghemite nanoparticles: Increased efficacy and MRI monitoring

(2008) Benny Perlstein et al.   NEURO-ONCOLOGY

Direct CNS Delivery of siRNA Mediates Robust Silencing in Oligodendrocytes

(2008) William Querbes et al.   OLIGONUCLEOTIDES

Development of a Smart Nano-vehicle to Target Cerebrovascular Amyloid Deposits and Brain Parenchymal Plaques Observed in Alzheimer’s Disease and Cerebral Amyloid Angiopathy

(2008) Edward K. Agyare et al.   PHARMACEUTICAL RESEARCH

Flurbiprofen Derivatives in Alzheimer’s Disease: Synthesis, Pharmacokinetic and Biological Assessment of Lipoamino Acid Prodrugs

(2007) Rosario Pignatello et al.   BIOCONJUGATE CHEMISTRY

Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG–TAT for drug delivery across the blood–brain barrier

(2007) Lihong Liu et al.   BIOMATERIALS

Progesterone for the treatment of experimental brain injury; a systematic review

(2007) C. L. Gibson et al.   BRAIN

Brain targeting using novel lipid nanovectors

(2007) Arnaud Béduneau et al.   JOURNAL OF CONTROLLED RELEASE