Gene therapy for pulmonary hypertension: prospects and challenges

Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy

(2010) Hossein A. Ghofrani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors

(2010) R. Alba et al.   BLOOD

Prognosis of Pulmonary Arterial Hypertension

(2010) Vallerie V. McLaughlin et al.   CIRCULATION

Predicting Survival in Pulmonary Arterial Hypertension

(2010) Raymond L. Benza et al.   CIRCULATION

Survival in Patients With Idiopathic, Familial, and Anorexigen-Associated Pulmonary Arterial Hypertension in the Modern Management Era

(2010) Marc Humbert et al.   CIRCULATION

BMP signaling in vascular development and disease

(2010) Jonathan W. Lowery et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study

(2010) H. A. Ghofrani et al.   EUROPEAN RESPIRATORY JOURNAL

Role of apoptosis in pulmonary hypertension: From experimental models to clinical trials

(2010) Paul Jurasz et al.   PHARMACOLOGY & THERAPEUTICS

Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats

(2009) Kiyoko Takemiya et al.   BASIC RESEARCH IN CARDIOLOGY

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

(2009) R. Alba et al.   BLOOD

Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension

(2009) Lu Long et al.   CIRCULATION

Autologous transplantation of bone marrow–derived endothelial progenitor cells attenuates monocrotaline-induced pulmonary arterial hypertension in rats

(2009) Hon-Kan Yip et al.   CRITICAL CARE MEDICINE

TGF-β and BMPR-II pharmacology—implications for pulmonary vascular diseases

(2009) Paul D Upton et al.   CURRENT OPINION IN PHARMACOLOGY

Cell therapy approaches for lung diseases: current status

(2009) Viranuj Sueblinvong et al.   CURRENT OPINION IN PHARMACOLOGY

Insertional mutagenesis and development of malignancies induced by integrating gene delivery systems: Implications for the design of safer gene-based interventions in patients

(2009) G. Romano et al.   DRUG NEWS & PERSPECTIVES

VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats

(2009) Laszlo Farkas et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetics and Genomics of Pulmonary Arterial Hypertension

(2009) Rajiv D. Machado et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Updated Evidence-Based Treatment Algorithm in Pulmonary Arterial Hypertension

(2009) Robyn J. Barst et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Diagnosis and Assessment of Pulmonary Arterial Hypertension

(2009) David B. Badesch et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Updated Clinical Classification of Pulmonary Hypertension

(2009) Gérald Simonneau et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Intratracheal Gene Transfer of Adrenomedullin Using Polyplex Nanomicelles Attenuates Monocrotaline-induced Pulmonary Hypertension in Rats

(2009) Mariko Harada-Shiba et al.   MOLECULAR THERAPY

Pathology of Pulmonary Arterial Hypertension

(2009) Rubin Tuder   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Cystic fibrosis gene therapy: successes, failures and hopes for the future

(2009) Uta Griesenbach et al.   Expert Review of Respiratory Medicine

Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions

(2008) James West et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Clinical Outcomes of Pulmonary Arterial Hypertension in Carriers ofBMPR2Mutation

(2008) Benjamin Sztrymf et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

(2008) Simon N. Waddington et al.   CELL

Genetic Ablation of the Bmpr2 Gene in Pulmonary Endothelium Is Sufficient to Predispose to Pulmonary Arterial Hypertension

(2008) Kwon-Ho Hong et al.   CIRCULATION

Progress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors

(2008) N Brunetti-Pierri et al.   GENE THERAPY

Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature

(2007) David B. Frank et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Gene Transfer of Extracellular Superoxide Dismutase Ameliorates Pulmonary Hypertension in Rats

(2007) Fumihiko Kamezaki et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE