期刊
EXPERIMENTAL PARASITOLOGY
卷 119, 期 4, 页码 524-533出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.exppara.2008.04.013
关键词
E. granulosus; protoscolex; cellular territories
类别
资金
- FONDECYT-CHILE [1010817, 1050135]
- Grant DID
- University of Chile [1013-99/2]
Basic aspects of the generation, structure and function of Echinococcus granulosus protoscoleces are unknown. We review the work done on the structure and ultrastructure of the E. granulosus protoscolex and provide new data together with a comprehensive view of this form of the parasite. The surface, as observed by scanning electron microscopy, tightly correlates with five cellular territories characterized in the interior using light and transmission electron microscopy as well as a histochemical technique. Three of these territories are surrounded by a basal lamina that is also present in the internal side of the tegument, suggesting a complex internal organization. These cellular territories correlate with the expression of specific genes and the regionalization of DNA synthesis in protoscoleces. Additionally, a proposal to explain movements of the body of this form of the parasite in relation to the neck or to the germinal layer of the hydatid cyst is provided. (C) 2008 Elsevier Inc. All rights reserved.
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