Editorial Material
Business
Madeleine Rauch, Moritz Loock, Wolfgang H. Guettel
Summary: This introduction examines the relationship between heuristics, technological forecasting, and social change. It introduces five articles included in the Special Issue on 'Heuristics in Technological Forecasting and Social Change' and proposes directions for further research. The authors highlight important, yet unexplored research questions that could enhance the study of heuristics in the context of social and technological change.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2023)
Editorial Material
Computer Science, Hardware & Architecture
Jean-Pierre Hamaide, Christian Lerminiaux, Philippe Chanclou, Pierre Sillard
Summary: This special issue includes extensions of tutorials and invited and top-scored optical networking papers that were presented at the European Conference on Optical Communication (ECOC) 2021, held 13-16 September 2021 in Bordeaux, France.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2022)
Editorial Material
Engineering, Electrical & Electronic
Ilko Ilev, David Nolte, Qiyin Fang, Giuliano Scarcelli, Yuji Matsuura, William Calhoun, Thomas Huser
Summary: Biophotonics is an emerging and rapidly growing field of advanced biomedical technologies that encompasses a wide range of applications, from laboratory research to clinical diagnostics, bioimaging, biosensing, and therapeutics.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2021)
Editorial Material
Computer Science, Hardware & Architecture
Ramon Casellas, Raul Munoz, Marija Furdek, Salvatore Spadaro, Zuqing Zhu
Summary: This special issue of JOCN includes extended versions of selected papers presented at the 24th International Conference on Optical Network Design and Modeling (ONDM2020), covering current trends in optical networking research such as filterless optical networks, programmable transceivers, and machine learning applications in networks.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2021)
Article
Education & Educational Research
Francis John Troyan, Jose David Herazo, Marianna Ryshina-Pankova
Summary: The theory and educational practices of systemic functional linguistics (SFL) aim to facilitate learners in constructing meanings across linguistic and cultural contexts, providing a theoretical basis and practical methods for second language education. SFL pedagogies are designed to develop students' abilities to understand and convey meanings in different communicative contexts.
Editorial Material
Computer Science, Hardware & Architecture
Marija Furdek, Paolo Monti, Carmen Mas Machuca, Jaroslaw Turkiewicz, David Larrabeiti
Summary: This special issue of JOCN features extended versions of selected papers from the 25th International Conference on Optical Network Design and Modeling. The papers cover various trends in optical networking research, including capacity upgrade, spectral efficiency improvement, novel network architectures, and inter-operator sharing of optical network capacity.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2022)
Editorial Material
Computer Science, Hardware & Architecture
Jaroslaw Piotr Turkiewicz, Teresa Gomes, Miroslaw Klinkowski, Jacek Rak, Massimo Tornatore
Summary: This JOCN special issue features extended versions of selected papers from the 26th International Conference on Optical Network Design and Modeling (ONDM 2022), held at Warsaw University of Technology, Warsaw, Poland from 16th to 19th May 2022. The papers cover trends in optical networking research, including the application of machine learning to network management, cross-layer network performance optimization, visible light communication, and coherent metro networks.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2023)
Editorial Material
Computer Science, Hardware & Architecture
Jane M. Simmons
Summary: This special issue features extensions of invited and top-scored optical networking papers from the OFC Conference 2020, providing an overview of the major topics covered in the papers.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2021)
Editorial Material
Computer Science, Hardware & Architecture
Laurent Schares, Andrew Lord
Summary: This special issue features extended versions of selected optical networking papers from the OFC Conference in San Diego, California, which took place from 6-10 March 2022. An overview of the major topics covered in the papers is provided.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2023)
Editorial Material
Computer Science, Hardware & Architecture
Peter Van Daele, Ton Koonen, Johan Bauwelinck, Oded Raz
Summary: This special issue includes extended versions of invited and top-scored optical networking papers presented at the European Conference on Optical Communication (ECOC) 2020, which was held virtually from December 6-10, 2020.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2021)
Article
Mathematics
Ivan Marin
Summary: The study focuses on a quotient of the group algebra of the braid group with Artin generators satisfying a cubic relation, as well as proper quotients in the realm of quantum groups and another maximal quotient related to Hecke algebras. The connection between this algebra and a quotient of the algebra of horizontal chord diagrams introduced by Vogel is described, with the isomorphism of the two proven for n < 5.
JOURNAL OF ALGEBRA
(2022)
Editorial Material
Computer Science, Hardware & Architecture
Sayan Ghosh, Ryan E. Grant, Min Si
Summary: This article provides an introductory editorial for this issue of the publication.
Editorial Material
Computer Science, Hardware & Architecture
Makoto Ikeda, Fumio Arakawa
Summary: This article presents three significant contributions from Cool Chips 24 conference: acceleration of convolutional neural networks (CNN), training of mobile deep neural networks (DNN), and a supercomputer. These research papers were written by authors from China, Korea, and Japan, respectively, and they all focus on emerging topics at Cool Chips 24.
Editorial Material
Engineering, Electrical & Electronic
Qiyin Fang, Charles Kervrann, David Nolte, Oxana Semyachkina-Glushkovskaya, Shuo Tang, Yuji Matsuura, Zachary Smith
Summary: Biophotonics is an interdisciplinary field that combines photonics and biomedical applications. It has made significant advancements in clinical diagnosis, therapeutics, biotechnology, and environmental studies. The integration of optics and biology has led to quick adoption of photonics technologies in medicine due to its compatibility with minimally invasive procedures.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2023)
Editorial Material
Engineering, Electrical & Electronic
Jose Capmany, Christina Lim, Kazutosi Kato, Patrick Runge, Andreas Beling
Summary: The papers in this special section focus on optical detectors and the conversion from photons to electrons, which is a crucial operation in photonic systems. The development in the past five decades, especially based on heterostructures, quantum wells, and uni-carrier operation, has yielded impressive results in terms of bandwidth, noise, and footprint.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2022)
Article
Microbiology
Peter Kuhnert, Isabelle Brodard, Sabine Bock, Andrew Hemphill, Hatice Akarsu, Andreas Engelhardt, Peter Kutzer
Summary: Seven bacterial strains isolated from bovine endocarditis were classified into a new genus within the family Neisseriaceae, distinct from established genera. Whole genome sequence analysis and MALDI-TOF MS spectra analysis were effective methods for identification.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2022)
Article
Parasitology
Yang Zheng, Joachim Mueller, Stefan Kunz, Marco Siderius, Louis Maes, Guy Caljon, Norbert Mueller, Andrew Hemphill, Geert Jan Sterk, Rob Leurs
Summary: By combining structural elements of phosphodiesterase inhibitors with a nitroimidazole scaffold, the study aimed to improve antiparasitic efficacy by generating nitrosative stress.
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
(2022)
Article
Immunology
Azadeh Nasuhidehnavi, Yanlin Zhao, Ankita Punetha, Andrew Hemphill, Hong Li, Tyler J. Bechtel, Theresa Rager, Bingcong Xiong, Vasileios Petrou, Marc-Jan Gubbels, Eranthie Weerapana, George S. Yap
Summary: The host cell surface receptor, basigin, and its related immunoglobulin family members play an important role in mediating the attachment of Toxoplasma gondii to host cells.
INFECTION AND IMMUNITY
(2022)
Article
Veterinary Sciences
Dennis Imhof, William Robert Pownall, Carling Schlange, Camille Monney, Luis-Miguel Ortega-Mora, Kayode K. Ojo, Wesley C. Van Voorhis, Anna Oevermann, Andrew Hemphill
Summary: This study investigated the safety and efficacy of a combined vaccination-drug treatment approach in a pregnant neosporosis mouse model. The results showed that the combination treatment was more effective in reducing infection and improving pup survival compared to vaccination or drug treatment alone. Further evaluation is recommended.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Veterinary Sciences
Sheena Chaudhry, Raphael Zurbriggen, Matias Preza, Tobias Kampfer, Marc Kaethner, Roman Memedovski, Nathalie Scorrano, Andrew Hemphill, Joseph Stone Doggett, Britta Lundstrom-Stadelmann
Summary: Alveolar echinococcosis, caused by the zoonotic parasite Echinococcus multilocularis, could potentially be treated through a novel approach targeting the mitochondrial energy metabolism of the parasite, specifically the oxidative phosphorylation and the anaerobic malate dismutation pathways.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Oksana Desiatkina, Ghalia Boubaker, Nicoleta Anghel, Yosra Amdouni, Andrew Hemphill, Julien Furrer, Emilia Paunescu
Summary: This study reports the synthesis, photophysical properties, and antiparasitic efficacy of a series of 15 new conjugates that are fluorescent markers against Toxoplasma gondii beta-gal. The influence of different bond types and lengths on fluorescence and biological activity was evaluated. The compounds show limited antiparasitic activity but potential as fluorescent probes.
Article
Multidisciplinary Sciences
Kai Pascal Alexander Haenggeli, Andrew Hemphill, Norbert Mueller, Bernd Schimanski, Philipp Olias, Joachim Mueller, Ghalia Boubaker
Summary: In this study, single and duplex TaqMan qPCR methods were developed for the absolute quantification of integrated drug selectable marker mdhfr-ts in Toxoplasma gondii. The single TaqMan qPCR method should have twice the copy number of dhfr-ts as compared to WT parasites in KO parasites. The duplex TaqMan qPCR method can simultaneously amplify the dhfr-ts fragment and the 529-bp repeat element in T. gondii for accurate detection of KOs.
Article
Multidisciplinary Sciences
Alireza Badirzadeh, Mehdi Najm, Andrew Hemphill, Maryam Alipour, Hamid Hasanpour, Leila Masoori, Poorya Karimi
Summary: This study investigated the effect of negative air ions (NAIs) therapy on Leishmania parasites in vitro and in a murine model. The results showed that NAIs therapy significantly decreased the viability of Leishmania parasites and reduced footpad lesion size and parasite burden in infected mice. Additionally, NAIs therapy boosted immune responses and reduced the induction of IL-4 and arginase activity, while increasing IFN-gamma and NO levels. However, NAIs therapy was less effective than amphotericin B treatment.
Article
Biochemistry & Molecular Biology
Joachim Mueller, Ghalia Boubaker, Dennis Imhof, Kai Haenggeli, Noe Haudenschild, Anne-Christine Uldry, Sophie Braga-Lagache, Manfred Heller, Luis-Miguel Ortega-Mora, Andrew Hemphill
Summary: Leucinostatins are antimicrobial peptides that have a broad range of activities. In this study, a derivative peptide called 6027 was tested for its activity against Toxoplasma gondii, a parasitic organism. While effective in vitro, the application of peptide 6027 in mice infected with T. gondii worsened the infection. Peptide 6027 also affected the viability of mouse splenocytes. Through differential affinity chromatography and mass spectrometry, common targets for peptide 6027 were identified in both T. gondii and mouse spleen extracts. This method can be a useful way to identify drug targets in pathogens and hosts.
Article
Immunology
Monireh Khordadmehr, Alireza Sazmand, Pardis Almasi, Parisa Shahbazi, Vahidreza Ranjbar, Domenico Otranto, Andrew Hemphill
Summary: This study provides an overview of the prevalence and exposure to tissue cyst-forming apicomplexan parasites in Iranian domestic rock pigeons through molecular, serological, and histopathological examination. The results demonstrate that pigeons in Iran are infected, particularly with T. gondii, and suggest the need for control strategies to minimize the risk of infection in both pigeons and humans.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2023)
Article
Biochemistry & Molecular Biology
Oksana Desiatkina, Martin Moesching, Nicoleta Anghel, Ghalia Boubaker, Yosra Amdouni, Andrew Hemphill, Julien Furrer, Emilia Paunescu
Summary: A library of nucleobase-tethered trithiolato-bridged dinuclear ruthenium(II)-arene conjugates was synthesized and evaluated for their anti-Toxoplasma activity. Two promising compounds were identified, which exhibited low toxicity against host cells and have potential as treatment options.
Article
Biochemistry & Molecular Biology
Isabelle Holzer, Oksana Desiatkina, Nicoleta Anghel, Serena K. K. Johns, Ghalia Boubaker, Andrew Hemphill, Julien Furrer, Emilia Paunescu
Summary: Eight novel carbohydrate-tethered trithiolato dinuclear ruthenium(II)-arene complexes were synthesized and evaluated for their activity against transgenic T. gondii tachyzoites. Seven conjugates strongly inhibited parasite proliferation while maintaining HFF viability. Two galactose-based conjugates (23 and 26) exhibited low IC50 values and reduced toxicity compared to the non-modified complexes.
Article
Immunology
Dennis Imhof, William Pownall, Kai Pascal Alexander Hanggeli, Camille Monney, Laura Rico-San Roman, Luis-Miguel Ortega-Mora, Franck Forterre, Anna Oevermann, Andrew Hemphill
Summary: In this study, a modified version of the attenuated Listeria monocytogenes vaccine vector Lm3Dx_NcSAG1 was tested for its efficacy in a pregnant neosporosis mouse model. Multivalent vaccines were generated by inserting gra7 and/or rop2 genes into Lm3Dx_NcSAG1. Immunization with Lm3Dx_NcSAG1 and Lm3Dx_NcSAG1_NcGRA7_NcROP2 resulted in the highest postnatal pup survival rate and protection against vertical transmission and CNS infection.
Article
Biochemistry & Molecular Biology
Kai Pascal Alexander Hanggeli, Andrew Hemphill, Norbert Muller, Manfred Heller, Anne-Christine Uldry, Sophie Braga-Lagache, Joachim Muller, Ghalia Boubaker
Summary: Gene knock-out using CRISPR-Cas9 is a useful tool to identify gene functions in T. gondii and other model organisms. Previous studies have shown that knocking out a gene can also affect the expression of other genes. Therefore, caution should be taken when studying the relationship between specific phenotypes and the knock-out of a particular gene.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Parasitology
Joachim Mueller, Carling Schlange, Manfred Heller, Anne-Christine Uldry, Sophie Braga-Lagache, Richard K. Haynes, Andrew Hemphill
Summary: Artemisinin and its amino-artemisinin derivatives are potent antimalarials and exhibit different mechanisms of action against Plasmodium and T. gondii. The amino-artemisinins are effective in vitro against non-heme-degrading apicomplexan parasites including T. gondii. However, T. gondii strains readily adapt to increased concentrations of these compounds, resulting in the development of resistant strains.
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
(2023)
