期刊
EXPERIMENTAL GERONTOLOGY
卷 47, 期 10, 页码 759-763出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.exger.2012.06.010
关键词
Genetics; Nematodes; Fertility; Demography; Longevity; Evolutionary theory; Antagonistic pleiotropy
资金
- NIH [PO1-AG08761]
- Glenn Foundation
- Ellison Medical Research Foundation
Evolutionary theories of aging suggest that trade-offs between longevity and fitness should be found under certain conditions. In C. elegans, there is little evidence for the existence of such trade-offs. We asked if fertility/longevity trade-offs exist in populations of randomly mating males and hermaphrodites. We set up a large population of young males and 5-day-old hermaphrodites that were no longer self-fertile. We then allowed themto mate for one day with an equal number young males and then separated hermaphrodites to individual plates and determined daily fertility of individual hermaphrodites. There was a significant negative relationship between late-life fertility and individual longevity. (c) 2012 Elsevier Inc. All rights reserved.
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