Review
Biochemistry & Molecular Biology
Christopher Hubner, Hajo Haase
Summary: Zinc and ROS play roles in various physiological functions and are connected through their interaction with sulfur, forming a triad. Zinc can translate redox signals into zinc signals by binding to and releasing from thiols, affecting thiol oxidation and protein activity. The reciprocal interaction between zinc and redox-signaling involves shared molecular targets like active site cysteine thiols in PTP, showcasing their complex interplay on multiple levels.
Review
Cell Biology
F. Timoteo-Ferreira, D. Abreu, S. Mendes, L. Matos, A. R. Rodrigues, H. Almeida, E. Silva
Summary: The age of women having their first child is increasing, posing a major health challenge to society. Advanced maternal age is associated with decreased fertility, pregnancy complications, and offspring health issues. Ovarian aging, due to a decline in follicle number and oocyte quality, is a key contributor to female reproductive decline.
AGEING RESEARCH REVIEWS
(2021)
Article
Biochemistry & Molecular Biology
Larissa A. C. Carvalho, Rodrigo G. Queijo, Alexandre L. B. Baccaro, Adamo D. D. Siena, Wilson A. Silva Jr, Tiago Rodrigues, Silvya Stuchi Maria-Engler
Summary: Melanoma, the most aggressive type of skin cancer, is influenced by redox imbalance and redox proteins may serve as biomarkers and potential targets. Understanding genetic alterations and protein expression in melanoma patients can provide clues for new therapies.
Article
Biochemistry & Molecular Biology
Paulo H. C. Mesquita, Donald A. Lamb, Joshua S. Godwin, Shelby C. Osburn, Bradley A. Ruple, Johnathon H. Moore, Christopher G. Vann, Kevin W. Huggins, Andrew D. Fruge, Kaelin C. Young, Andreas N. Kavazis, Michael D. Roberts
Summary: The study found that 6 weeks of resistance training reduced oxidative damage and increased antioxidant enzyme activities in skeletal muscle of older adults. The responses of older adults to resistance training involve multi-level control (transcriptional, post-transcriptional, and post-translational) of the redox status of skeletal muscle.
Article
Medicine, General & Internal
Ana R. Soares de Oliveira, Kyria Jayanne Climaco Cruz, Jennifer Beatriz Silva Morais, Loanne Rocha Dos Santos, Stefany Rodrigues de Sousa Melo, Larissa C. Fontenelle, Gustavo Santos de Sousa, Carla Soraya Costa Maia, Camilla Oliveira Duarte de Araujo, Islanne Leal Mendes, Gilberto Simeone Henriques, Vladimir Costa Silva, Dilina do Nascimento Marreiro
Summary: This study found that obese women have selenium deficiency and increased oxidative stress levels. There is a significant association between adiposity indices and selenium status, as well as between erythrocyte selenium concentration and erythrocyte glutathione peroxidase activity.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2021)
Review
Biochemistry & Molecular Biology
Ursula Abou-Rjeileh, G. Andres Contreras
Summary: Lipid mobilization in adipose tissues, involving lipogenesis and lipolysis, plays a crucial role in regulating systemic energy metabolism. Reactive oxygen and nitrogen species (ROS and RNS) produced during lipolysis require a robust antioxidant response to maintain redox signaling. This review explores the production of ROS and RNS in adipose tissue, their regulation of lipid mobilization, and the impact of antioxidants.
Article
Plant Sciences
Amit Kumar, Mohammad Israil Ansari, Pradyumna Kumar Singh, Abu Baker, Kiran Gupta, Sudhakar Srivastava
Summary: Arsenic is a toxic element, but its stress can be mitigated by selenium and silica supplementation. This study found that the combined application of arsenic, selenium, and silica can reduce arsenic accumulation in rice plants and enhance their tolerance to arsenic stress.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Article
Agriculture, Dairy & Animal Science
Fawzia Hassan, Samia Mobarez, Manal Mohamed, Youssef Attia, Aml Mekawy, Khalid Mahrose
Summary: The study showed that heat stress in summer season affects the growth of rabbits, while dietary supplementation of zinc and/or selenium enriched spirulina as antioxidants can improve the growth performance of rabbits and enhance their antioxidant status.
Article
Biochemistry & Molecular Biology
Belinda J. Dunning, Arno R. Bourgonje, Marian L. C. Bulthuis, Jan Alexander, Jan O. Aaseth, Anders Larsson, Harry van Goor, Urban Alehagen
Summary: This study aimed to evaluate the effect of supplementation with selenium and coenzyme Q10 on serum free thiols and to study associations with the risk of cardiovascular mortality in elderly community-dwelling individuals. The results showed that supplementation with selenium and coenzyme Q10 significantly improved serum free thiol levels and reduced the risk of cardiovascular mortality in elderly individuals.
FREE RADICAL BIOLOGY AND MEDICINE
(2023)
Article
Environmental Sciences
Lina Chouchene, Kaouthar Kessabi, Marie-Madeleine Gueguen, Olivier Kah, Farzad Pakdel, Imed Messaoudi
Summary: This study provides new insights into the mechanisms of cadmium-induced toxicity in zebrafish larvae and the potential role of zinc in reversing these harmful effects. The results suggest that cadmium interferes with zinc metabolism, leading to its depletion and oxidative stress. However, supplementation of zinc can partially reverse the toxic effects of cadmium, possibly through its interaction with the toxic metal and improvement of oxidative status.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Maria Jose Lopez-Martinez, Damian Escribano, Alba Ortin-Bustillo, Lorena Franco-Martinez, Luis Guillermo Gonzalez-Arostegui, Jose Joaquin Ceron, Camila Peres Rubio
Summary: This study aimed to evaluate the changes in salivary biomarkers of redox status in pigs with experimentally induced sepsis. The results showed that sepsis caused significant changes in various antioxidant capacity markers in pig saliva, suggesting the potential use of these biomarkers for monitoring pig health.
Review
Biochemistry & Molecular Biology
Olga Vasileiadou, George G. Nastos, Panagiotis N. Chatzinikolaou, Dimitrios Papoutsis, Dimitra I. Vrampa, Spyridon Methenitis, Nikos V. Margaritelis
Summary: Mammalian skeletal muscles exhibit different redox properties and antioxidant enzyme activities between slow-twitch and fast-twitch muscles. Slow-twitch muscles have higher antioxidant enzyme activity, while fast-twitch muscles have higher oxidative production. This redox heterogeneity may have implications for muscle function and health research and provide an explanation for conflicting results about antioxidant supplement efficacy.
Article
Biochemistry & Molecular Biology
Quinlan R. McLaughlin, Mark P. Gunderson
Summary: This study examined the effects of sodium selenite on endogenous antioxidants and the impact of dimethoate on GST activity in signal crayfish. The results showed that neither sodium selenite nor dimethoate influenced GSH or MT concentrations, and both treatments did not affect GST activity.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Luiz Eduardo Baggio Savio, Raissa Leite-Aguiar, Vinicius Santos Alves, Robson Coutinho-Silva, Angela T. S. Wyse
Summary: Purinergic signaling is a crucial cell communication pathway mediated by extracellular nucleotides and nucleosides. Activation of P2 receptors influences the redox balance of cells, while enzymes like E-NTPDase1/CD39 and ecto-5'-nucleotidase/CD73 play key roles in regulating this process.
Review
Food Science & Technology
Guille Martinez-Negrin, Jarred P. Acton, Stuart P. Cocksedge, Stephen J. Bailey, Tom Clifford
Summary: The study found that (poly)phenols had no significant effect on muscle strength, peak power output, and fat loss, but enhanced exercise capacity. Isoflavones may contribute to enhancing exercise training adaptations, while resveratrol may compromise them. Additional high-quality research is needed to further investigate the effects of (poly)phenols on exercise training adaptations.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
