IL-33 is secreted by psoriatic keratinocytes and induces pro-inflammatory cytokines via keratinocyte and mast cell activation

Interleukin 33 as a Mechanically Responsive Cytokine Secreted by Living Cells

(2012) Rahul Kakkar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-33 induces skin inflammation with mast cell and neutrophil activation

(2011) Axel J. Hueber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Up-regulation of TNF-alpha secretion by cigarette smoke is mediated by Egr-1 in HaCaT human keratinocytes

(2010) Sang Hoon Jeong et al.   EXPERIMENTAL DERMATOLOGY

IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin

(2010) T. C. Theoharides et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis

(2009) Gaby Palmer et al.   ARTHRITIS AND RHEUMATISM

Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation

(2009) Shafaqat Ali et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interleukin-20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model

(2009) K. Stenderup et al.   BRITISH JOURNAL OF DERMATOLOGY

Intracellular signaling mechanisms regulating the activation of human eosinophils by the novel Th2 cytokine IL-33: implications for allergic inflammation

(2009) Joyce YS Chow et al.   Cellular & Molecular Immunology

The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: A novel immunological cascade with potential relevance in psoriasis

(2009) Kerstin Wolk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Increased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation

(2009) Ricardo Filipe da Silva Carvalho et al.   EXPERIMENTAL DERMATOLOGY

Recent developments in CCR2 antagonists

(2009) Mingde Xia et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Interleukin-33 Is Biologically Active Independently of Caspase-1 Cleavage

(2009) Dominique Talabot-Ayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Leukocytes, Keratinocytes, and Allergen-Specific IgE in the Development of Atopic Dermatitis

(2009) Thomas Werfel   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The cytokine interleukin-33 mediates anaphylactic shock

(2009) P. N. Pushparaj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-33 – cytokine of dual function or novel alarmin?

(2009) Guttorm Haraldsen et al.   TRENDS IN IMMUNOLOGY

Is there a role for mast cells in psoriasis?

(2008) Ilkka T. Harvima et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A–H2B acidic pocket

(2008) Lucie Roussel et al.   EMBO REPORTS

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One

IL-33 exacerbates antigen-induced arthritis by activating mast cells

(2008) D. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA