Mouse models of acute, chemical itch and pain in humans

BAM8-22 Peptide Produces Itch and Nociceptive Sensations in Humans Independent of Histamine Release

(2011) P. Sikand et al.   JOURNAL OF NEUROSCIENCE

TRPA1 is required for histamine-independent, Mas-related G protein–coupled receptor–mediated itch

(2011) Sarah R Wilson et al.   NATURE NEUROSCIENCE

Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons

(2011) S.-J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Itch- and Pain-related Behavioral Responses and µ-opoid Modulation in Mice

(2010) E Carstens et al.   ACTA DERMATO-VENEREOLOGICA

Cathepsin S Elicits Itch and Signals via Protease-Activated Receptors

(2010) Vemuri B. Reddy et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Facial Injections of Pruritogens and Algogens Excite Partly Overlapping Populations of Primary and Second-Order Trigeminal Neurons in Mice

(2010) T. Akiyama et al.   JOURNAL OF NEUROPHYSIOLOGY

Toll-like receptor 7 mediates pruritus

(2010) Tong Liu et al.   NATURE NEUROSCIENCE

VGLUT2-Dependent Glutamate Release from Nociceptors Is Required to Sense Pain and Suppress Itch

(2010) Yang Liu et al.   NEURON

Loss of Inhibitory Interneurons in the Dorsal Spinal Cord and Elevated Itch in Bhlhb5 Mutant Mice

(2010) Sarah E. Ross et al.   NEURON

Spontaneous itch in the absence of hyperalgesia in a mouse hindpaw dry skin model

(2010) Tasuku Akiyama et al.   NEUROSCIENCE LETTERS

Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch

(2010) T. Akiyama et al.   PAIN

Intraplantar injection of bergamot essential oil induces peripheral antinociception mediated by opioid mechanism

(2010) Tsukasa Sakurada et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

(2009) Qin Liu et al.   CELL

Pruritic and Nociceptive Sensations and Dysesthesias From a Spicule of Cowhage

(2009) R. H. LaMotte et al.   JOURNAL OF NEUROPHYSIOLOGY

Scratching Behavior and Fos Expression in Superficial Dorsal Horn Elicited by Protease-Activated Receptor Agonists and Other Itch Mediators in Mice

(2009) T. Akiyama et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice

(2009) L.S. Sorkin et al.   NEUROSCIENCE

Nalfurafine prevents 5′-guanidinonaltrindole- and compound 48/80-induced spinal c-fos expression and attenuates 5′-guanidinonaltrindole-elicited scratching behavior in mice

(2009) S. Inan et al.   NEUROSCIENCE

Similar itch and nociceptive sensations evoked by punctate cutaneous application of capsaicin, histamine and cowhage

(2009) Parul Sikand et al.   PAIN

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms

(2009) N. Imamachi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracisternal, But Not Intrathecal, Injection of Naloxone Inhibits Cutaneous Itch-Related Response in Mice

(2008) Yasushi Kuraishi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Histamine H4receptor antagonism reduces hapten-induced scratching behaviour but not inflammation

(2008) Kristine Roßbach et al.   EXPERIMENTAL DERMATOLOGY

Constitutive Activity at the Cannabinoid CB1 Receptor Is Required for Behavioral Response to Noxious Chemical Stimulation of TRPV1: Antinociceptive Actions of CB1 Inverse Agonists

(2008) B. Fioravanti et al.   JOURNAL OF NEUROSCIENCE

Cowhage-Evoked Itch Is Mediated by a Novel Cysteine Protease: A Ligand of Protease-Activated Receptors

(2008) V. B. Reddy et al.   JOURNAL OF NEUROSCIENCE

Behavioral differentiation between itch and pain in mouse

(2008) Steven G. Shimada et al.   PAIN