期刊
EXPERIMENTAL CELL RESEARCH
卷 317, 期 5, 页码 685-690出版社
ELSEVIER INC
DOI: 10.1016/j.yexcr.2010.10.020
关键词
Chemokines; Angiogenesis; Cancer
资金
- National Institutes of Health [HL97074, HL73848, CA87879, HL66027, HL98526]
Chemokines are a superfamily of structurally homologous heparin-binding proteins that influence tumor growth and metastasis. Several members of the CXC and CC chemokine families are potent inducers of neovascularization, whereas a subset of the CXC chemokines are potent inhibitors. In this paper, we review the current literature regarding the role of chemokines as mediators of tumor angiogenesis and neovascularization. (C) 2010 Elsevier Inc. All rights reserved.
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