Featured Article: Interactions of surface-expressed TLR-4 and endosomal TLR-9 accelerate lupus progression in anti-dsDNA antibody transgenic mice

Roles of Pro- and Anti-Inflammatory Cytokines in the Pathogenesis of SLE

(2012) Ding-Lei Su et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

B Cell and BAFF Dependence of IFN- -Exaggerated Disease in Systemic Lupus Erythematosus-Prone NZM 2328 Mice

(2011) N. Jacob et al.   JOURNAL OF IMMUNOLOGY

Blockade of TLR9 signaling in B cells impaired anti-dsDNA antibody production in mice induced by activated syngenic lymphocyte-derived DNA immunization

(2011) Min Chen et al.   MOLECULAR IMMUNOLOGY

Reversing interleukin-2 inhibition mediated by anti-double-stranded DNA autoantibody ameliorates glomerulonephritis in MRL-lpr/lpr mice

(2010) Ying-Chyi Song et al.   ARTHRITIS AND RHEUMATISM

TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy

(2010) S.A. Summers et al.   JOURNAL OF AUTOIMMUNITY

Transgenic overexpression of anti-double-stranded DNA autoantibody and activation of Toll-like receptor 4 in mice induce severe systemic lupus erythematosus syndromes

(2010) Tai-Ping Lee et al.   JOURNAL OF AUTOIMMUNITY

Emerging roles of TLR7 and TLR9 in murine SLE

(2009) Marie-Laure Santiago-Raber et al.   JOURNAL OF AUTOIMMUNITY

Signaling Crosstalk during Sequential TLR4 and TLR9 Activation Amplifies the Inflammatory Response of Mouse Macrophages

(2009) D. De Nardo et al.   JOURNAL OF IMMUNOLOGY

Glomerular expression of toll-like receptor-9 in lupus nephritis but not in normal kidneys: implications for the amplification of the inflammatory response

(2009) ED Papadimitraki et al.   LUPUS

Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus

(2009) Donna L Thibault et al.   ARTHRITIS RESEARCH & THERAPY

Glomerular targets of nephritogenic autoantibodies in systemic lupus erythematosus

(2008) Casandra C. van Bavel et al.   ARTHRITIS AND RHEUMATISM

Anti-DNA antibodies in the pathogenesis of lupus nephritis — The emerging mechanisms

(2008) Susan Yung et al.   AUTOIMMUNITY REVIEWS

Arginines in the CDR of anti-dsDNA autoantibodies facilitate cell internalizationviaelectrostatic interactions

(2008) Ying-Chyi Song et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Toll-like receptors and autoimmunity

(2007) Julia Hurst et al.   AUTOIMMUNITY REVIEWS