Stearoyl-CoA desaturase activity modulates the activation of epidermal growth factor receptor in human lung cancer cells

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health

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Hallmarks of Cancer: The Next Generation

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Cancer Cell Dependence on Unsaturated Fatty Acids Implicates Stearoyl-CoA Desaturase as a Target for Cancer Therapy

(2011) U. V. Roongta et al.   MOLECULAR CANCER RESEARCH

Roles of StearoylCoA Desaturase-1 in the Regulation of Cancer Cell Growth, Survival and Tumorigenesis

(2011) R. Ariel Igal   Cancers

Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association

(2010) Kristina R. Rogers et al.   CARCINOGENESIS

Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer

(2010) R. A. Igal   CARCINOGENESIS

Abrogation of De novo Lipogenesis by Stearoyl-CoA Desaturase 1 Inhibition Interferes with Oncogenic Signaling and Blocks Prostate Cancer Progression in Mice

(2010) V. Fritz et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of StearoylCoA Desaturase Activity Blocks Cell Cycle Progression and Induces Programmed Cell Death in Lung Cancer Cells

(2010) Daniel Hess et al.   PLoS One

Inhibition of Stearoyl-CoA Desaturase 1 Expression Induces CHOP-Dependent Cell Death in Human Cancer Cells

(2010) Mélaine Minville-Walz et al.   PLoS One

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells

(2009) Thomas W. Grunt et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors

(2009) Dmitry O. Koltun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel, potent, selective, and metabolically stable stearoyl-CoA desaturase (SCD) inhibitors

(2009) Dmitry O. Koltun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

(2009) P. S. Hammerman et al.   CLINICAL CANCER RESEARCH

ErbB receptors and signaling pathways in cancer

(2009) Nancy E Hynes et al.   CURRENT OPINION IN CELL BIOLOGY

Inhibition of StearoylCoA Desaturase-1 Inactivates Acetyl-CoA Carboxylase and Impairs Proliferation in Cancer Cells: Role of AMPK

(2009) Natalia Scaglia et al.   PLoS One

Brick by brick: metabolism and tumor cell growth

(2008) Ralph J DeBerardinis et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Endocytosis and intracellular trafficking of ErbBs

(2008) Alexander Sorkin et al.   EXPERIMENTAL CELL RESEARCH

Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation

(2008) Sylviane Lambert et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The challenge of lipid rafts

(2008) Linda J. Pike   JOURNAL OF LIPID RESEARCH

Spatiotemporal Analysis of Differential Akt Regulation in Plasma Membrane Microdomains

(2008) Xinxin Gao et al.   MOLECULAR BIOLOGY OF THE CELL

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE