The mouse is out of the bag: insights and perspectives on HIV-1-infected humanized mouse models

Remarkable Lethal G-to-A Mutations in vif-Proficient HIV-1 Provirus by Individual APOBEC3 Proteins in Humanized Mice

(2010) K. Sato et al.   JOURNAL OF VIROLOGY

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

(2010) Nathalia Holt et al.   NATURE BIOTECHNOLOGY

Systemic Administration of Antiretrovirals Prior to Exposure Prevents Rectal and Intravenous HIV-1 Transmission in Humanized BLT Mice

(2010) Paul W. Denton et al.   PLoS One

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r null humanized mice

(2010) L. D. Shultz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of memory and naïve CD8+ T lymphocytes in humanized NOD/SCID/IL-2Rγnull mice infected with CCR5-tropic HIV-1

(2010) Kei Sato et al.   VACCINE

A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model

(2009) S. Shimizu et al.   BLOOD

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

(2009) Till Strowig et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice

(2009) D. M. Brainard et al.   JOURNAL OF VIROLOGY

Evolution of the HIV-1 env Gene in the Rag2-/-  C-/- Humanized Mouse Model

(2009) W. L. Ince et al.   JOURNAL OF VIROLOGY

Suppression of Human Immunodeficiency Virus Type 1 (HIV-1) Viremia with Reverse Transcriptase and Integrase Inhibitors, CD4+ T-Cell Recovery, and Viral Rebound upon Interruption of Therapy in a New Model for HIV Treatment in the Humanized Rag2-/- c-/- Mouse

(2009) S. K. Choudhary et al.   JOURNAL OF VIROLOGY

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selective infection of CD4+ effector memory T lymphocytes leads to preferential depletion of memory T lymphocytes in R5 HIV-1-infected humanized NOD/SCID/IL-2Rγnull mice

(2009) Chuanyi Nie et al.   VIROLOGY

The APOBEC3 Cytidine Deaminases: An Innate Defensive Network Opposing Exogenous Retroviruses and Endogenous Retroelements

(2008) Ya-Lin Chiu et al.   Annual Review of Immunology

FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/- C-/- mice in vivo

(2008) Q. Jiang et al.   BLOOD

T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

(2008) Priti Kumar et al.   CELL

Two Distinct Modes of ESCRT-III Recognition Are Required for VPS4 Functions in Lysosomal Protein Targeting and HIV-1 Budding

(2008) Collin Kieffer et al.   DEVELOPMENTAL CELL

Cytidine Deaminases as a Weapon Against Retroviruses and a New Target for Antiviral Therapy

(2008) Akifumi Takaori-Kondo et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans

(2008) David I Watkins et al.   NATURE MEDICINE

Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice

(2008) Paul W Denton et al.   PLOS MEDICINE