Article
Virology
Milene S. Ferreira, Livia C. Martins, Karla F. L. de Melo, Wellington B. da Silva, Aline A. Imbeloni, Jose Augusto P. C. Muniz, Camille F. de Oliveira, Maria Nazare O. Freitas, Eder B. dos Santos, Liliane L. Chagas, Marcia B. M. Luz, Luiz A. D. de Queiroz, Robert B. Tesh, Pedro F. C. Vasconcelos
Summary: Between 2016 and 2018, Brazil experienced a major epidemic of yellow fever virus (YFV). This study investigated whether squirrel monkeys are a suitable model for studying yellow fever (YF).
Article
Multidisciplinary Sciences
Amber M. Paul, Eliah G. Overbey, Willian A. da Silveira, Nathaniel Szewczyk, Nina C. Nishiyama, Michael J. Pecaut, Sulekha Anand, Jonathan M. Galazka, Xiao Wen Mao
Summary: The study used a ground-based model to simulate spaceflight conditions and found negligible differences in immune differentials but large disparities in red blood cell differentials post-exposure. Analysis of spleen cells revealed expression profiles associated with inflammation and dysregulated immune function persisting to 1-week post-simulated spaceflight. Additionally, specific regulation pathways associated with human blood disease gene orthologs were noted.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Rafael Suarez-Del-Villar-Carrero, Diego Martinez-Urbistondo, Amanda Cuevas-Sierra, Iciar Ibanez-Sustacha, Alberto Candela-Fernandez, Andrea Dominguez-Calvo, Omar Ramos-Lopez, Juan Antonio Vargas, Guillermo Reglero, Paula Villares-Fernandez, Jose Alfredo Martinez
Summary: This study aimed to develop a model based on commonly requested hematological variables for early discrimination of patients with COVID-19 from those with other viral pneumonia. It identified 10 variables for the characterization of COVID-19 and found that low levels of leukocytes could serve as a primary marker for COVID-19 detection. The results suggest that commonly requested laboratory variables can help distinguish COVID-19 and stratify patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Ancuta Mihai, Diana Maria Chitimus, Ciprian Jurcut, Florin Cristian Blajut, Daniela Opris-Belinski, Constantin Caruntu, Ruxandra Ionescu, Ana Caruntu
Summary: This study aimed to evaluate the predictive potential of hematological and immunological parameters associated with peripheral neuropathy (PN) development in patients with Primary Sjogren syndrome (pSS). The results showed that neutrophils and neutrophil-to-lymphocyte ratio (NLR) were significantly higher in PN+ patients, while lymphocytes, monocytes, and monocyte-to-lymphocyte ratio (MLR) were significantly lower. Furthermore, immuno-inflammatory parameters such as gammaglobulins, complement fractions C3, C4, total proteins, and vitamin D were significantly lower in the PN+ group. Therefore, these biological parameters can be useful in predicting neurological involvement and monitoring disease progression in pSS patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Irina Gilyazova, Kadriia Enikeeva, Guzel Rafikova, Evelina Kagirova, Yuliya Sharifyanova, Dilara Asadullina, Valentin Pavlov
Summary: Bladder cancer is a common malignant tumor of the urogenital system, with over 500,000 new cases worldwide annually. Current diagnosis methods include cystoscopy and urine cytology, but they have limitations in sensitivity and invasiveness. There is a need to develop more reliable markers and tests for early detection of the disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Mo Li, Ghulam Nabi, Yanfeng Sun, Yang Wang, Limin Wang, Chuan Jiang, Pengxiu Cao, Yuefeng Wu, Dongming Li
Summary: The study found that birds in Shijiazhuang had more particles and toxic metals in their lungs and feathers compared to birds in Chengde. Additionally, Shijiazhuang birds had lower antioxidant capacity and immunological parameters. Despite showing signs of anemia, both populations had similar body conditions and blood parameters. These results suggest that urban birds can be used as bioindicators for assessing the effects of environmental pollution.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Biochemistry & Molecular Biology
Fakhir Najim K. Sabir, Edrees Mohammad Ameen
Summary: This study evaluated hematological, immunological, and inflammation markers in male and female patients infected with COVID-19 in Erbil city, Iraq. Significant differences were found in various markers between the patient group and control group. The results showed higher levels of WBC, IgG, IgM, CRP, Ferritin, and ESR in the patient group, while lymphocyte percentage was lower. No significant differences were observed in RBC, Hb, HCT, and thrombocytes between the two groups.
CELLULAR AND MOLECULAR BIOLOGY
(2023)
Article
Fisheries
Mohammad Hossein Khanjani, Moslem Sharifinia, Mauricio Gustavo Coelho Emerenciano
Summary: The innate immunity of invertebrates is a valuable foundation for studying the common biological responses to environmental changes. The intensification of aquaculture has led to the overuse of antibiotics and chemotherapeutics, resulting in the emergence of resistant microbes. Biofloc technology (BFT) offers a sustainable and eco-friendly approach to disease management in aquaculture by harnessing the power of antibiotics, probiotics, and prebiotics.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Hamed Abdollahpour, Bahram Falahatkar, Glen Van der Kraak
Summary: High concentration of T-4 treatment in sterlet sturgeon resulted in increased weight gain, red blood cell count, hemoglobin content, and hematocrit. The T-10 group showed the lowest levels of biochemical markers and the highest levels of immune-related substances.
Article
Immunology
Mehmet Tahir Huyut, Zubeyir Huyut, Fatih Ilkbahar, Cuma Mertoglu
Summary: This study investigated the relationship between routine blood values and mortality in COVID-19 patients and identified several biomarkers that can predict the risk of death, such as CRP, D-dimer, procalcitonin, ESR, etc.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2022)
Review
Oncology
Alissa Hendricks-Wenger, Ruby Hutchison, Eli Vlaisavljevich, Irving Coy Allen
Summary: Immunomodulating therapies have become a key approach in the treatment of cancer, addressing not only primary tumors but also circulating tumor cells and distant metastases. Focal ablation therapies, such as histotripsy, have shown promise in debulking tumors and stimulating an immune response. Studies also suggest that histotripsy may have reproducible immune effects across different tumor types.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Samantha J. Mayo, Sarah Brennenstuhl, Prabdeep Panesar, Ashley Leak Bryant
Summary: This study identified three distinct patterns of concerns among hematological cancer survivors and found that these patterns could be differentiated based on survivor characteristics.
Article
Multidisciplinary Sciences
Bruno Gustavo Muzzi Carvalho Carneiro, Andy Petroianu, Jose Augusto Nogueira Machado, Paula Martins Ferreira dos Anjos, Fabiana Rocha da Silva, Luiz Ronaldo Alberti, Vivian Resende, Sofia Candia Barrientos
Summary: The study found a lower occurrence of allergies in cancer patients, which was associated with higher levels of IL-2 cytokine and TGF-beta, and lower levels of IL-4, IL-17, and IL-1 beta. In head and neck, stomach, and prostate cancers, an immunosuppressive serum tumor environment was predominant.
SCIENTIFIC REPORTS
(2021)
Article
Parasitology
Safieh Shahvazi, Saleh Esmaeilzadeh, Somayeh Bahrami, Hossein Najafzadeh
Summary: This study investigated the relationship between liver fascioliasis and leiomyoma, as well as the alterations in polyamines in ruminants infected with F. gigantica. The infected animals showed significant changes in hematological parameters, including decreased RBC and PLT counts, and elevation in MCV, as well as higher levels of putrescine and spermine in liver tissues. IL-4 and TNF-alpha levels were not significantly changed in infected animals. The concurrent occurrence of leiomyoma and fascioliasis with polyamines elevation is reported for the first time, suggesting a need for further research into the role of polyamines in this interaction.
VETERINARY PARASITOLOGY
(2021)
Article
Genetics & Heredity
Kejun Liu, Lei Cui, Cunquan Li, Chaofeng Tang, Yiming Niu, Ji Hao, Yang Bu, Bendong Chen
Summary: Anillin actin-binding protein (ANLN) plays a crucial role in cell proliferation and migration. It is involved in tumor progression and immune evasion in various types of malignant tumors. ANLN expression is associated with prognosis, immune infiltration, and response to immune checkpoint inhibitors in cancer patients.
FRONTIERS IN GENETICS
(2022)
Article
Public, Environmental & Occupational Health
Samira Monteiro Silva, Alfredo Nicodemos Cruz Santana, Nayhane Nayara Barbosa da Silva, Maria Rita Carvalho Garbi Novaes
REVISTA DE SAUDE PUBLICA
(2019)
Article
Public, Environmental & Occupational Health
Vanessa Resende Nogueira Cruvinel, Carla Pintas Marques, Vanessa Cardoso, Maria Rita Carvalho Garbi Novaes, Wildo Navegantes Araujo, Antonia Angulo-Tuesta, Patricia Maria Fonseca Escalda, Dayani Galato, Petruza Brito, Everton Nunes da Silva
Review
Multidisciplinary Sciences
Rafaelly Stavale, Graziani Izidoro Ferreira, Joao Antonio Martins Galvao, Fabio Zicker, Maria Rita Carvalho Garbi Novaes, Cesar Messias de Oliveira, Dirce Guilhem
Article
Endocrinology & Metabolism
Luz Marina Alfonso Dutra, Mirian Conceicao Moura, Flaviene Alves Prado, Giselle De Oliveira Lima, Manuela Costa Melo, Rubens Nelson Morato Fernandez, Maria Rita Carvalho Garbi Novaes
DIABETOLOGY & METABOLIC SYNDROME
(2020)
Article
Pharmacology & Pharmacy
Ricardo Eccard da Silva, Elisangela da Costa Lima, Maria Rita C. G. Novaes, Claudia G. S. Osorio-de-Castro
FRONTIERS IN PHARMACOLOGY
(2020)
Article
Orthopedics
Viviane Cristina Uliana Peterle, Joao Carlos Geber Junior, Willian Darwin Junior, Alexandre Vasconcelos Lima, Paulo Emiliano Bezerra Junior, Maria Rita Carvalho Garbi Novaes
ACTA ORTOPEDICA BRASILEIRA
(2020)
Article
Psychiatry
Larissa de Freitas Oliveira, Einstein Francisco Camargos, Luciana Lilian Louzada Martini, Flavio Vieira Machado, Maria Rita Carvalho Garbi Novaes
Summary: This study examined psychotropic prescribing patterns for patients with Alzheimer's disease who exhibited aggression and agitation at specialist outpatient clinics in the Federal District of Brazil. The most common medications used were antidepressants, antipsychotics, benzodiazepines, and mood stabilizers, with Quetiapine and Citalopram being the most frequently prescribed. Multiple pharmacologic agents were often used together in this sample, with benzodiazepines being less frequently used.
PSYCHIATRY RESEARCH
(2021)
Article
Education & Educational Research
Ubirajara Jose Picanco de Miranda Junior, Maria Rita Carvalho Garbi Novaes, Henrique Batista Araujo Santos, Joao Fellipe Santos Tatsch, Rafael Sanches Ferreira, Wilton Paulo de Freitas Martins Vieira, Luis Velez Lapao
Summary: This study examined the organizational identity and success factors of a public higher education institution, identifying six central elements: political/ideological conflict, active teaching and learning methods, campus locations/separation, time of existence, teaching careers, and political-administrative transformations. The results showed that despite weaknesses, the employees still identified strongly with the institution.
BMC MEDICAL EDUCATION
(2021)
Article
Multidisciplinary Sciences
Marta David Rocha de Moura, Paulo Roberto Margotto, Karina Nascimento Costa, Maria Rita Carvalho Garbi Novaes
Summary: This study found that gestational hypertension may have a negative impact on premature newborns, leading to lower birth weights, increased risk of SGA, higher mortality and enterocolitis rates in the neonatal period. However, there were no significant differences in weight and survival at 18 months of age.
Article
Nutrition & Dietetics
Renata Ferreira Silva, Maria Rita Carvalho Garbi Novaes, Dirce Bellezi Guilhem
NUTRICION HOSPITALARIA
(2020)
Article
Nutrition & Dietetics
Deyse Anne Lima Costa, Ana Lucia Ribeiro Salomon, Simone Gonzaga do Carmo, Renata Costa Fortes
RBONE-REVISTA BRASILEIRA DE OBESIDADE NUTRICAO E EMAGRECIMENTO
(2019)
Article
Public, Environmental & Occupational Health
Maria Rita Carvalho Garbi Novaes, Marcia Luz da Motta, Flavia Tavares Silva Elias, Ricardo Eccard da Silva, Claudia Cardoso Gomes da Silva, Vanessa de Amorim Teixeira Baliero, Marge Tenorio
CIENCIA & SAUDE COLETIVA
(2019)
Article
Nursing
Natallia Rodrigues Araujo da Silva, Gabriela Cristina Cantisani Padua, Maria Rita Carvalho Garbi Novaes, Dirce Bellezi Guilhem
REVISTA DA ESCOLA DE ENFERMAGEM DA USP
(2020)
Article
Nursing
Katia Rodrigues Menezes, Maria Rita Carvalho Garbi Novaes
REVISTA BRASILEIRA DE ENFERMAGEM
(2020)
Article
Nursing
Caroline Soares Menezes, Renata Costa Fortes
REVISTA LATINO-AMERICANA DE ENFERMAGEM
(2019)