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Mitochondrial Plasticity with Exercise Training and Extreme Environments

EXERCISE AND SPORT SCIENCES REVIEWS (2014)

期刊

EXERCISE AND SPORT SCIENCES REVIEWS

卷 42, 期 4, 页码 169-174

出版社

LIPPINCOTT WILLIAMS & WILKINS

DOI: 10.1249/JES.0000000000000025

关键词

exercise training; mitochondria; OXPHOS; substrates; coupling; environment

类别

Physiology Sport Sciences

资金

Swedish National Centre for Research in Sports

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Protocol

Reagent

摘要

Mitochondria form a reticulum in skeletal muscle. Exercise training stimulates mitochondrial biogenesis, yet an emerging hypothesis is that training also induces qualitative regulatory changes. Substrate oxidation, oxygen affinity, and biochemical coupling efficiency may be regulated differentially with training and exposure to extreme environments. Threshold training doses inducing mitochondrial upregulation remain to be elucidated considering fitness level.

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