Article
Multidisciplinary Sciences
Aidan M. C. Couzens, Karen E. Sears, Martin Rucklin
Summary: The study investigates how development influenced the early dental evolution in placental mammals, focusing on the transition from a triangular upper molar to a more complex upper molar with a rectangular cusp pattern. Through simulations, researchers found that increased self-regulation of molecular activator led to accelerated evolutionary increases in enamel knot number, creating a lateral knot arrangement. They also suggest that relatively small changes in activation superimposed on ancestral molar growth pattern could recreate key changes in cusps, influencing the divergence of placental molar dentition.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Edoardo Filippi-Mazzola, Federica Bianchi, Ernst C. C. Wit
Summary: The citation network of patents citing prior art arises from the legal obligation of patent applicants to properly disclose their invention. One way to study the relationship between current patents and their antecedents is by analyzing the similarity between the textual elements of patents. This paper investigates the drivers of the apparent decrease in patent similarity scores using a computationally efficient measure of patent similarity and advanced NLP tools.
Article
Business
Johannes Wachs, Balazs Vedres
Summary: Crowdfunding provides inventors and entrepreneurs with alternative access to resources and fosters innovation, making crowdfunded products more distinctive and innovative. Analysis of board games data shows that crowdfunded games are more likely to have novel combinations of mechanisms, with lasting impact on traditionally funded products.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2021)
Article
Biotechnology & Applied Microbiology
Ken Taylor, Simon Woods, Alex Johns, Heath Murray
Summary: This paper presents a case study of the implementation of Responsible Innovation (RI) in a UK-based synthetic biology project, examining its impact and benefits. It highlights the importance of interdisciplinary collaboration and shared reflection on research. The study resulted in modifications to a key project product, going beyond institutional requirements, and emphasizes the continued need for interdisciplinary collaboration and the utility of the Responsible Innovation framework. It concludes with observations on the challenges of sustaining such collaborations.
NEW GENETICS AND SOCIETY
(2023)
Article
Business
Seokbeom Kwon
Summary: This study examines the relationship between interdisciplinarity in knowledge integration for research and its unique knowledge input for technology development. The study finds that interdisciplinarity is positively associated with uniqueness in its contribution to technology development only when the research has funding support. It also finds that interdisciplinarity is positively associated with the non-unique impact of research on technology development regardless of funding support.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2022)
Review
Developmental Biology
Veronica Biga, Tom P. J. Wyatt, Diana Pinheiro
Summary: Across developmental systems, quantitative and imaging-based approaches have provided unprecedented resolution of dynamic changes in gene regulation and cell fate specification, enabling the construction of comprehensive theoretical models. However, gaining a cross-scale understanding of developmental systems requires further collaboration between disciplines. The Company of Biologists workshop 'Fostering quantitative modelling and experimentation in Developmental Biology' highlights exciting multi-disciplinary research in this field.
Article
Biochemistry & Molecular Biology
Zheng Li, Yiyuan Li, Allen Z. Xue, Vy Dang, V. Renee Holmes, J. Spencer Johnston, Jeffrey E. Barrick, Nancy A. Moran
Summary: In this study, researchers addressed the genomic basis of evolutionary novelties in the glassy-winged sharpshooter, an agricultural pest. They generated a chromosome-level genome assembly for the species and used additional data to identify genes involved in the production of proteinaceous structures and interactions with bacterial symbionts. The study also revealed ancient horizontal gene transfer events in leafhoppers and highlighted the combination of acquiring novel genes and symbiotic associations as important drivers of evolutionary novelties.
MOLECULAR BIOLOGY AND EVOLUTION
(2022)
Article
Engineering, Industrial
Mark B. van der Waal, Jelle J. Feddema, Linda H. M. van de Burgwal
Summary: The COVID-19 pandemic has sparked a debate on the costs and benefits of patents. To facilitate constructive debate, a comprehensive synthesis of contemporary reports on the effects of patents was performed. The synthesis revealed a complex interplay of effects and highlighted the context-dependency and relativity of these effects. Additional analysis identified common denominators for disparate effects, which can guide broad-based system improvements. Addressing issues of low patent quality and profiteering is crucial.
Article
Zoology
William C. Barley, Luisa Ruge-Jones, Aimy Wissa, Andrew Suarez, Marianne Alleyne
Summary: This paper discusses the interdisciplinary challenges in bioinspired design, specifically focusing on the complex motivations, misperceptions, and institutional barriers faced by collaborating researchers. Specific recommendations are proposed to address these challenges.
INTEGRATIVE AND COMPARATIVE BIOLOGY
(2022)
Article
Engineering, Multidisciplinary
Hartmut Witte
Summary: Biomechatronics combines biomimetics and biomedical engineering methods, which are mutually supportive rather than competing. Categorizing biomechatronics under biomimetics or biomedical engineering is not wise as it undermines the strength of combining both methods. Additionally, the training of specialists is crucial in this field.
Article
Ecology
Masato Yamamichi, Stephen P. Ellner, Nelson G. Hairston Jr
Summary: Studies on eco-evolutionary dynamics have integrated evolution with ecological processes and interspecific interactions, but often neglected various evolutionary processes. This paper argues for the consideration of drift, mutation, disruptive selection, and evolution driven by relative fitness differences to better understand nature's eco-evolutionary dynamics.
Article
Multidisciplinary Sciences
Naoki Hiratani, Peter E. Latham
Summary: This study investigates the relationship between neural circuit structure and learning efficiency by analyzing the olfactory system. The results suggest that optimal neural architecture is influenced by the species' longevity and the genetic specification of the olfactory circuit.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Business
Athanasia Lampraki (Nansy), Christos Kolympiris, Thorsten Grohsjean, Linus Dahlander
Summary: The paradox of rejecting novel ideas while being motivated to select them exists in many realms. This study investigates an external solution to this paradox by examining how seconded employees can increase the selection of novel ideas. Through both quantitative data and interviews, the study finds that seconded employees choose more novel ideas and influence permanent staff to do the same. These findings suggest a simple intervention can significantly boost the acceptance of innovative ideas, offering valuable insights for those in the science and innovation fields. Understanding this dynamic can empower managers to strategically leverage seconded employees, fostering a more innovative and adaptive organizational culture.
STRATEGIC MANAGEMENT JOURNAL
(2023)
Article
Evolutionary Biology
Charles Feigin, Sha Li, Jorge Moreno, Ricardo Mallarino
Summary: This article discusses the practical implications of the gene regulatory network (GRN) concept in evolutionary developmental biology research and how to design experiments and projects accordingly. By mapping familiar biological notions to more abstract components of GRN models, and by using various functional genomic approaches for experimental validation, the molecular basis of phenotypic diversity can be elucidated.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION
(2023)
Article
Computer Science, Artificial Intelligence
Nicolas Kamel, Nawwaf Kharma, Jonathan Perreault
Summary: A main goal of synthetic biology is to design logic gates using ribozymes to reprogram cells for user-defined tasks. However, existing ribogate design approaches face limitations in terms of complexity, diversity, ease of use, and reliability. To address these challenges, a multi-objective evolutionary algorithm called Truth-Seq-Er was introduced, which generates diverse and complex ribogate designs while improving user-friendliness and accessibility. The algorithm eliminates the need for domain knowledge and streamlines the design process by requiring only a target Boolean function as input. The results demonstrate the potential of Truth-Seq-Er in advancing ribogate design and contributing to the development of novel synthetic biology and unconventional computing applications.
GENETIC PROGRAMMING AND EVOLVABLE MACHINES
(2023)
Article
Evolutionary Biology
Ingo Brigandt
EVOLUTION & DEVELOPMENT
(2020)
Article
History & Philosophy Of Science
James DiFrisco, Alan C. Love, Gunter P. Wagner
BIOLOGY & PHILOSOPHY
(2020)
Article
History & Philosophy Of Science
Alan C. Love
PHILOSOPHY OF SCIENCE
(2020)
Article
History & Philosophy Of Science
Scott Lidgard, Alan C. Love
Summary: Researchers suggested rethinking the function of the living fossil concept, arguing that concepts in science have useful roles beyond just categorization. They discussed the diverse and sometimes conflicting criteria associated with categorizing items as living fossils and how these criteria are closely related to answering questions about prolonged evolutionary stasis.
BIOLOGY & PHILOSOPHY
(2021)
Editorial Material
Biology
Alan C. Love, Max Dresow
Article
Ecology
Alan Love, Gunter P. Wagner
Summary: It is widely accepted that stressful conditions can facilitate evolutionary change by increasing heritable variation and promoting rapid adaptive evolution. Stressors can be categorized into two types based on their effect on functional integrity: stress-responsive mechanisms that maintain adaptive fit with the environment, and stress-responsive mechanisms specific to stressors that lead to the emergence of novelties through compensation. Our model explains the evolutionary transformation of an immediate response to acute stress into routine protection from recurring stressors by considering cost-benefit trade-offs. Examples from different levels of organization support the general principle of evolutionary origination based on the ability to switch between regulatory states related to reproduction and survival.
Review
Biodiversity Conservation
Alan C. Love, Mark Grabowski, David Houle, Lee Hsiang Liow, Arthur Porto, Masahito Tsuboi, Kjetil L. Voje, Gene Hunt
Summary: This paper discusses the importance of evolvability in evolutionary biology and its application in paleontology. Despite challenges in applying tools from evolvability literature to the fossil record, the fossil record provides unique data sources that capture evolutionary patterns and assist evolutionary biologists in their research. Additionally, combining neontological and paleontological approaches is an important direction for future studies.
Article
Anatomy & Morphology
James DiFrisco, Alan C. Love, Gunter P. Wagner
Summary: This article discusses the pervasiveness of gene sharing in evolution and the issue of homology across different lineages. The authors propose a new theoretical classification to address the problem of determining homology. They argue that the concept of serial homology should primarily be applied to developmentally individualized body parts and suggest a hierarchical, phylogenetic interpretation.
JOURNAL OF MORPHOLOGY
(2023)
Book Review
History & Philosophy Of Science
Ingo Brigandt
JOURNAL FOR GENERAL PHILOSOPHY OF SCIENCE
(2023)
Article
Anatomy & Morphology
Devin Y. Gouvea, Ingo Brigandt
Summary: The term homology has different definitions in different fields, and there are two main approaches to unify these definitions: preserving the distinguishing features related to specific research goals or seeking conceptual unification by integrating various definitions. This paper proposes an alternative strategy based on scientific concepts as research tools and illustrates its effectiveness through two case studies.
JOURNAL OF MORPHOLOGY
(2023)
Letter
Ecology
Alan C. Love, Gunter P. Wagner
TRENDS IN ECOLOGY & EVOLUTION
(2023)
Article
Philosophy
Ingo Brigandt
Summary: Philosophical work on science and values has increasingly focused on the concerns of society and stakeholders affected by science and policy, leading to the development of socially relevant and socially engaged philosophy of science. This special issue showcases instances of socially relevant philosophy of science.
CANADIAN JOURNAL OF PHILOSOPHY
(2022)
Article
Philosophy
Ingo Brigandt
Summary: Recent attempts to develop a general theory of the properties that all natural kinds possess may have been futile, and instead, a general methodological framework for studying kinds from a philosophical perspective should be developed. This framework should consider human aims and non-epistemic goals. Furthermore, it is important to stop using the term "natural kinds" as it obscures the significance of human interests and the social processes that underlie many kinds.
CANADIAN JOURNAL OF PHILOSOPHY
(2022)
Article
Philosophy
Alan C. Love
Article
Behavioral Sciences
Emily A. Willoughby, Alan C. Love, Matt McGue, William G. Iacono, Jack Quigley, James J. Lee
