The impact of natural selection on health and disease: uses of the population genetics approach in humans

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Human skin pigmentation, migration and disease susceptibility

(2012) N. G. Jablonski et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Exploring the role of copy number variants in human adaptation

(2012) Rebecca C. Iskow et al.   TRENDS IN GENETICS

Human Copy Number Variation and Complex Genetic Disease

(2011) Santhosh Girirajan et al.   Annual Review of Genetics

A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk

(2011) Chang Sun et al.   HUMAN GENETICS

The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans

(2011) L. Abi-Rached et al.   SCIENCE

Peto's Paradox: evolution's prescription for cancer prevention

(2011) Aleah F. Caulin et al.   TRENDS IN ECOLOGY & EVOLUTION

A worldwide correlation of lactase persistence phenotype and genotypes

(2010) Yuval Itan et al.   BMC EVOLUTIONARY BIOLOGY

The hygiene hypothesis: an evolutionary perspective

(2010) Manuela Sironi et al.   MICROBES AND INFECTION

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Genetic history of an archaic hominin group from Denisova Cave in Siberia

(2010) David Reich et al.   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Formulating a Historical and Demographic Model of Recent Human Evolution Based on Resequencing Data from Noncoding Regions

(2010) Guillaume Laval et al.   PLoS One

Evolutionary perspectives on health and medicine

(2010) S. C. Stearns et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude

(2010) X. Yi et al.   SCIENCE

A Draft Sequence of the Neandertal Genome

(2010) R. E. Green et al.   SCIENCE

Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data

(2010) Abigail Bigham et al.   PLoS Genetics

Recent Natural Selection Identifies a Genetic Variant in a Regulatory Subunit of Protein Phosphatase 2A that Associates with Altered Cancer Risk and Survival

(2009) L. F. Grochola et al.   CLINICAL CANCER RESEARCH

Constructing genomic maps of positive selection in humans: Where do we go from here?

(2009) J. M. Akey   GENOME RESEARCH

Signals of recent positive selection in a worldwide sample of human populations

(2009) J. K. Pickrell et al.   GENOME RESEARCH

Acute Lymphoblastic Leukemia in Adolescents and Young Adults

(2009) Josep-Maria Ribera et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

From evolutionary genetics to human immunology: how selection shapes host defence genes

(2009) Luis B. Barreiro et al.   NATURE REVIEWS GENETICS

Spatial patterns of variation due to natural selection in humans

(2009) John Novembre et al.   NATURE REVIEWS GENETICS

Genetics and the understanding of selection

(2009) Laurence D. Hurst   NATURE REVIEWS GENETICS

Positively Selected G6PD-Mahidol Mutation Reduces Plasmodium vivax Density in Southeast Asians

(2009) C. Louicharoen et al.   SCIENCE

The Role of Geography in Human Adaptation

(2009) Graham Coop et al.   PLoS Genetics

Independent Introduction of Two Lactase-Persistence Alleles into Human Populations Reflects Different History of Adaptation to Milk Culture

(2008) Nabil Sabri Enattah et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Natural Selection on Genes that Underlie Human Disease Susceptibility

(2008) Ran Blekhman et al.   CURRENT BIOLOGY

Natural selection has driven population differentiation in modern humans

(2008) Luis B Barreiro et al.   NATURE GENETICS

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

(2008) Kelly A McGowan et al.   NATURE GENETICS

Demeter's legacy: rapid changes to our genome imposed by diet

(2008) E PATIN et al.   TRENDS IN ECOLOGY & EVOLUTION

A Genome-Wide Association Study Identifies Novel Alleles Associated with Hair Color and Skin Pigmentation

(2008) Jiali Han et al.   PLoS Genetics