Implications of sex-specific selection for the genetic basis of disease

THE EFFECTS OF SELECTION AND GENETIC DRIFT ON THE GENOMIC DISTRIBUTION OF SEXUALLY ANTAGONISTIC ALLELES

(2012) Charles Mullon et al.   EVOLUTION

ANTAGONISTIC VERSUS NONANTAGONISTIC MODELS OF BALANCING SELECTION: CHARACTERIZING THE RELATIVE TIMESCALES AND HITCHHIKING EFFECTS OF PARTIAL SELECTIVE SWEEPS

(2012) Tim Connallon et al.   EVOLUTION

MALE-BIASED FITNESS EFFECTS OF SPONTANEOUS MUTATIONS INDROSOPHILA MELANOGASTER

(2012) Nathaniel P. Sharp et al.   EVOLUTION

A General Population Genetic Framework for Antagonistic Selection That Accounts for Demography and Recurrent Mutation

(2012) T. Connallon et al.   GENETICS

Sex-specific differences in effect size estimates at established complex trait loci

(2012) Gisela Orozco et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Positive Selection on the Osteoarthritis-Risk and Decreased-Height Associated Variants at the GDF5 Gene in East Asians

(2012) Dong-Dong Wu et al.   PLoS One

Constraints on the coevolution of contemporary human males and females

(2012) S. C. Stearns et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Function, Developmental Genetics, and Fitness Consequences of a Sexually Antagonistic Trait

(2012) A. Khila et al.   SCIENCE

Experimental Evolution of a Novel Sexually Antagonistic Allele

(2012) Rebecca Dean et al.   PLoS Genetics

Evidence of Sex-Modulated Association of ZNF804A with Schizophrenia

(2011) Fengyu Zhang et al.   BIOLOGICAL PSYCHIATRY

Experimental mutation-accumulation on the X chromosome of Drosophila melanogaster reveals stronger selection on males than females

(2011) Martin A Mallet et al.   BMC EVOLUTIONARY BIOLOGY

THE POTENTIAL FOR SEXUALLY ANTAGONISTIC POLYMORPHISM IN DIFFERENT GENOME REGIONS

(2011) Crispin Y. Jordan et al.   EVOLUTION

To stratify or not to stratify: power considerations for population-based genome-wide association studies of quantitative traits

(2011) Gundula Behrens et al.   GENETIC EPIDEMIOLOGY

Sex differences in disease risk from reported genome-wide association study findings

(2011) Linda Y. Liu et al.   HUMAN GENETICS

DDT resistance, epistasis and male fitness in flies

(2011) D. T. SMITH et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Crohn's Disease and Genetic Hitchhiking at IBD5

(2011) C. D. Huff et al.   MOLECULAR BIOLOGY AND EVOLUTION

Pathology from evolutionary conflict, with a theory of X chromosome versus autosome conflict over sexually antagonistic traits

(2011) S. A. Frank et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental Evidence Supports a Sex-Specific Selective Sieve in Mitochondrial Genome Evolution

(2011) P. Innocenti et al.   SCIENCE

Gene–environment interactions in human disease: nuisance or opportunity?

(2011) Carole Ober et al.   TRENDS IN GENETICS

Genic Capture, Sex Linkage, and the Heritability of Fitness

(2010) Tim Connallon   AMERICAN NATURALIST

Maltreatment, MAOA, and Delinquency: Sex Differences in Gene–Environment Interaction in a Large Population-Based Cohort of Adolescents

(2010) C. Åslund et al.   BEHAVIOR GENETICS

FITNESS VARIATION DUE TO SEXUAL ANTAGONISM AND LINKAGE DISEQUILIBRIUM

(2010) Manus M. Patten et al.   EVOLUTION

Meta-analysis of sex-specific genome-wide association studies

(2010) Reedik Magi et al.   GENETIC EPIDEMIOLOGY

Allowing for sex differences increases power in a GWAS of multiplex Autism families

(2010) A T-H Lu et al.   MOLECULAR PSYCHIATRY

Extreme Evolutionary Disparities Seen in Positive Selection across Seven Complex Diseases

(2010) Erik Corona et al.   PLoS One

Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies

(2010) A. Eyre-Walker   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Sexually Antagonistic Genes of Drosophila melanogaster

(2010) Paolo Innocenti et al.   PLOS BIOLOGY

MAINTENANCE OR LOSS OF GENETIC VARIATION UNDER SEXUAL AND PARENTAL ANTAGONISM AT A SEX-LINKED LOCUS

(2009) Manus M. Patten et al.   EVOLUTION

SEX-SPECIFIC GENETIC VARIANCE AND THE EVOLUTION OF SEXUAL DIMORPHISM: A SYSTEMATIC REVIEW OF CROSS-SEX GENETIC CORRELATIONS

(2009) Jocelyn Poissant et al.   EVOLUTION

Genic variation at sex-linked loci: Quantification of regular selection models

(2009) PEKKA PAMILO   HEREDITAS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Intralocus sexual conflict

(2009) Russell Bonduriansky et al.   TRENDS IN ECOLOGY & EVOLUTION

PURGING THE GENOME WITH SEXUAL SELECTION: REDUCING MUTATION LOAD THROUGH SELECTION ON MALES

(2008) Michael C. Whitlock et al.   EVOLUTION

Assessing the extent of genome-wide intralocus sexual conflict via experimentally enforced gender-limited selection

(2008) E. H. MORROW et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Personal genomes: The case of the missing heritability

(2008) Brendan Maher   NATURE

Common and rare variants in multifactorial susceptibility to common diseases

(2008) Walter Bodmer et al.   NATURE GENETICS

Sex-specific genetic architecture of human disease

(2008) Carole Ober et al.   NATURE REVIEWS GENETICS

Genome-Wide Association Identifies a Common Variant in the Reelin Gene That Increases the Risk of Schizophrenia Only in Women

(2008) Sagiv Shifman et al.   PLoS Genetics

Assessing the Evolutionary Impact of Amino Acid Mutations in the Human Genome

(2008) Adam R. Boyko et al.   PLoS Genetics

Intersexual ontogenetic conflict

(2003) W. R. Rice et al.   JOURNAL OF EVOLUTIONARY BIOLOGY