Article
Psychology, Multidisciplinary
Rosa Silva, Elzbieta Bobrowicz-Campos, Paulo Santos-Costa, Ana Rita Cruz, Joao Apostolo
Summary: The study found that the individual cognitive stimulation program implemented by caregivers showed promising results in improving the cognition of persons with cognitive impairment, but had no significant impact on caregivers' physical and mental health.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Health Care Sciences & Services
Kayoko Taguchi, Noriko Numata, Rieko Takanashi, Ryo Takemura, Tokiko Yoshida, Kana Kutsuzawa, Kensuke Yoshimura, Natsuko Nozaki-Taguchi, Seiji Ohtori, Eiji Shimizu
Summary: This study aimed to examine the effectiveness of an integrated cognitive behavioral therapy program with new components delivered via videoconferencing. The results showed that while it did not reduce pain intensity, it did decrease pain interference and was cost-effective.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Geriatrics & Gerontology
Valeska Marinho, Elodie Bertrand, Renata Naylor, Iris Bomilcar, Jerson Laks, Aimee Spector, Daniel C. Mograbi
Summary: The study showed that Cognitive Stimulation Therapy (CST) is a feasible and effective intervention for improving mood and activities of daily living in people with mild to moderate dementia. It had good acceptance among participants and showed potential for broader application in the Brazilian context.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2021)
Article
Health Care Sciences & Services
Yiwen Wu, Xin Li, Yuxin Zhou, Rui Gao, Kaifeng Wang, Huiling Ye, Na Lyu, Chun Wang, Ning Zhang, Zhen Wang, Qing Fan
Summary: This study compares the efficacy and cost-effectiveness of internet-based cognitive behavioral therapy (ICBT) combined with medication, face-to-face cognitive behavioral group therapy (CBGT) combined with medication, and conventional medical treatment for adults with obsessive-compulsive disorder (OCD). The results show that ICBT combined with medication is as effective as CBGT combined with medication for treating OCD and is more cost-effective.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Psychology, Clinical
Catherine Henderson, Martin Knapp, Susan Stirling, Lee Shepstone, Juliet High, Clive Ballard, Peter Bentham, Alistair Burns, Nicolas Farina, Chris Fox, Julia Fountain, Paul Francis, Robert Howard, Iracema Leroi, Gill Livingston, Ramin Nilforooshan, Shirley Nurock, John T. O'Brien, Annabel Price, Ann Marie Swart, Naji Tabet, Tanya Telling, Alan J. Thomas, Sube Banerjee
Summary: This study compared the costs and cost-effectiveness of mirtazapine versus placebo in treating individuals with Alzheimer's disease and agitation. The results showed no significant differences in behavior and social care costs between the two groups over 12 weeks, and mirtazapine was not considered a cost-effective strategy.
INTERNATIONAL PSYCHOGERIATRICS
(2022)
Review
Psychology
Robin M. T. Cafferata, Ben Hicks, Claudia C. von Bastian
Summary: Cognitive stimulation shows medium-sized effect on global cognition, with most effects supported by substantial and strong Bayesian evidence, although methodological issues highlight the need for better controlled studies for more compelling evidence.
PSYCHOLOGICAL BULLETIN
(2021)
Article
Geriatrics & Gerontology
Isabel Gomez-Soria, Chelo Ferreira, Barbara Olivan-Blazquez, Alejandra Aguilar-Latorre, Estela Calatayud
Summary: The purpose of this research was to evaluate the effects of a personalized-adapted cognitive stimulation program in older adults on global cognition, neuropsychological constructs, activities of daily living, and mood. The results showed that the intervention had a tendency to improve global cognition and different cognitive functions for groups without deterioration or with a mild deterioration, and improved anxiety for the group with moderate deterioration.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Article
Geriatrics & Gerontology
Elodie Bertrand, Valeska Marinho, Renata Naylor, Iris Bomilcar, Jerson Laks, Aimee Spector, Daniel C. Mograbi
Summary: This study explores the impact of a Brazilian adapted version of Cognitive Stimulation Therapy (CST-Brasil) on self-awareness in people with dementia. The results suggest that CST may improve metacognitive abilities in patients.
CLINICAL GERONTOLOGIST
(2023)
Article
Nursing
Lily Dongxia Xiao, Jing Wang, Julie Ratcliffe, Shahid Ullah, Henry Brodaty, Bianca Brijnath, Hui-Chen (Rita) Chang, Huali Wang, Chia-Chi Chang, Timothy Kwok, Mingxia Zhu
Summary: This study aims to evaluate the effectiveness and cost-effectiveness of a Chinese iSupport for Dementia program through a nurse-led multicentre randomized controlled trial. The study will recruit participants from Australia and Greater China and assess various outcome measures, including the impact on caregivers' health and quality of life. The findings of this research will contribute to policy and practice development.
JOURNAL OF ADVANCED NURSING
(2022)
Article
Clinical Neurology
Myoung-Hwan Ko, Ju-Yul Yoon, Yun-Ju Jo, Mi-Nam Son, Da-Sol Kim, Gi-Wook Kim, Yu Hui Won, Sung-Hee Park, Jeong-Hwan Seo, Yun-Hee Kim
Summary: This study evaluated the cognitive improvement and feasibility of remotely supervised transcranial direct current stimulation (RS-tDCS) in patients with chronic stroke. The results showed significant improvement in cognitive function, particularly in patients with lower baseline cognitive scores and left hemispheric lesions.
Article
Nursing
Qiao-hong Yang, Xia Lyu, Qing-ran Lin, Zi-wen Wang, Li Tang, Yu Zhao, Qi-yuan Lyu
Summary: The study evaluated the effects of a multicomponent intervention on Chinese patients with mild cognitive impairment. The results showed that the intervention had beneficial effects on cognitive function, physical function, depression symptoms, and quality of life, slowing the progression of the disease.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Article
Geriatrics & Gerontology
Robert Howard, Rebecca Gathercole, Rosie Bradley, Emma Harper, Lucy Davis, Lynn Pank, Natalie Lam, Emma Talbot, Emma Hooper, Rachel Winson, Bethany Scutt, Victoria Ordonez Montano, Samantha Nunn, Grace Lavelle, Andrew Bateman, Peter Bentham, Alistair Burns, Barbara Dunk, Kirsty Forsyth, Chris Fox, Fiona Poland, Iracema Leroi, Stanton Newman, John O'Brien, Catherine Henderson, Martin Knapp, John Woolham, Richard Gray
Summary: The study found that the use of assistive technology and telecare (ATT) did not significantly prolong the time for people with dementia to live independently and was not cost-effective. Participants in the ATT group had fewer quality-adjusted life years (QALYs) based on participant-reported EQ-5D at 104 weeks.
Review
Cell Biology
Zihan Ding, Pui-Ying Leung, Tsz-lok Lee, Agnes S. Chan
Summary: This study examines the effectiveness of lifestyle medicine on cognitive functions among people with mild cognitive impairment (MCI) and dementia through a systematic review and meta-analysis of randomized controlled trials (RCTs). The results show that exercise is the most promising lifestyle intervention that improves cognitive functions in MCI and dementia patients, with better results observed in MCI. Interventions on stress management or emotional well-being did not have a significant effect on MCI patients, and there is insufficient evidence to conclude for dementia patients.
AGEING RESEARCH REVIEWS
(2023)
Article
Medicine, General & Internal
Juan Zhao, Wei Zhou, Yangfeng Wu, Xiaoyan Yan, Li Yang, Zhuoli Zhang
Summary: Compared to continuing TNFi and MTX therapy, csDMARDs triple therapy was found to be a more cost-effective option for reducing relapse in RA patients who have achieved low disease activity.
CHINESE MEDICAL JOURNAL
(2022)
Article
Clinical Neurology
Sara Bernini, Silvia Panzarasa, Elena Sinforiani, Silvana Quaglini, Stefano F. Cappa, Chiara Cerami, Cristina Tassorelli, Tomaso Vecchi, Sara Bottiroli
Summary: This study aims to compare the effects of computer-based interventions on participants with neurocognitive disorders in two different modalities: at the hospital and at home. Conducting a non-inferiority trial to verify the comparability of HomeCoRe with CoRe, and to provide further support for the use of HomeCoRe in distance treatment.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Anders Wimo, Ron Handels, Riitta Antikainen, Maria Eriksdotter, Linus Jonsson, Martin Knapp, Jenni Kulmala, Tiina Laatikainen, Jenni Lehtisalo, Markku Peltonen, Anders Skoldunger, Hilkka Soininen, Alina Solomon, Timo Strandberg, Jaakko Tuomilehto, Tiia Ngandu, Miia Kivipelto
Summary: This study estimated the potential cost-effectiveness of the FINGER program in Finland. The results showed that the FINGER program could save costs and improve quality-adjusted life years, supporting its effectiveness in preventing cognitive impairment and disability.
ALZHEIMERS & DEMENTIA
(2023)
Article
Economics
Joan Costa-Font, Martin Knapp, Cristina Vilaplana-Prieto
Summary: This study examines the impact of risk exposure to COVID-19 on the mental wellbeing effect of lockdowns and concludes that lockdown measures no longer reduce mental wellbeing in an environment of high mortality.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Psychiatry
Niklaus Stulz, Reto Joerg, Constanze Reim-Gautier, Charles Bonsack, Philippe Conus, Sara Evans-Lacko, Kerstin Gabriel-Felleiter, Eva Heim, Matthias Jaeger, Martin Knapp, Dirk Richter, Andres Schneeberger, Sir Graham Thornicroft, Rafael Traber, Simon Wieser, Alexandre Tuch, Urs Hepp
Summary: This study used small area analysis to identify health service areas for psychiatric outpatient care in Switzerland and found significant variation in the utilization of inpatient and outpatient services between these areas.
INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH
(2023)
Article
Psychology, Developmental
Mauricio Scopel Hoffmann, Sara Evans-Lacko, Stephan Collishaw, Martin Knapp, Andrew Pickles, Christina Shearer, Barbara Maughan
Summary: This study provides evidence on the long-term outcomes of both general and specific dimensions of adolescent psychopathology using parent and teacher reports. The general factors of psychopathology reported by parents and teachers were associated with various outcomes in socioeconomic, relationship, health, personality domains, as well as social exclusion. The specific factors reported by teachers were associated with more outcomes compared to those reported by parents.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Serena Sabatini, Anthony Martyr, Laura D. Gamble, Ian R. Jones, Rachel Collins, Fiona E. Matthews, Martin Knapp, Jeanette M. Thom, Catherine Henderson, Christina Victor, Claire Pentecost, Linda Clare, IDEAL Programme Team
Summary: This study describes the levels of social, cultural, and economic capital among people with dementia and examines the differences in personal characteristics and quality of life over time based on different combinations of capital. The results show that people with dementia have relatively lower levels of social, cultural, and economic capital, although they are not significantly lower compared to older adults in the UK. The study identifies four groups of people with dementia based on their capital levels and finds that higher levels of capital are associated with higher quality of life and well-being. Therefore, efforts from the government and society are needed to address the social, cultural, and economic disadvantages among people with dementia.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Geriatrics & Gerontology
E. V. Gerritzen, O. McDermott, M. Orrell
Summary: This study investigates the use of online peer support platforms by people with Young-Onset Dementia (YOD), the reasons for using or not using online peer support, and how to optimize its benefits and accessibility. A total of 69 completed surveys were analyzed, and it was found that Zoom is the most popular platform for online peer support, followed by Facebook and Twitter. While online peer support facilitates social support and accessibility, there are challenges related to following conversations and understanding others. Many individuals were unaware of online peer support and felt uncomfortable talking to strangers. To improve access and benefits, organizations and healthcare professionals should increase awareness and provide clear descriptions of online support groups.
AGING & MENTAL HEALTH
(2023)
Article
Cardiac & Cardiovascular Systems
Celine El Baou, Roopal Desai, Claudia Cooper, Natalie L. Marchant, Steve Pilling, Marcus Richards, Rob Saunders, Joshua E. J. Buckman, Elisa Aguirre, Amber John, Joshua Stott
Summary: This study aims to examine the association between psychotherapy outcomes for depression and incident cardiovascular disease (CVD). Through the analysis of national healthcare data in England, the study found that reliable improvement from depression symptoms through psychotherapy was associated with a lower risk of new onset of CVD.
EUROPEAN HEART JOURNAL
(2023)
Article
Gerontology
Linda Birt, Georgina Charlesworth, Esme Moniz-Cook, Phuong Leung, Paul Higgs, Martin Orrell, Fiona Poland
Summary: This study examines how people living with dementia maintain social interactions in their local communities through observations in community spaces. The findings indicate that individuals with dementia construct narratives and use strategies to assert their presence in social settings, drawing on personal attributes and familiar rituals.
Article
Gerontology
Yingyang Zhang, Hao Luo, Terry Y. S. Lum, Martin Knapp, Davide L. Vetrano, Celine C. S. Chui, Pengcheng Wang, Gloria H. Y. Wong
Summary: Evidence on healthcare utilization associated with comorbidity in people with dementia is lacking in Chinese societies. This population-based cohort study in Hong Kong aimed to quantify healthcare utilization among individuals with dementia and comorbid conditions. The study found that individuals with multiple comorbid chronic conditions had higher hospitalization and Accident and Emergency department visit rates. The presence of specific comorbid conditions, such as chronic kidney diseases and chronic ulcer of the skin, further increased the healthcare utilization rates. These findings emphasize the importance of considering multiple long-term conditions in providing tailored care for individuals with dementia.
DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE
(2023)
Article
Health Care Sciences & Services
Bryony Waters, Martin Orrell, Orii McDermott
Summary: This study aims to investigate the appropriateness of the adapted UK manual for UK care homes and to explore the effects on residents' music engagement, staff's dementia competence, residents' quality of life, and staff burden. This study is significant in improving the interaction quality between care home staff and residents with dementia.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Health Care Sciences & Services
Abigail Rebecca Lee, Emese Csipke, Lauren Yates, Esme Moniz-Cook, Orii McDermott, Steven Taylor, Michael Stephens, Daniel Kelleher, Martin Orrell
Summary: This study aimed to develop a web-based PRIDE manual. Through a lengthy development process, modifications were made to areas such as the log-in process and content layout. Feedback from the target population was incorporated into the process to make the PRIDE app more suitable for people with dementia. The finished version will be tested and further developed based on feedback gathered during the study.
JMIR HUMAN FACTORS
(2023)
Article
Geriatrics & Gerontology
Maximilian Salcher-Konrad, Cheng Shi, Disha Patel, David McDaid, Claudia Iveth Astudillo-Garcia, Kirsten Bobrow, Jacky Choy, Adelina Comas-Herrera, Andra Fry, Martin Knapp, Dara Kiu Yi Leung, Mariana Lopez-Ortega, Klara Lorenz-Dant, Christine Musyimi, David Ndetei, Tuan Anh Nguyen, Deborah Oliveira, Aditya Putra, Alisha Vara, Gloria Wong, Huseyin Naci, STRiDE Evidence Review Grp
Summary: This study aimed to systematically map the available evidence on dementia interventions in low- and middle-income countries (LMICs) to improve the lives of people with dementia or mild cognitive impairment (MCI) and/or their carers. The study found that the research on interventions for dementia in LMICs is concentrated in a few countries, with a skewed selection of interventions and a high risk of bias.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2023)
Article
Psychiatry
Maria A. Mendez, Roberto Canitano, Bethany Oakley, Antonia San Jose-Caceres, Michela Tinelli, Martin Knapp, James Cusack, Mara Parellada, Pierre Violland, Jan Derk R. Plas, Declan G. M. Murphy, Vinciane Quoidbach, Celso Arango
Summary: This study analyzed the care pathway for autistic children with co-occurring epilepsy in Italy, Spain, and the United Kingdom. The findings showed a lack of systematic screening and treatment of epilepsy, as well as inappropriate use of antiepileptic drugs. The major challenge is the lack of evidence-based guidelines for autism with co-occurring epilepsy in these countries. The study calls for policy harmonization in Europe to improve the experiences and quality of life of autistic individuals and their families.
EUROPEAN PSYCHIATRY
(2023)
Article
Psychiatry
Judit Simon, Patrice Boyer, Jose M. Caldas-de-Almeida, Martin Knapp, Paul McCrone, Philip Gorwood, Wolfgang Oertel, Celso Arango, Janet Treasure, Allan H. Young, Frederic Destrebecq, Vinciane Quoidbach
Summary: One in eight individuals worldwide and one in four individuals in many European countries have mental health problems. Three-quarters of mental health disorders develop before age 25, with undiagnosed symptoms often presenting in the mid-teens and lasting into old age. Evidence suggests that people frequently have multiple mental health disorders.
EUROPEAN PSYCHIATRY
(2023)
Article
Psychiatry
Maria A. Mendez, Bethany Oakley, Roberto Canitano, Antonia San Jose-Caceres, Michela Tinelli, Martin Knapp, James Cusack, Mara Parellada, Pierre Violland, Jan R. Derk Plas, Ricardo Canal-Bedia, Alvaro Bejarano-Martin, Declan G. M. Murphy, Vinciane Quoidbach, Celso Arango
Summary: There is a lack of harmonized guidelines in Europe for early detection, diagnosis, and intervention for autism, leading to unsatisfactory experiences for autistic individuals and their caregivers. The analysis of care pathways in Italy, Spain, and the UK revealed long wait times for screening and diagnosis, limited information and support, and deficient family support throughout the journey.
EUROPEAN PSYCHIATRY
(2023)
