Article
Behavioral Sciences
Lachlan Pettit, Georgia Ward-Fear, Richard Shine
Summary: In eastern Australia, the invasion of cane toads has altered the cognitive phenotype of giant monitor lizards, leading to lower success rates and slower speeds in completing tasks for lizards from sites colonized for a longer period by the toads. This suggests that toad-induced selection can impact cognitive performance in native species, with potential effects on other species within the ecosystem.
BEHAVIORAL ECOLOGY AND SOCIOBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Lachlan Pettit, Mathew S. Crowther, Georgia Ward-Fear, Richard Shine
Summary: This study found that the invasion of cane toads had different effects on the population of giant monitor lizards in Australia, possibly due to differences in food resource availability in different regions. Additionally, anthropogenically-induced changes to natural ecosystems may produce synergistic effects, intensifying their impacts.
Article
Biochemistry & Molecular Biology
Shabnam Mohammadi, Lu Yang, Arbel Harpak, Santiago Herrera-Alvarez, Maria del Pilar Rodriguez-Ordonez, Julie Peng, Karen Zhang, Jay F. Storz, Susanne Dobler, Andrew J. Crawford, Peter Andolfatto
Summary: This study reveals the evolutionary process of a tandem duplication of Na+,K+-ATPase subunit alpha 1 shared by frogs in the genus Leptodaclylus, with one paralog evolving resistance to toad toxins while the other retaining susceptibility. Frequent non-allelic gene conversion homogenized most of the sequence betwee the two copies, yet strong selection on 12 amino acid substitutions distinguished the two paralogs.
Article
Agriculture, Dairy & Animal Science
G. M. Bucciarelli, Farid Alsalek, L. B. Kats, D. B. Green, H. B. Shaffer
Summary: Toxin evolution in animals is a complex and fascinating area of scientific research. Understanding the factors that influence toxin evolution, such as genetics and ecology, as well as antagonistic interactions and coevolutionary dynamics, is crucial. By studying toxic Pacific newts and their coevolution with snake predators, we can gain insights into the evolution and ecology of toxins.
ANNUAL REVIEW OF ANIMAL BIOSCIENCES
(2022)
Article
Clinical Neurology
Daniel G. Calame, Cristina Moreno Vadillo, Seth Berger, Timothy Lotze, Marwan Shinawi, Javaher Poupak, Corina Heller, Julie Cohen, Richard Person, Aida Telegrafi, Chalongchai Phitsanuwong, Kaylene Fiala, Isabelle Thiffault, Florencia Del Viso, Dihong Zhou, Emily A. Fleming, Tomi Pastinen, Ali Fatemi, Sruthi Thomas, Samuel Pascual, Rosa J. Torres, Carmen Prior, Clara Gomez-Gonzalez, Saskia Biskup, James R. Lupski, Dragan Maric, Miguel Holmgren, Debra Regier, Sho T. Yano
Summary: Calame et al. report that genetic disorders of ATP1A3 can cause spasticity resembling cerebral palsy. They identify a genetic variant that leads to leakage of ions through the sodium-potassium pump and suggest it as a potential rare cause of spastic paraparesis. This study highlights the importance of ATP1A3 in neurological syndromes and provides insight into the molecular basis of phenotypic variability.
Article
Fisheries
Michael McGowan, Simon MacKenzie, Nikos Steiropoulos, Manfred Weidmann
Summary: The study tested the efficiency of a qRT-PCR assay for NKA alpha 1a mRNA in assessing seawater readiness of freshwater salmon smolts. The results showed high sensitivity in both lab and mobile assays, with indications of obscured results due to environmental heavy metal contamination.
Article
Agriculture, Multidisciplinary
Jinghua Zhu, Zengxin Li, Meng Zhang, Weiwei Qin, Yoonseong Park, Yueping He
Summary: This study utilized RNA-seq to identify a set of transporter and receptor genes enriched in the excretory organs of the brown planthopper (BPH). RNA interference assays showed that the knockdown of certain genes significantly affected the survival and honeydew secretion of BPH. These genes may serve as potential targets for insect control.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Fisheries
Reem Rida, Razan Zein-Eddine, Sawsan Kreydiyyeh, Antonio Garza de Yta, Imad Patrick Saoud
Summary: This study evaluated the effects of different salinities on the survival, growth, and osmoregulation in redclaw crayfish. The results showed that as salinity increased, the growth rate of redclaw crayfish decreased while sodium potassium ATPase activity and sodium potassium chloride cotransporter expression increased.
JOURNAL OF THE WORLD AQUACULTURE SOCIETY
(2021)
Article
Biochemistry & Molecular Biology
Patricia L. L. Jones, Kyle R. R. Martin, Sejal V. V. Prachand, Amy P. P. Hastings, Christophe Duplais, Anurag A. A. Agrawal
Summary: Plant secondary metabolites that defend leaves from herbivores also occur in floral nectar, but social insect pollinators are not expected to be as resistant to these compounds as specialist herbivores.
JOURNAL OF CHEMICAL ECOLOGY
(2023)
Article
Fisheries
Yating Mou, Bing Li, Yiran Hou, Rui Jia, Jian Zhu
Summary: This study investigated the response mechanism of fish to chronic H2O2 exposure and found that it causes incomplete gill structure, decreases potassium concentration while increasing sodium concentration in the plasma, and raises calcium level but decreases potassium and chlorine levels in the gills. Moreover, H2O2 exposure activates the calcium signaling pathway and affects the expression levels of ion-regulation-related genes. Overall, chronic H2O2 exposure alters gill structure, disturbs ion transport, and negatively affects ion equilibrium and osmotic pressure.
Article
Medicine, Research & Experimental
Elisabeth Petter, Carmen Scheibenbogen, Peter Linz, Christian Stehning, Klaus Wirth, Titus Kuehne, Marcus Kelm
Summary: This study found that muscle sodium content in patients with ME/CFS was higher than in healthy controls before and after exercise. Furthermore, there was an inverse correlation between muscle sodium content and handgrip strength. These findings suggest that sodium overload may play a role in the pathophysiology of ME/CFS and could be a potential therapeutic target.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Medicine, Research & Experimental
George J. Dugbartey
Summary: Hydrogen sulfide (H2S), previously recognized as a toxic gas, has now been acknowledged as an endogenously produced gaseous signaling molecule with diverse physiological and pathological functions at low concentrations. This review focuses on the renal production and functions of H2S, as well as its potential as a targeted therapeutic agent for renal pathologies such as hypertensive nephropathy, diabetic kidney disease, and water balance disorders.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Cell Biology
Kelath Murali Manoj, Daniel A. A. Gideon, Nikolai M. M. Bazhin, Hirohisa Tamagawa, Vijay Nirusimhan, Mahendra Kavdia, Laurent Jaeken
Summary: The redox metabolic paradigm emphasizes the importance of diffusible reactive species (DRS), particularly oxygen-centric radicals, in physiology. This article focuses on the membrane protein Na,K-ATPase (NKA) and its role in neuro-cardio-musculo electrophysiology. Through analyzing diffusion, NKA's structural features, ion transport mechanisms, and inhibitory effects of various substances, a minimalist murburn model is proposed to explain the physiological inhibitory effects of different substances on cells.
JOURNAL OF CELLULAR PHYSIOLOGY
(2023)
Article
Fisheries
Ifrah Zaffar, Tincy Varghese, Subrata Dasgupta, Narottam Prasad Sahu, Prem Prakash Srivastava, Vungarala Harikrishna, Zahoor Mushtaq, Showkat Ahmad Dar, Satya Prakash, Gopal Krishna
Summary: The study demonstrated that dietary potassium supplementation can partially or fully enhance the survival rate and ion balance of P. vannamei under inland saline water conditions. Compared to groups supplemented with feed potassium alone, the groups with potassium fortified ISW could more effectively enhance HSP protection.
AQUACULTURE RESEARCH
(2021)
Article
Biotechnology & Applied Microbiology
Andrew J. Mongue, Simon H. Martin, Rachel E. V. Manweiler, Helena Scullion, Jordyn L. Koehn, Jacobus C. de Roode, James R. Walters
Summary: By sequencing the genome of a parasite that infects monarch butterflies, we gained insights into the evolution and diversity of Apicomplexa. The genome of the parasite was found to be very small, containing fewer genes compared to other invertebrate-infecting apicomplexans. Additionally, we discovered different orthologs shared by different parasites, suggesting a limited set of universally conserved apicomplexan genes. Furthermore, we identified a highly diverged parasite genome in another butterfly, potentially indicating a distinct species.
Review
Biochemistry & Molecular Biology
Justine Boutry, Sophie Tissot, Beata Ujvari, Jean-Pascal Capp, Mathieu Giraudeau, Aurora M. Nedelcu, Frederic Thomas
Summary: Tumors are usually classified as benign or malignant, but the mechanistic distinction has limited our understanding of the neoplastic process. Recognizing the differences and similarities between benign and malignant tumors is crucial for understanding malignancy.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
(2022)
Article
Anesthesiology
Jens T. F. Osterkamp, Rune B. Strandby, Lara Henningsen, Klaus Marcussen, Thordis Thomsen, Christian R. Mortensen, Michael P. Achiam, Oivind Jans
Summary: This study compared the effects of intermittent mask CPAP (ICPAP) and continuous helmet CPAP (HCPAP) on oxygenation and the risk of pulmonary complications following major abdominal surgery. The results showed that there were no significant differences in oxygenation and the risk of pulmonary complications between the two treatment methods, but continuous helmet CPAP treatment may lead to a higher sensation of claustrophobia.
JOURNAL OF CLINICAL MONITORING AND COMPUTING
(2023)
Editorial Material
Obstetrics & Gynecology
Stephen J. Simpson, David Raubenheimer, Kirsten I. Black, Arthur D. Conigrave
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Surgery
Jens Osterkamp, Rune Strandby, Nikolaj Nerup, Morten-Bo Svendsen, Lars-Bo Svendsen, Michael Achiam
Summary: This study investigated the use of intraoperative ICG lymphography in robot-assisted resection of GEJ cancer. The results showed that this technique could aid in LN detection without increasing surgical risk. However, none of the dissected LNs were found to be metastatic. Therefore, the potential improvement in oncological outcomes with NIR lymphography remains uncertain.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Ecology
Thomas Madsen, Beata Ujvari, Dirk Bauwens, Bernd Gruber, Arthur Georges, Marcel Klaassen
Summary: According to conservation genetic theory, small and isolated populations should have reduced genetic diversity. However, our long-term study of an isolated island population of adders in Sweden challenges this notion. Despite a lack of gene flow and a small population size, the adders on the island maintain high levels of genetic diversity. The presence of polyandry and non-random fertilization in female adders seems to be responsible for this maintenance.
Article
Evolutionary Biology
Antoine M. Dujon, Aurelie Tasiemski, Pascal Pujol, Anthony Turpin, Beata Ujvari, Frederic Thomas
Summary: The origin of why humans historically started using spices in their diets is still debated. While there is evidence of spices having anticancer effects, our findings suggest that spice consumption is not related to the prevalence of gastrointestinal cancers in 36 countries. This indicates that there may be other factors influencing the preference for spices in our ancestors.
EVOLUTION MEDICINE AND PUBLIC HEALTH
(2023)
Article
Ecology
Margaux Bieuville, Dominique Faugere, Virginie Galibert, Morgane Henard, Antoine M. Dujon, Beata Ujvari, Pascal Pujol, Benjamin Roche, Frederic Thomas
Summary: It is believed that evolutionary mismatches contribute to human susceptibility to cancer, as our ancestors developed cancer suppression mechanisms in different environments. Reproductive traits have been shown to modulate breast cancer risk in Western populations. This study investigates whether reproductive patterns also affect breast cancer risk in menopausal women at high familial risk. The results suggest that the total number of menses is significantly associated with postmenopausal breast cancer risk and influences the time of onset. These findings impact breast cancer prevention strategies and call for further research on ecological and genetic factors.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2023)
Article
Evolutionary Biology
Thomas Madsen, Jon Loman, Dirk Bauwens, Bo Stille, Hakan Anderberg, Lewis Anderberg, Beata Ujvari
Summary: In southern Sweden, an isolated adder population experienced a significant decline in body mass and a 50% reduction in population size due to the exceptionally hot and dry summer of 2018. This study highlights the detrimental effects of climate change on vertebrate populations and underscores the need for long-term studies to assess the demographic impacts of extreme climatic events.
BIOLOGICAL JOURNAL OF THE LINNEAN SOCIETY
(2023)
Article
Evolutionary Biology
Rodrigo Hamede, Nicholas M. Fountain-Jones, Fernando Arce, Menna Jones, Andrew Storfer, Paul A. Hohenlohe, Hamish McCallum, Benjamin Roche, Beata Ujvari, Frederic Thomas
Summary: Infectious diseases pose a major threat to biodiversity conservation and wildlife population dynamics. The use of phylodynamics, which combines pathogen evolutionary processes with epidemiological dynamics, can provide valuable insights into disease control strategies. This study examines the role of tumour genetic diversity in the epidemiological and population dynamics of devil facial tumour disease (DFTD) in Tasmanian devils.
EVOLUTIONARY APPLICATIONS
(2023)
Editorial Material
Endocrinology & Metabolism
Arthur D. Conigrave, Stephen J. Simpson
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Multidisciplinary Sciences
Justine Boutry, Marie Buysse, Sophie Tissot, Chantal Cazevielle, Rodrigo Hamede, Antoine M. Dujon, Beata Ujvari, Mathieu Giraudeau, Alexander Klimovich, Frederic Thomas, Jacint Tokolyi
Summary: This study investigates the diversity of tumors found in freshwater cnidarians called hydras, specifically looking at different sexes and geographical origins. The study also identifies a unique microbiota associated with these tumors, providing new insights into the understanding of tumor susceptibility and diversity in hydras.
SCIENTIFIC REPORTS
(2023)
Article
Ecology
Badreddine Bererhi, Pierre Duchesne, Tonia S. Schwartz, Beata Ujvari, Erik Wapstra, Mats Olsson
Summary: The harmful effects of close inbreeding have been recognized for centuries and are caused by homozygosis. This study investigates the effects of genetic relatedness on pair formation in sand lizards. The results suggest that MHC plays a role in pre-copulatory, but not post-copulatory partner association, indicating that MHC is not the driver of fertilization bias and gamete recognition in sand lizards.
ECOLOGY AND EVOLUTION
(2023)
Review
Evolutionary Biology
Jean-Pascal Capp, Frederic Thomas, Andriy Marusyk, Antoine M. Dujon, Sophie Tissot, Robert Gatenby, Benjamin Roche, Beata Ujvari, James DeGregori, Joel S. Brown, Aurora M. Nedelcu
Summary: It is traditionally assumed that cancer cells become selfish and cooperate only to enhance their own fitness, but recent research suggests that they can also cooperate with other cancer cells and stromal cells. The reasons behind this paradox and the possible mechanisms for this cooperation are not fully understood.
EVOLUTIONARY APPLICATIONS
(2023)
Article
Biology
Antoine M. Dujon, Orsolya Vincze, Jean-Francois Lemaitre, Catherine Alix-Panabieres, Pascal Pujol, Mathieu Giraudeau, Beata Ujvari, Frederic Thomas
Summary: Reproduction is a central activity for all living organisms but has various costs that can be detrimental for survival. A recent study investigated the cost of cancer as a selective force and found that cancer mortality was more likely to be detected in mammal species with larger litter sizes and longer lactation lengths. However, these factors alone did not increase the risk of cancer mortality. Surprisingly, species with moderately invasive placentation had the highest cancer mortality rates. This study suggests that high reproductive efforts and the evolution of placentation have implications for the development of cancer.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2023)
Review
Surgery
P. van Den Hoven, J. Osterkamp, N. Nerup, M. B. S. Svendsen, Alexander Vahrmeijer, J. R. van der Vorst, M. P. Achiam
Summary: Incorrect assessment of tissue perfusion carries a significant risk of complications in surgery. The use of near-infrared (NIR) fluorescence imaging with Indocyanine Green (ICG) presents a possible solution. This review provides an overview of quantification methods for perfusion assessment using ICG NIR fluorescence imaging, highlighting the need for standardization of quantification methods in order to improve reliability.
LANGENBECKS ARCHIVES OF SURGERY
(2023)