期刊
EUROSURVEILLANCE
卷 19, 期 44, 页码 7-9出版社
EUR CENTRE DIS PREVENTION & CONTROL
DOI: 10.2807/1560-7917.ES2014.19.44.20951
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资金
- Institut de Veille Sanitaire (St. Maurice, France)
We report the first case in France of a high-level azithromycin- resistant Neisseria gonorrhoeae (minimum inhibitory concentration (MIC) = 96 mg/L) assigned to MLST7363 (NG-MAST ST6360), also resistant to ciprofloxacin and tetracycline but susceptible to ceftriax-one. The patient was a 51 year-old heterosexual man who returned following 1g azithromycin monotherapy. Mechanisms of azithromycin resistance were a C2599T mutation in the four copies of the rrl gene and a novel mutation in the promoter of the mtrR gene.
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