Detection of TDP-43 oligomers in frontotemporal lobar degeneration-TDP

Therapeutic approaches against common structural features of toxic oligomers shared by multiple amyloidogenic proteins

(2014) Marcos J. Guerrero-Muñoz et al.   BIOCHEMICAL PHARMACOLOGY

Hippocampal sclerosis dementia with the C9ORF72 hexanucleotide repeat expansion

(2014) Olga Pletnikova et al.   NEUROBIOLOGY OF AGING

Significance and limitation of the pathological classification of TDP-43 proteinopathy

(2014) Tetsuaki Arai   NEUROPATHOLOGY

Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

(2014) Yu-Sheng Fang et al.   Nature Communications

A case of familial ALS due to multi-system proteinopathy 1 and Huntington disease

(2014) Björn Oskarsson et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

TDP-43 deposition in prospectively followed, cognitively normal elderly individuals: correlation with argyrophilic grains but not other concomitant pathologies

(2013) Stacy J. Arnold et al.   ACTA NEUROPATHOLOGICA

Staging TDP-43 pathology in Alzheimer’s disease

(2013) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function

(2013) Chung-ke Chang et al.   FEBS LETTERS

Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion

(2013) Lei-Lei Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aberrant Assembly of RNA Recognition Motif 1 Links to Pathogenic Conversion of TAR DNA-binding Protein of 43 kDa (TDP-43)

(2013) Akemi Shodai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Truncated C-terminal RNA Recognition Motif of TDP-43 Protein Plays a Key Role in Forming Proteinaceous Aggregates

(2013) Yi-Ting Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases

(2013) Steven E. Arnold et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Reducing TDP-43 aggregation does not prevent its cytotoxicity

(2013) Rui Liu et al.   Acta Neuropathologica Communications

p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS

(2011) Safa Al-Sarraj et al.   ACTA NEUROPATHOLOGICA

A harmonized classification system for FTLD-TDP pathology

(2011) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration

(2011) Fabienne C. Fiesel et al.   FEBS Journal

Phosphorylated TDP-43 pathology and hippocampal sclerosis in progressive supranuclear palsy

(2010) Osamu Yokota et al.   ACTA NEUROPATHOLOGICA

Increased neuronal Rab5 immunoreactive endosomes do not colocalize with TDP-43 in motor neuron disease

(2010) Radoslav Matej et al.   EXPERIMENTAL NEUROLOGY

TAR DNA-binding protein 43 in neurodegenerative disease

(2010) Alice S. Chen-Plotkin et al.   Nature Reviews Neurology

Evaluation of subcortical pathology and clinical correlations in FTLD-U subtypes

(2009) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Structural insights into TDP-43 in nucleic-acid binding and domain interactions

(2009) P.-H. Kuo et al.   NUCLEIC ACIDS RESEARCH

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

(2009) Y.-J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases

(2008) Wen-Lang Lin et al.   ACTA NEUROPATHOLOGICA

Electrodiagnostic criteria for diagnosis of ALS

(2008) Mamede de Carvalho et al.   CLINICAL NEUROPHYSIOLOGY

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

(2008) I.-Fan Wang et al.   JOURNAL OF NEUROCHEMISTRY

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

(2008) B. S. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TDP-43: an emerging new player in neurodegenerative diseases

(2008) I-Fan Wang et al.   TRENDS IN MOLECULAR MEDICINE

Neuropathological basis of magnetic resonance images in aging and dementia

(2007) William J. Jagust et al.   ANNALS OF NEUROLOGY

Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease

(2007) Emanuele Buratti   Frontiers in Bioscience-Landmark