Disc cell therapy with bone-marrow-derived autologous mesenchymal stromal cells in a large porcine disc degeneration model

Repairing the ruptured annular fibrosus by using type I collagen combined with citric acid, EDC and NHS: an in vivo study

(2016) Yan Wang et al.   EUROPEAN SPINE JOURNAL

The aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae

(2016) Danielle M. Stewart et al.   EUROPEAN SPINE JOURNAL

Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study

(2016) Christian Elabd et al.   Journal of Translational Medicine

Stem cells sources for intervertebral disc regeneration

(2016) Gianluca Vadalà et al.   World Journal of Stem Cells

Intervertebral disc degenerative changes after intradiscal injection of TNF-α in a porcine model

(2015) Ran Kang et al.   EUROPEAN SPINE JOURNAL

Efficacy of intervertebral disc regeneration with stem cells — A systematic review and meta-analysis of animal controlled trials

(2015) Zhen Wang et al.   GENE

Inflammation in intervertebral disc degeneration and regeneration

(2015) M. Molinos et al.   Journal of the Royal Society Interface

Stem cell therapy for intervertebral disc regeneration: obstacles and solutions

(2015) Daisuke Sakai et al.   Nature Reviews Rheumatology

Stem Cell Approaches to Intervertebral Disc Regeneration: Obstacles from the Disc Microenvironment

(2015) Feng Wang et al.   STEM CELLS AND DEVELOPMENT

MRI T2* mapping correlates with biochemistry and histology in intervertebral disc degeneration in a large animal model

(2014) Suzanne E. L. Detiger et al.   EUROPEAN SPINE JOURNAL

Mesenchymal Stem Cells Reduce Intervertebral Disc Fibrosis and Facilitate Repair

(2014) Victor Y.L. Leung et al.   STEM CELLS

In vivo biofunctional evaluation of hydrogels for disc regeneration

(2013) Sandra Reitmaier et al.   EUROPEAN SPINE JOURNAL

Injection of a polymerized hyaluronic acid/collagen hydrogel matrix in an in vivo porcine disc degeneration model

(2012) G. W. Omlor et al.   EUROPEAN SPINE JOURNAL

Mesenchymal stem cells injection in degenerated intervertebral disc: cell leakage may induce osteophyte formation

(2011) Gianluca Vadalà et al.   Journal of Tissue Engineering and Regenerative Medicine

Investigation of different cell types and gel carriers for cell-based intervertebral disc therapy,in vitroandin vivostudies

(2011) H. B. Henriksson et al.   Journal of Tissue Engineering and Regenerative Medicine

Reduced Reactivation from Dormancy but Maintained Lineage Choice of Human Mesenchymal Stem Cells with Donor Age

(2011) Verena Dexheimer et al.   PLoS One

Biological and Biomechanical Effects of Fibrin Injection Into Porcine Intervertebral Discs

(2011) Zorica Buser et al.   SPINE

Porcine Intervertebral Disc Repair Using Allogeneic Juvenile Articular Chondrocytes or Mesenchymal Stem Cells

(2011) Frank L. Acosta et al.   TISSUE ENGINEERING PART A

Intervertebral disc regeneration after implantation of a cell-free bioresorbable implant in a rabbit disc degeneration model

(2010) Michaela Endres et al.   BIOMATERIALS

Degeneration and regeneration of the intervertebral disc: lessons from development

(2010) L. J. Smith et al.   Disease Models & Mechanisms

Immunohistochemical identification of notochordal markers in cells in the aging human lumbar intervertebral disc

(2010) Christoph Weiler et al.   EUROPEAN SPINE JOURNAL

Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model

(2010) Kenji Serigano et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Transplantation of Goat Bone Marrow Stromal Cells to the Degenerating Intervertebral Discin a Goat Disc Injury Model

(2010) Yejia Zhang et al.   SPINE

Transplanted mesenchymal stem cells with pure fibrinous gelatin-transforming growth factor-β1 decrease rabbit intervertebral disc degeneration

(2010) Huilin Yang et al.   Spine Journal

Metalloproteinases and their inhibitors—diagnostic and therapeutic opportunities in orthopedics

(2009) Björn Pasternak et al.   Acta Orthopaedica

Human mesenchymal stem cells implantation into the degenerated coccygeal disc of the rat

(2009) Je Hoon Jeong et al.   CYTOTECHNOLOGY

Methods to monitor distribution and metabolic activity of mesenchymal stem cells following in vivo injection into nucleotomized porcine intervertebral discs

(2009) G. W. Omlor et al.   EUROPEAN SPINE JOURNAL

Mesenchymal stem cells in regenerative medicine: Opportunities and challenges for articular cartilage and intervertebral disc tissue engineering

(2009) Stephen M. Richardson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mesenchymal Stem Cells Arrest Intervertebral Disc Degeneration Through Chondrocytic Differentiation and Stimulation of Endogenous Cells

(2009) Fan Yang et al.   MOLECULAR THERAPY

Transplantation of Human Mesenchymal Stems Cells Into Intervertebral Discs in a Xenogeneic Porcine Model

(2009) Helena B. Henriksson et al.   SPINE

A New Porcine In Vivo Animal Model of Disc Degeneration

(2009) Georg W. Omlor et al.   SPINE

Matrix Metalloprotease Inhibitors Suppress Initiation and Progression of Chondrogenic Differentiation of Mesenchymal Stromal Cells In Vitro

(2009) Helge Bertram et al.   STEM CELLS AND DEVELOPMENT

Effect of Severity of Intervertebral Disc Injury on Mesenchymal Stem Cell-Based Regeneration

(2008) Grace Ho et al.   CONNECTIVE TISSUE RESEARCH

Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: Implications for disk degeneration and chordoma formation

(2008) Kyung-Suk Choi et al.   DEVELOPMENTAL DYNAMICS

Transplantation of mesenchymal stem cells in a canine disc degeneration model

(2008) Akihiko Hiyama et al.   JOURNAL OF ORTHOPAEDIC RESEARCH