Review
Clinical Neurology
Ram Alluri, Jung Kee Mok, Avani Vaishnav, Tara Shelby, Ahilan Sivaganesan, Raymond Hah, Sheeraz A. Qureshi
Summary: The effectiveness of using EMG, MEP, and SSEP for intraoperative neuromonitoring during lateral lumbar interbody fusion is controversial, but multimodal IONM strategies may reduce postoperative neurologic injuries.
Article
Orthopedics
Cheng-Min Shih, Cheng-En Hsu, Kun-Hui Chen, Chien-Chou Pan, Cheng-Hung Lee
Summary: This study investigated the surgical outcomes and prognostic factors of anterior lumbar interbody fusion (ALIF) in revision lumbar interbody fusion. The results showed that ALIF achieved positive clinical and radiographic results in revision lumbar fusion surgery. However, having two or more preoperative fusion segments negatively impacted back pain improvement reaching the minimum clinically important difference (MCID).
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Clinical Neurology
Austin Q. Nguyen, Jackson P. Harvey, Krishn Khanna, Bryce A. Basques, Garrett K. Harada, Frank M. Phillips, Kern Singh, Christopher Dewald, Howard S. An, Matthew W. Colman
Summary: The reoperation rate after anterior or lateral lumbar interbody fusions without direct posterior decompression is low. Majority of same-level reoperations were due to a need for further decompression. Smaller preoperative canal diameters were associated with the need for revision decompression.
JOURNAL OF NEUROSURGERY-SPINE
(2021)
Review
Clinical Neurology
Dallas E. Kramer, Cody Woodhouse, Mena G. Kerolus, Alexander Yu
Summary: This is the first comprehensive study on the position of the lumbar plexus in lateral lumbar interbody fusion (LLIF), and it was found that the lumbar plexus is significantly displaced ventrally with the supine position compared to lateral decubitus position, and MRI may overestimate ventral encroachment of lumbar plexus.
EUROPEAN SPINE JOURNAL
(2022)
Article
Clinical Neurology
Justin W. Silverstein, Jon Block, Michael L. Smith, David A. Bomback, Scott Sanderson, Justin Paul, Hieu Ball, Jason A. Ellis, Matthew Goldstein, David L. Kramer, Grigoriy Arutyunyan, Joshua Marcus, Sara Mermelstein, Paul Slosar, Noel Goldthwaite, Sun Ik Lee, James Reynolds, Margaret Riordan, Nick Pirnia, Sandeep Kunwar, Gaurav Abbi, Bruce Bizzini, Sarita Gupta, Dorothy Porter, Laurence E. Mermelstein
Summary: Intraoperative femoral nerve monitoring can provide timely alerts to surgeons about the degradation of femoral nerve function, and prompt surgical countermeasures can mitigate or avoid nerve injuries. However, the common strategy of limiting retraction duration may not be effective.
Article
Clinical Neurology
Mohamed Macki, Travis Hamilton, Yazeed W. Haddad, Victor Chang
Summary: This literature review focuses on the indications, surgical techniques, and outcomes of expandable transforaminal lumbar interbody fusion (TLIF), anterior lumbar interbody fusion (ALIF), and lateral lumbar interbody fusion (LLIF) operations. The review discusses the nuances between expandable and static cages for all three TLIF, ALIF, and LLIF operations.
OPERATIVE NEUROSURGERY
(2021)
Article
Clinical Neurology
S. Harrison Farber, James J. Zhou, Michael A. Smith, Randall W. Porter, Steve W. Chang
Summary: This study evaluated the technical feasibility of performing minimally invasive anterolateral fixation in a single supine position. The results confirmed acceptable positioning of both ALIF and LLIF grafts with no observed injuries to the cadaveric peritoneum, vasculature, or lumbar plexus. This cadaveric feasibility study suggests that combined minimally invasive ALIF and LLIF may be performed as a single-stage procedure with the patient in the supine position, warranting further clinical consideration and study.
WORLD NEUROSURGERY
(2022)
Review
Clinical Neurology
Sven Bamps, Vincent Raymaekers, Gert Roosen, Eric Put, Steven Vanvolsem, Salah-Eddine Achahbar, Sacha Meeuws, Maarten Wissels, Mark Plazier
Summary: This systematic review compared the outcomes between lateral surgical approaches (LLIF/XLIF) and posterior interbody fusion surgery (PLIF) for degenerative lumbar diseases. The results showed that lateral approaches had less blood loss, shorter hospital stays, and comparable functional outcomes. Complication rates did not significantly differ between the two approaches. Therefore, lateral surgical approaches are a safe and effective alternative to PLIF.
WORLD NEUROSURGERY
(2023)
Article
Orthopedics
Kaihui Zhang, Haiwei Xu, Lilong Du, Yue Liu, Baoshan Xu
Summary: This study retrospectively evaluated the efficacy of self-anchored lateral lumbar interbody fusion (SA-LLIF) in lumbar degenerative diseases. The results showed that SA-LLIF can provide immediate stability, reduce pain, and improve quality of life with few surgical complications.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Orthopedics
Jia-Ming Cui, Jian-Ru Wang, Zhao-Min Zheng, Hui Liu, Hua Wang, Ze-Min Li
Summary: The mini-open LaLIF technique is a safe and reproducible method for lateral lumbar fusion, associated with reliable mid-term clinical outcomes and an acceptable complication profile. This technique utilizes modified incision site, direct visualization, and vertical trajectory with a specially designed system to achieve successful surgical results.
JOURNAL OF ORTHOPAEDIC TRANSLATION
(2021)
Article
Clinical Neurology
Kimberly Ashayeri, Carlos Leon, Seth Tigchelaar, Parastou Fatemi, Matt Follett, Ivan Cheng, J. Alex Thomas, Mark Medley, Brett Braly, Brian Kwon, Leon Eisen, Themistocles S. Protopsaltis, Aaron J. Buckland
Summary: The study compared the perioperative outcomes of lateral lumbar interbody fusion with traditional supine anterior lumbar interbody fusion for degenerative pathologies, showing that lateral lumbar interbody fusion led to improved operative time, estimated blood loss, length of stay, and reduced rate of ileus while maintaining safety.
Article
Clinical Neurology
Jiaming Cui, Xingyu Guo, Zhaomin Zheng, Hui Liu, Hua Wang, Zemin Li, Jianru Wang
Summary: The study investigated perioperative complications of lateral anterior lumbar interbody fusion (LaLIF) surgery in patients with degenerative lumbar diseases. The overall complication rate was low and transient, with temporary psoas injury being the most common intraoperative complication and cage migration being the most frequent postoperative complication. Adequate use of muscle relaxants, appropriate instruments, and vertical trajectories can help prevent severe complications in LaLIF surgery.
EUROPEAN SPINE JOURNAL
(2021)
Article
Orthopedics
Qing-Yi Zhang, Jie Tan, Kai Huang, Hui-Qi Xie
Summary: This study compared the clinical and radiographic efficacy of Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS-TLIF) and Oblique lateral Interbody Fusion (OLIF). The results showed that OLIF had shorter operation time, less intraoperative blood loss, better leg pain alleviation, disc height restoration, and subsidence resistance compared to MIS-TLIF. However, there were no significant differences in back pain relief, functional recovery, complications, disc angle restoration, lumbar lordosis restoration, and fusion rate between the two procedures. Further high-level studies are needed to confirm these findings.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Medicine, General & Internal
Quan-You Gao, Fei-Long Wei, Tian Li, Kai-Long Zhu, Ming-Rui Du, Wei Heng, Fan Yang, Hao-Ran Gao, Ji-Xian Qian, Cheng-Pei Zhou
Summary: This study compared the outcomes and complications of patients with lumbar spinal stenosis (LSS) undergoing oblique lateral interbody fusion (OLIF) or minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF). The results showed that OLIF and MIS-TLIF had similar postoperative improvements, but OLIF was more successful at restoring disc height, foraminal height, and lumbar lordotic angle. The complication rates were comparable between the two procedures.
FRONTIERS IN MEDICINE
(2022)
Review
Clinical Neurology
Armin Mortazavi, William Mualem, Ehsan Dowlati, Hepzibha Alexander, Juliana Rotter, Charles Withington, Marc Margolis, Jean-Marc Voyadzis
Summary: This study aimed to assess the complication rates after anterior lumbar interbody fusion (ALIF) and identify variables associated with postoperative complications. The results showed that 26.2% of patients experienced minor or major complications, with the most common ones being surgical site infections, neurological complications, vascular complications, and urinary tract infections. Patients with postoperative complications had higher mean age, higher BMI, higher ASA status, and higher estimated blood loss. Patients undergoing ALIF with posterior instrumentation and postoperative complications were more likely to have diabetes and had a higher ASA status. Patients with complications from both groups had longer length of stay, discharge to a non-home setting, and were more likely to be readmitted or return to the operating room.
Article
Orthopedics
Vincent J. Leopold, Adrian Szarek, Christian Hipfl, Matthias Pumberger, Carsten Perka, Sebastian Hardt, Jannis Loechel
Summary: This study aimed to determine the change in activity level after PAO by assessing the UCLA activity score and changes in qualitative and quantitative sports activity. The results showed that patients can improve their sports activity both qualitatively and quantitatively after PAO. However, a significant number of patients adjust their sports activities for various reasons.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2023)
Correction
Orthopedics
Friederike Schoemig, Yannick Palmowski, Florian Schitz
ZEITSCHRIFT FUR ORTHOPADIE UND UNFALLCHIRURGIE
(2023)
Article
Multidisciplinary Sciences
Luis Becker, Christian Hipfl, Friederike Schoemig, Carsten Perka, Sebastian Hardt, Matthias Pumberger, Vincent Justus Leopold
Summary: This study retrospectively examined the effects of LSTV on DDH patients and the surgical treatment through PAO. The study found that patients with LSTV had significantly higher posterior-wall-index, but no significant differences were seen in other indices. There were also no significant differences in patient-reported outcomes before and after surgery. Therefore, even patients with LSTV can achieve good outcomes with PAO.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Henryk Haffer, Zhouyang Hu, Zhen Wang, Maximilian Muellner, Sebastian Hardt, Matthias Pumberger
Summary: This study aimed to determine the influence of age on spinopelvic function in patients undergoing total hip arthroplasty (THA). The results showed that lumbar flexibility and pelvic mobility decreased with increasing age, leading to increased pelvic retroversion and global spinal imbalance. Older patients were identified as a high-risk group for abnormal spinopelvic function and limited improvement of mobility after THA.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Luis Becker, Friederike Schoemig, Lea Marie-Sophie Cordes, Georg N. Duda, Matthias Pumberger, Hendrik Schmidt
Summary: A study was conducted with 523 participants, including 120 with low back pain and 356 without symptoms. It was found that participants with low back pain had reduced pelvic and lumbar range of motion and increased finger-floor distance compared to the asymptomatic control group. Lumbar flexibility assessment should take into account the correlation of pelvic and lumbar motion.
Article
Medicine, General & Internal
Maximilian Muellner, Katharina Ziegeler, Torsten Diekhoff, Henryk Haffer, Friederike Schoemig, Vincent Justus Leopold, Matthias Pumberger, Friedemann Goehler
Summary: This study found a higher prevalence of osteitis condensans ilii (OCI) in patients with developmental dysplasia of the hip (DDH) compared to the general population, and BMI was shown to have an influence on the occurrence of OCI. OCI may be attributable to altered mechanical loading of the hip and sacroiliac joints. Clinicians should be aware of the common occurrence of OCI in DDH patients and its potential association with low back pain, lateral hip pain, and nonspecific hip or thigh pain.
Article
Clinical Neurology
Max J. Scheyerer, Max Lenz, Cornelius Jacobs, Matthias Pumberger, Ulrich J. A. Spiegl, Bernhard W. Ullrich, Nicolas von der Hoeh, Klaus John Schnake
Summary: This article studied the surgical treatment of osteoporotic vertebral compression fractures in elderly patients and found that factors such as age, gender, BMI, and physical condition are associated with complications, length of hospital stay, hospital mortality, and clinical outcomes. It is recommended to assess these factors before surgery and call for interdisciplinary cooperation.
GLOBAL SPINE JOURNAL
(2023)
Review
Clinical Neurology
Friederike Schoemig, Luis Becker, Lukas Schoennagel, Anna Voelker, Alexander C. Disch, Klaus John Schnake, Matthias Pumberger
Summary: With an aging population, the prevalence of osteoporosis is increasing. Osteoporosis has been shown to increase the risk of implant failure and reoperation rates in spine surgery patients. This review aims to provide evidence-based solutions for the surgical treatment of osteoporosis patients. The review summarizes the literature on bone mineral density changes and biomechanical implications for the spine, as well as multidisciplinary treatment strategies to avoid implant failures in osteoporotic patients.
GLOBAL SPINE JOURNAL
(2023)
Article
Clinical Neurology
Christian Herren, Nicolas Heinz von der Hoeh, Stefan Zwingenberger, Daniel Sauer, Norma Jung, Philipp Pieroh, Steffen Drange, Matthias J. Pumberger, Max Scheyerer
Summary: This review article aims to provide an overview of the treatment of pyogenic spondylodiscitis in geriatric patients, and offers recommendations on necessary diagnostics as well as conservative and operative treatment options. The systematic literature search conducted by the spondylodiscitis working group of the German Society for Orthopedics and Trauma Surgery reveals that the incidence of spondylodiscitis increases with age, peaking at 75 years or older. The 1-year mortality rate without appropriate treatment is extremely high, ranging from 15% to 20%.
GLOBAL SPINE JOURNAL
(2023)
Article
Clinical Neurology
Maximilian Muellner, Henryk Haffer, Manuel Moser, Krizia Amoroso, Zhaorui Wang, Artine Arzani, Ek T. T. Tan, Erika Chiapparelli, Yusuke Dodo, Jennifer Shue, Matthias Pumberger, Andrew A. A. Sama, Frank P. P. Cammisa, Federico P. P. Girardi, Alexander P. P. Hughes
Summary: This study aimed to investigate the changes of posterior paraspinal muscles and psoas muscle in patients with low back pain over time. MRI-based quantitative assessments were conducted to calculate various muscle parameters. The results showed that the functional cross sectional area of the posterior paraspinal muscles decreased and the fat area increased in only three years, with higher fat infiltration in females.
EUROPEAN SPINE JOURNAL
(2023)
Article
Multidisciplinary Sciences
Ping Shen, Sebastian Serve, Peihua Wu, Xiaohui Liu, Yujie Dai, Nayar Duran-Hernandez, Dan Thi Mai Nguyen, Michael Fuchs, Tazio Maleitzke, Marie-Jacqueline Reisener, Maria Dzamukova, Katrin Nussbaumer, Tobias M. Brunner, Yonghai Li, Vivien Holecska, Gitta A. Heinz, Frederik Heinrich, Pawel Durek, Georgia Katsoula, Clemens Gwinner, Tobias Jung, Eleftheria Zeggini, Tobias Winkler, Mir-Farzin Mashreghi, Matthias Pumberger, Carsten Perka, Max Lohning
Summary: TLR2 stimulation suppresses matrix protein expression and induces an inflammatory phenotype in chondrocytes, while also impairing mitochondrial function and reducing ATP production. The study also shows that inhibiting NOS2 can restore mitochondrial function and protect against age-related OA development.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Medicine, General & Internal
Vincent Justus Leopold, Christian Hipfl, Robert Karl Zahn, Matthias Pumberger, Carsten Perka, Sebastian Hardt
Summary: Periacetabular osteotomy with K-wire fixation technique provides good clinical outcomes at mid-term follow-up, comparable to those of screw fixation technique.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Orthopedics
Vincent J. Leopold, Nikolas Warminski, Jannis Loechel, Kirsten Labbus, Matthias Pumberger, Robert K. Zahn
Summary: The present study aimed to evaluate a novel single-item score, the Subjective Spine Value (SSpV), for assessing spinal function. The study found that SSpV was significantly correlated with the established scores ODI and COMI, indicating that SSpV is a valid tool for assessing spinal function.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Article
Orthopedics
Christian Hipfl, Vincent Leopold, Luis Becker, Matthias Pumberger, Carsten Perka, Sebastian Hardt
Summary: This study compares the outcomes of two-stage revision for chronic periprosthetic joint infection (PJI) in cemented and cementless total hip arthroplasty (THA). The results show that patients with cemented THA have more severe femoral bone loss, a higher risk of positive cultures during reimplantation, higher rates of reinfection, and all-cause revision compared to patients with cementless THA. Femoral fractures were also more frequent in patients with prior cementation.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Article
Orthopedics
Friederike Schoemig, Nima Taheri, Hussein Kalaf, Maximilian Muellner, Luis Becker, Matthias Pumberger
Summary: This study aimed to evaluate the validity and reliability of classification and severity score systems for thoracolumbar fractures in pediatric patients. The results showed that TLICS was a valid classification system for determining treatment decisions in pediatric patients, and the AOSpine injury score showed higher accuracy. Both classification systems demonstrated high interrater reliability.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)