Article
Radiology, Nuclear Medicine & Medical Imaging
Shu Wen Sun, Xun Xu, Qiu Ping Liu, Jie Neng Chen, Fei Peng Zhu, Xi Sheng Liu, Yu Dong Zhang, Jie Wang
Summary: An artificial intelligence (AI) tool called LiSNet was developed for scoring and interpreting hepatocellular carcinoma (HCC) aggressiveness using computed tomography (CT) imaging. LiSNet showed comparable results to subspecialists in assessing HCC aggressiveness and predicting histopathological microvascular invasion. When combined with experience-based binary diagnosis, LiSNet achieved the best predictive ability for microvascular invasion. Furthermore, LiSNet was able to predict overall survival after surgery.
Article
Radiology, Nuclear Medicine & Medical Imaging
Adrian Kobe, Yanick Kindler, Ernst Klotz, Gilbert Puippe, Florian Messmer, Hatem Alkadhi, Thomas Pfammatter
Summary: This study aimed to evaluate the fusion of pre-RFA MR imaging with post-treatment P-CT for predicting local tumor recurrence after RFA of HCCs. The results showed that this method is highly accurate in determining treatment success by predicting local tumor recurrence.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pei Nie, Ning Wang, Jing Pang, Guangjie Yang, Shaofeng Duan, Jingjing Chen, Wenjian Xu
Summary: This study evaluated the value of a radiomics nomogram in differentiating HCA from HCC in the noncirrhotic liver, showing that the radiomics nomogram has the potential to improve diagnostic accuracy compared to other models.
ACADEMIC RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yangling Peng, Hao Tang, Yuanying Huang, Xiaoqian Yuan, Xing Wang, Zijuan Ran, Wei Deng, Renwei Liu, Xiaosong Lan, Hesong Shen, Jiuquan Zhang
Summary: This study developed a model based on CT scans to predict preoperative liver failure in patients with resectable hepatocellular carcinoma. The model, which used extracellular volume and liver volumetry as predictors, outperformed existing scoring systems in terms of predictive performance.
INSIGHTS INTO IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jimi Huh, Bohyun Kim, Jei Hee Lee, Je Hwan Won, Jinoo Kim, Yohan Kwon, Jai Keun Kim
Summary: Adding arterial subtraction images to LI-RADS v2018 LR-TR categorization in patients treated with TACE for HCC significantly increases the sensitivity for detecting viable tumors without compromising specificity and improves diagnostic confidence.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ji Eun Lee, Seo-Youn Choi, Min Hee Lee, Sanghyeok Lim, Ji Hye Min, Jeong Ah Hwang, Sunyoung Lee, Jung Hoon Kim
Summary: The combination of clinical and imaging findings can aid in predicting malignant ampullary strictures. Jaundice, presence of ampullary mass, non-similar enhancement of the ampulla to the duodenum, and proportional dilatation of the bile duct are important factors for predicting malignant ampullary strictures.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Wenjie Miao, Pei Nie, Guangjie Yang, Yangyang Wang, Lei Yan, Yujun Zhao, Ting Yu, Mingming Yu, Fengyu Wu, Wei Rao, Zhenguang Wang
Summary: The study demonstrated that a model based on FDG PET/CT metabolic parameters could effectively predict early recurrence of hepatocellular carcinoma after liver transplantation, with higher clinical practicability compared to traditional Milan criteria and UCSF criteria.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Review
Medicine, General & Internal
Gianvito Candita, Sara Rossi, Karolina Cwiklinska, Salvatore Claudio Fanni, Dania Cioni, Riccardo Lencioni, Emanuele Neri
Summary: Hepatocellular carcinoma (HCC) is a significant cause of oncologic mortality worldwide and poses challenges for healthcare systems. Early detection and appropriate therapy are crucial for improving patient outcomes. Imaging techniques play a vital role in the surveillance, detection, diagnosis, and post-treatment follow-up of HCC. The unique imaging characteristics of HCC lesions, especially the assessment of their vascularity using contrast-enhanced CT, MR, or CEUS, allow for accurate noninvasive diagnosis and staging. The use of imaging has expanded to include the detection of early-stage hepatocarcinogenesis using ultrasound and hepatobiliary MRI contrast agents, as well as the application of artificial intelligence for diagnostic prediction, prognosis, and treatment evaluation.
Article
Radiology, Nuclear Medicine & Medical Imaging
Angele Bonnin, Carole Durot, Manel Djelouah, Anthony Dohan, Lionel Arrive, Pascal Rousset, Christine Hoeffel
Summary: The perihepatic space is commonly involved in various diseases, including intrahepatic lesions extending to the liver capsule and disease conditions from adjacent organs. The dissemination of peritoneal processes can also affect this space. MRI is valuable in assessing and diagnosing infectious, tumor-related, and other conditions in the perihepatic area compared to CT.
KOREAN JOURNAL OF RADIOLOGY
(2021)
Article
Oncology
Feifei Gao, Yi Wei, Tong Zhang, Hanyu Jiang, Qian Li, Yuan Yuan, Shan Yao, Zheng Ye, Shang Wan, Xiaocheng Wei, Lisha Nie, Hehan Tang, Bin Song
Summary: Early detection and diagnosis of HCC is crucial for prognosis. This study evaluated the detection performance of hepatic nodules using different contrast agents and compared the diagnostic performances using different criteria. The results showed that different MR protocols provided high lesion detection rate and diagnostic performance for HCC.
FRONTIERS IN ONCOLOGY
(2022)
Review
Gastroenterology & Hepatology
Christina Liava, Emmanouil Sinakos, Elissavet Papadopoulou, Lamprini Giannakopoulou, Stamatia Potsi, Anestis Moumtzouoglou, Anthi Chatziioannou, Loukas Stergioulas, Lydia Kalogeropoulou, Ioannis Dedes, Evangelos Akriviadis, Danai Chourmouzi
Summary: Hepatocellular carcinoma is a common cancer associated with various risk factors. Diagnosis and monitoring of HCC can be done through liver ultrasound, CT, and MRI. Liver biopsy is used for specific nodules that cannot be definitively diagnosed as HCC through imaging. LI-RADS is a comprehensive system that ensures standardized interpretation of liver examinations and has achieved international consensus among liver experts.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyunho Cha, Jin-Young Choi, Young Nyun Park, Kyunghwa Han, Mi Jang, Myeong-Jin Kim, Mi-Suk Park, Hyungjin Rhee
Summary: This study investigated the imaging findings of macrotrabecular-massive hepatocellular carcinoma (MTM-HCC) on CT and MRI. The results showed that MTM-HCC was associated with certain imaging characteristics on CT and MRI, such as arterial phase hypovascular component and non-smooth tumor margin. The MRI diagnostic criteria for MTM-HCC were applicable on CT, showing similar diagnostic performance and prognostic significance.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, General & Internal
Takashi Ota, Masatoshi Hori, Kosuke Sasaki, Hiromitsu Onishi, Atsushi Nakamoto, Mitsuaki Tatsumi, Hideyuki Fukui, Kazuya Ogawa, Noriyuki Tomiyama
Summary: Understanding intratumoral fat in hepatocellular carcinoma (HCC) is important for prognosis. The study found a strong correlation between fat quantification using DECT and CSI technologies in liver fat content analysis.
Article
Radiology, Nuclear Medicine & Medical Imaging
I. Molwitz, M. Leiderer, R. McDonough, R. Fischer, A-K. Ozga, C. Ozden, E. Tahir, D. Koehler, G. Adam, J. Yamamura
Summary: Quantifying fat within skeletal muscle using DECT is feasible and reliable, with excellent correlations between DECT-FF and MR-FF, DECT VNC HU and MR-FF, and DECT-FF and DECT VNC HU. DECT muscle analysis offers a new approach to determine muscle quality, crucial for diagnosing and monitoring sarcopenia as a comorbidity associated with poor clinical outcomes.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yeun-Yoon Kim, Sunyoung Lee, Jaeseung Shin, Won Jeong Son, Hyejung Shin, Ji Eun Lee, Jeong Ah Hwang, Yong Eun Chung, Jin-Young Choi, Mi-Suk Park
Summary: The study systematically compared the performance of CT/MRI LI-RADS category 5 (LR-5) for diagnosing HCC between 2017 and 2018 versions, finding no significant difference in sensitivity and specificity between the two versions. The most common underlying liver disease (hepatitis B or hepatitis C) was a significant factor contributing to the heterogeneity of sensitivities among studies for both versions.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yoshisuke Kadoya, Tosiaki Miyati, Satoshi Kobayashi, Naoki Ohno, Toshifumi Gabata
Summary: The study found that gravity reduces IVCF and AAF, resulting in decreased velocity of both. Therefore, it is important to consider the effect of gravity on IVCF and AAF when managing patients with circulatory diseases.
Article
Environmental Sciences
Xian Liang Sun, Teruhiko Kido, Hideaki Nakagawa, Muneko Nishijo, Masaru Sakurai, Masao Ishizaki, Yuko Morikawa, Rie Okamoto, Akie Ichimori, Naoki Ohno, Satoshi Kobayashi, Toshiaki Miyati, Kazuhiro Nogawa, Yasushi Suwazono
Summary: A 30-year follow-up study in a cadmium-polluted area of Japan showed fluctuations in urinary cadmium concentrations among men and women. The study revealed that urinary N-acetyl-beta-d-glucosaminidase/creatinine (U-NAG/Cr) and serum alkaline phosphatase were sensitive biomarkers for reflecting renal and bone damage caused by cadmium poisoning.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Atsushi Takamatsu, Kotaro Yoshida, Masaru Obokata, Dai Inoue, Norihide Yoneda, Yoshifumi Kadono, Satoshi Kobayashi, Toshifumi Gabata
Summary: This study found a 3% prevalence of RCC-related CSI, with the tumors pathologically diagnosed as clear cell RCC. The sensitivity, specificity, and accuracy of CSI on CT were 50%, 99.7%, and 97.1% respectively. The presence of CSI on CT did not have a significant impact on overall survival and recurrence-free survival rates of patients.
ABDOMINAL RADIOLOGY
(2021)
Article
Gastroenterology & Hepatology
Taro Yamashita, Naohiko Koshikawa, Tetsuro Shimakami, Takeshi Terashima, Masatoshi Nakagawa, Kouki Nio, Rika Horii, Noriho Iida, Kazunori Kawaguchi, Kuniaki Arai, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Azusa Kitao, Satoshi Kobayashi, Shizuko Takahara, Yasuhito Imai, Kenichi Yoshimura, Toshinori Murayama, Yasunari Nakamoto, Eisaku Yoshida, Toru Yoshimura, Motoharu Seiki, Shuichi Kaneko
Summary: The study found that the LG2m gene signature is associated with poor prognosis in hepatocellular carcinoma (HCC) patients, and elevated serum LG2m may be a risk factor for HCC development. In chronic hepatitis C (CHC) patients who have achieved sustained virological response (SVR), elevated serum LG2m is correlated with a high incidence of HCC.
Article
Radiology, Nuclear Medicine & Medical Imaging
Y. Takatsu, M. Nakamura, T. Shiozaki, S. Narukami, D. Yoshimaru, T. Miyati, S. Kobayashi
Summary: The study aimed to calculate the cut-off value of quantitative liver-portal vein contrast ratio (Q-LPC) based on tumour detectability using ROC curves for evaluation of hepatobiliary phase MRI. Results showed that Q-LPC had good sensitivity and specificity in assessing liver contrast on MRI, with the AUC-ROC value at 0.858.
CLINICAL RADIOLOGY
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Satoshi Kobayashi
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Kenichiro Okumura, Satoshi Kobayashi, Takahiro Ogi, Takumi Sugiura, Yu Zhang, Mao Kanatani, Norihide Yoneda, Azusa Kitao, Kazuto Kozaka, Toshifumi Gabata, Wataru Koda
Summary: TAE for massive APF resulted in improved hepatic reserve, disappearance of PVT, and improvement of portal hypertension; however, embolization of multiple branches may still be required in some cases.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Satoshi Kobayashi
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Naoki Ohno, Tosiaki Miyati, Fumiki Sugita, Genki Nanbu, Yuki Makino, Noam Alperin, Toshifumi Gabata, Satoshi Kobayashi
Summary: The study successfully quantified rCBF noninvasively using a novel diffusion imaging method called phase contrast (DPC). Results showed a significant positive correlation between DPC and ASL in gray matter, while the correlation in white matter was poor.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Miho Okuda, Satoshi Kobayashi, Kazu Toyooka, Rikuto Yoshimizu, Junsuke Nakase, Hiroyuki Hayashi, Yu Ueda, Toshifumi Gabata
Summary: This study quantified and differentiated the UTE-T2* values of normal knee ligaments and tendons, confirming that UTE-T2* mapping can accurately quantify the ACL, PCL, and PT in normal volunteer knee joints.
Article
Fisheries
Mariko Tawara, Tosiaki Miyati, Rika Sawada, Naoki Ohno, Riho Okamoto, Yoshino Maehara, Ryo Yagawa, Ryosuke Sakai, Hiroko Kawashima, Toshifumi Gabata, Satoshi Kobayashi
Summary: The study investigates the use of MRI for quality and composition assessments of intact yellowtail, finding that cultured yellowtail have significantly higher fat fraction compared to natural fish, with differences observed in specific regions.
AQUACULTURE RESEARCH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Naoki Ohno, Tosiaki Miyati, Hirotaka Oyabu, Toshifumi Gabata, Satoshi Kobayashi
Summary: The COMBET method allows for optimal noise image acquisition, while the DELSET method struggles to suppress long T-2 signals in certain areas. Consequently, DELSET may provide inaccurate results for long T-2 regions, while COMBET enables accurate evaluation of SNR even in these regions.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Takashi Hamaguchi, Tosiaki Miyati, Naoki Ohno, Tatsuhiko Matsushita, Tadanori Takata, Yukihiro Matsuura, Satoshi Kobayashi, Toshifumi Gabata
Summary: This study analyzed the spatial characteristics of acoustic noise in MRI and investigated the effect of a human-body phantom on the noise. The results showed that the presence of the phantom increased the peak sound pressure levels of the acoustic noise at some positions, while decreasing it at others. The peak frequencies of the acoustic noise were most commonly in the range of 2000-3000 Hz.
Article
Multidisciplinary Sciences
Takumi Sugiura, Kenichiro Okumura, Motomitsu Sasaki, Junichi Matsumoto, Takahiro Ogi, Norihide Yoneda, Azusa Kitao, Kazuto Kozaka, Wataru Koda, Satoshi Kobayashi, Toshifumi Gabata
Summary: This study aimed to identify risk factors for transient severe motion (TSM) in dynamic MRI using gadoxetate disodium and investigate the cause. The results showed that a low albumin level was an independent risk factor for TSM, and gadoxetate disodium caused significant tachypnea in rats.
Article
Radiology, Nuclear Medicine & Medical Imaging
Iyo Tanimura, Norihide Yoneda, Azusa Kitao, Kouki Nio, Shuichi Kaneko, Mitsuyoshi Okazaki, Hiroko Ikeda, Satoshi Kobayashi, Toshifumi Gabata
Summary: We report a rare case of intrahepatic cholangiocarcinoma (iCCA) that arose from a simple hepatic cyst. The diagnosis was confirmed through CT and MRI, and treated with surgery.
ABDOMINAL RADIOLOGY
(2022)