Article
Psychology, Clinical
Deepiksana Keerthy, Joht Singh Chandan, Juste Abramovaite, Krishna Margadhamane Gokhale, Siddhartha Bandyopadhyay, Ed Day, Steven Marwaha, Matthew R. Broome, Krishnarajah Nirantharakumar, Clara Humpston
Summary: This study investigates the relationship between cannabis exposure and the risks of mental illness diagnoses or treatment and finds that cannabis exposure is associated with an increased risk of developing mental health disorders.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Astronomy & Astrophysics
Chao Liu, Michael E. Jones, Angela C. Taylor
Summary: The performance of the data converters in the Xilinx ZU28DR RFSoC, particularly the ADCs, was evaluated for radio astronomy applications. The results indicate that the ADCs are sufficient for these applications and meet vendor specifications.
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY
(2021)
Article
Psychiatry
Kelly Fleetwood, Sarah H. Wild, Daniel J. Smith, Stewart W. Mercer, Kirsty Licence, Cathie L. M. Sudlow, Caroline A. Jackson
Summary: Pre-existing severe mental illness (SMI) is associated with higher mortality rates and increased risk of further stroke and vascular events among stroke patients. Immediate actions are required to understand and address the underlying reasons for these disparities.
BRITISH JOURNAL OF PSYCHIATRY
(2022)
Review
Medicine, General & Internal
Davis Kibirige, Nyasatu Chamba, Irene Andia-Biraro, Kajiru Kilonzo, Sweetness Naftal Laizer, Isaac Sekitoleko, Andrew Peter Kyazze, Sandra Ninsiima, Phillip Ssekamatte, Felix Bongomin, Lucy Elauteri Mrema, Willyhelmina Olomi, Theodora D. Mbunda, Nyanda Elias Ntinginya, Issa Sabi, Katrina Sharples, Philip Hill, Lindsey Te Brake, Josephine VandeMaat, Reinout VanCrevel, Julia Alison Critchley
Summary: There is a lack of contemporary data on the attainment of optimal diabetes treatment goals and the burden of diabetes complications in adult populations with type 2 diabetes in Africa. This study aimed to document the current status of attainment of key indicators of optimal diabetes care and the prevalence of diabetes complications in this population. The findings suggest that achieving optimal treatment goals, especially for HbA1c, remains a challenge in adult patients with type 2 diabetes in Africa. Diabetes complications, particularly diabetic peripheral neuropathy and retinopathy, are highly prevalent.
Article
Public, Environmental & Occupational Health
Xiao-Yan He, Christine Migliorini, Zhuo-Hui Huang, Fei Wang, Rui Zhou, Zi-Lang Chen, Yao-Nan Xiao, Qian-Wen Wang, Shi-Bin Wang, Carol Harvey, Cai-Lan Hou
Summary: This study examined the quality of life (QoL) of patients with schizophrenia in primary mental health care in China, and identified risk factors for QoL over time. The findings showed that the physical, environmental, and social relationships domains of QoL improved after a 2-year period, but the psychological domain did not. Factors such as earlier age of onset, older age, employment status, marital status, waist circumference, medication usage, hospitalizations, insomnia, depressive and negative symptoms, and treatment insight were independently associated with poor QoL in patients with schizophrenia.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Psychiatry
Wen-Wang Rao, Yun-Shu Zhang, Chee H. Ng, Li-Jun Cui, Jian-Feng Li, Lin Li, Gabor S. Ungvari, Ke-Qing Li, Yu-Tao Xiang
Summary: This study investigated the prevalence of schizophrenia and its association with socio-demographic factors in Hebei province, an important agricultural region in China. Unmarried status, lower education level, unemployment, lower income, and family history of psychiatric disorders were independently associated with a higher risk of schizophrenia, while age above 60 years was associated with a lower risk. The prevalence of schizophrenia in Hebei province appeared to be lower compared to other regions of China or other countries.
ASIAN JOURNAL OF PSYCHIATRY
(2021)
Article
Clinical Neurology
Boback Ziaeian, Haolin Xu, Roland A. Matsouaka, Ying Xian, Yosef Khan, Lee S. Schwamm, Eric E. Smith, Gregg C. Fonarow
Summary: We provide timely, reliable, and actionable US national surveillance data for acute ischemic stroke (AIS) using Bayesian interpolation poststratification weights, which can contribute to quality improvement in stroke care and outcomes.
Article
Psychiatry
Saleha Shafie, Ellaisha Samari, Anitha Jeyagurunathan, Edimansyah Abdin, Sherilyn Chang, Siow Ann Chong, Mythily Subramaniam
Summary: The study found no significant differences in QoL domain scores between male and female patients with schizophrenia, but revealed variations in different ethnicities, educational backgrounds, and marital statuses. This highlights the importance of considering these sociodemographic characteristics in treatments targeting QoL for patients with mental illnesses.
Article
Medicine, General & Internal
Chiamaka Chiedozie, Mark E. Murphy, Tom Fahey, Frank Moriarty
Summary: The study found that GP practices in England typically use 130 different medications in the bulk of their prescribing, with higher DU90% associated with higher levels of low-priority prescribing and prescribing costs. Increasing use of personal formularies may enhance prescribing quality and reduce costs.
Article
Public, Environmental & Occupational Health
Louise Tina Day, Qazi Sadeq-ur Rahman, Ahmed Ehsanur Rahman, Nahya Salim, K. C. Ashish, Harriet Ruysen, Tazeen Tahsina, Honorati Masanja, Omkar Basnet, Georgia R. Gore-Langton, Sojib Bin Zaman, Josephine Shabani, Anjani Kumar Jha, Vladimir Sergeevich Gordeev, Shafiqul Ameen, Donat Shamba, Bijay Jha, Dorothy Boggs, Tanvir Hossain, Kizito Shirima, Ram Chandra Bastola, Kimberly Peven, Abu Bakkar Siddique, Godfrey Mbaruku, Rajendra Paudel, Angela Baschieri, Aniqa Tasnim Hossain, Stefanie Kong, Asmita Paudel, Anisuddin Ahmed, Simon Cousens, Shams El Arifeen, Joy E. Lawn
Summary: The research assessed the validity of maternal and newborn health-care coverage indicators in five hospitals in Bangladesh, Nepal, and Tanzania, finding that exit surveys had low accuracy for specific clinical interventions, and hospital registers resulted in variable data quality due to lack of standardization.
LANCET GLOBAL HEALTH
(2021)
Article
Oncology
Essa Tawfiq, Romana Pylypchuk, J. Mark Elwood, Mark Mckeage, Sue Wells, Vanessa Selak
Summary: The study demonstrates that cancer survivors have a higher risk of cardiovascular disease, especially patients with myeloma, lung cancer, and non-Hodgkin lymphoma. Prioritizing cardiovascular disease risk management among cancer survivors is essential.
Article
Medicine, General & Internal
Jacques Donnez, Hugh S. Taylor, Elizabeth A. Stewart, Linda Bradley, Erica Marsh, David Archer, Ayman Al-Hendy, Felice Petraglia, Nelson Watts, Jean-Pierre Gotteland, Elke Bestel, Paul Terrill, Ernest Loumaye, Andrew Humberstone, Elizabeth Garner
Summary: The results of two phase 3 trials demonstrated that Linzagolix significantly reduced heavy menstrual bleeding and the partial suppression of Linzagolix (100 mg) as a monotherapy provides a unique treatment option for women with symptomatic uterine fibroids who are unable or unwilling to take hormonal add-back therapy.
Review
Biochemistry & Molecular Biology
Abdul-Rizaq Hamoud, Karen Bach, Ojal Kakrecha, Nicholas Henkel, Xiaojun Wu, Robert E. McCullumsmith, Sinead M. O'Donovan
Summary: For over a century, the relationship between schizophrenia diagnosis and cancer development has been complex. Epidemiological studies have shown mixed findings in terms of the incidence of cancer in schizophrenia patients. The hypothesized reduction in cancer incidence rates in this patient population may be attributed to pathophysiological changes associated with the disease. The adenosine system is believed to play a role in the neurobiology of schizophrenia and in the tumor microenvironment in cancer. Examining the adenosine system in schizophrenia patients is important for gaining insight into these complex disorders.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Medicine, General & Internal
Lara Brauer, Max Geraedts
Summary: This study aims to investigate the utilization and quality of care, the influence of structural determinants on quality, and the patient's experiences on endometriosis healthcare in rural Hesse. A mixed methods approach will be used to accurately assess the care situation for endometriosis patients in seven counties. This study will provide valuable insights into the treatment and experiences of endometriosis patients in rural areas.
Article
Multidisciplinary Sciences
Zsofia Csajbok, Anna Kagstrom, Pavla Cermakova
Summary: The study found that season of birth and month of birth are not reliable predictors of anxiety and depression, regardless of gender, region, or overall.
SCIENTIFIC REPORTS
(2022)
Article
Clinical Neurology
Raed A. Joundi, Scott B. Patten, Jeanne V. A. Williams, Eric E. Smith
Summary: Excess sleep, especially in individuals under 70 years old, may increase the risk of stroke. This study supports the current recommendation of 7-9 hours of sleep per night. Further research is needed to better understand the relationship between sleep and cerebrovascular disease.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
(2023)
Review
Psychology, Clinical
Daniel J. Devoe, Angela Han, Alida Anderson, Debra K. Katzman, Scott B. Patten, Andrea Soumbasis, Jordyn Flanagan, Georgios Paslakis, Ellie Vyver, Gisele Marcoux, Gina Dimitropoulos
Summary: The COVID-19 pandemic has had a negative impact on individuals with eating disorders, leading to worsening symptoms, increased anxiety and depression, and changes in body mass index (BMI). This systematic review provides important insights into the effects of COVID-19 on the physical and mental health of individuals with eating disorders.
INTERNATIONAL JOURNAL OF EATING DISORDERS
(2023)
Article
Geriatrics & Gerontology
Sophie Hu, Scott Patten, Anna Charlton, Karyn Fischer, Gordon Fick, Eric E. Smith, Zahinoor Ismail
Summary: This study compared the utility of MBI-C and NPI-Q in capturing non-cognitive symptoms in patients with subjective cognitive decline, mild cognitive impairment, and dementia. The results showed that both MBI-C and NPI-Q were effective in characterizing these symptoms, and MBI-C was able to capture non-cognitive symptoms across different cognitive stages.
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
(2023)
Article
Psychiatry
Asmita Bhattarai, Nathan King, Kamala Adhikari, Gina Dimitropoulos, Dan Devoe, Jin Byun, Melanie Li, Daniel Rivera, Simone Cunningham, Andrew G. M. Bulloch, Scott B. Patten, Anne Duffy
Summary: Childhood adversities and parental divorce are associated with mental health concerns among university students. Childhood adversities may impact later mental health through an association with stress sensitivity, self-esteem, and sleep problems.
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
(2023)
Article
Health Care Sciences & Services
Brooke Allemang, Susan Samuel, Karina Pintson, Megan Patton, Katelyn Greer, Marcela Farias, Keighley Schofield, Kathleen C. C. Sitter, Scott B. B. Patten, Andrew S. S. Mackie, Gina Dimitropoulos
Summary: This study examines the perspectives of transition-age youth with co-occurring chronic health and mental health conditions as they prepare to exit pediatric health and mental health services. The findings reveal the interconnectedness of physical and mental health, the impact of mental health on transition readiness and self-management, and recommendations for service provision.
BMC HEALTH SERVICES RESEARCH
(2023)
Article
Clinical Neurology
Raed A. Joundi, Megan E. O'Connell, Scott Patten, Eric E. Smith
Summary: The relation between cognitive and functional decline after stroke is not well studied. This study used a comprehensive cohort to investigate the association between stroke, cognitive decline, and functional decline. The results showed that cognitive decline mediated the relationship between prior stroke and functional decline.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
(2023)
Article
Rehabilitation
Amanda Wurz, Delaney Duchek, Kelsey Ellis, Mannat Bansal, Marie-Eve Carrier, Lydia Tao, Laura Dyas, Linda Kwakkenbos, Brooke Levis, Ghassan El-Baalbaki, Danielle B. Rice, Yin Wu, Richard S. Henry, Laura Bustamante, Sami Harb, Shannon Hebblethwaite, Scott B. Patten, Susan J. Bartlett, John Varga, Luc Mouthon, Sarah Markham, Brett D. Thombs, S. Nicole Culos-Reed
Summary: This study explored the impact of the videoconference-based supportive care program (SPIN-CHAT program) on individuals with systemic sclerosis (SSc) during early COVID-19. Interviews with trial participants and research team members revealed that the program had positive effects on psychological health, provided SSc-specific support, created a safe space for group interaction, reduced boredom, and offered self-management skills.
DISABILITY AND REHABILITATION
(2023)
Review
Psychology, Clinical
Yin Wu, Brooke Levis, Federico M. Daray, John P. A. Ioannidis, Scott B. Patten, Pim Cuijpers, Roy C. Ziegelstein, Simon Gilbody, Felix H. Fischer, Suiqiong Fan, Ying Sun, Chen He, Ankur Krishnan, Dipika Neupane, Parash Mani Bhandari, Zelalem Negeri, Kira E. Riehm, Danielle B. Rice, Marleine Azar, Xin Wei Yan, Mahrukh Imran, Matthew J. Chiovitti, Jill T. Boruff, Dean McMillan, Lorie A. Kloda, Sarah Markham, Melissa Henry, Zahinoor Ismail, Carmen G. Loiselle, Nicholas D. Mitchell, Samir Al-Adawi, Kevin R. Beck, Anna Beraldi, Charles N. Bernstein, Birgitte Boye, Natalie Buel-Drabe, Adomas Bunevicius, Ceyhun Can, Gregory Carter, Chih-Ken Chen, Gary Cheung, Kerrie Clover, Ronan M. Conroy, Gema Costa-Requena, Daniel Cukor, Eli Dabscheck, Jennifer De Souza, Marina Downing, Anthony Feinstein, Panagiotis P. Ferentinos, Alastair J. Flint, Pamela Gallagher, Milena Gandy, Luigi Grassi, Martin Haerter, Asuncion Hernando, Melinda L. Jackson, Josef Jenewein, Nathalie Jette, Miguel Juliao, Marie Kjaergaard, Sebastian Kohler, Hans-Helmut Konig, Lalit K. R. Krishna, Yu Lee, Margrit Loebner, Wim L. Loosman, Anthony W. Love, Bernd Loewe, Ulrik F. Malt, Ruth Ann Marrie, Loreto Massardo, Yutaka Matsuoka, Anja Mehnert, Ioannis Michopoulos, Laurent Misery, Christian J. Nelson, Chong Guan Ng, Meaghan L. O'Donnell, Suzanne J. O'Rourke, Ahmet Ozturk, Alexander Pabst, Julie A. Pasco, Jurate Peceliuniene, Luis Pintor, Jennie L. Ponsford, Federico Pulido, Terence J. Quinn, Silje E. Reme, Katrin Reuter, Steffi G. Riedel-Heller, Alasdair G. Rooney, Roberto Sanchez-Gonzalez, Rebecca M. Saracino, Melanie P. J. Schellekens, Martin Scherer, Marcelo L. Schwarzbold, Vesile Senturk Cankorur, Louise Sharpe, Michael Sharpe, Sebastien Simard, Susanne Singer, Lesley Stafford, Jon Stone, Natalie A. Strobe, Serge Sultan, Antonio L. Teixeira, Istvan Tiringer, Alyna Turner, Jane Walker, Mark Walterfang, Liang-Jen Wang, Siegfried B. Weyerer, Jennifer White, Birgitt Wiese, Lana J. Williams, Lai-Yi Wong, Andrea Benedetti, Brett D. Thombsi
Summary: This study compared the screening accuracy of HADS-D and HADS-T for major depression and found no significant difference in diagnostic accuracy between the two. The shorter HADS-D would be preferred in most clinical and research settings as it not only reduces patient burden but also has equivalent diagnostic accuracy to HADS-T.
PSYCHOLOGICAL ASSESSMENT
(2023)
Article
Social Issues
Lisa K. Mundy, Louise Canterford, S. Ghazaleh Dashti, Hanafi Mohamad Husin, Ruth Beatson, Ben Edwards, George C. Patton
Summary: There is growing evidence that the COVID-19 pandemic has had significant negative effects on the mental health of adolescents. A study in Australia found that over 50% of participants reported depressive symptoms, and one-quarter reported anxiety symptoms during the pandemic. Adolescents with a history of mental health problems, school disengagement, and frequent peer victimization were at higher risk of experiencing mental health issues during the pandemic. Therefore, it is crucial for schools to prioritize the mental health and well-being of students, particularly during times of social disruption like the COVID-19 pandemic.
AUSTRALIAN JOURNAL OF SOCIAL ISSUES
(2023)
Article
Clinical Neurology
Elisabet Rodriguez Llorian, Wei Zhang, Amir Khakban, Kristina Michaux, Scott Patten, Anthony Traboulsee, Jiwon Oh, Shannon Kolind, Alexandre Prat, Roger Tam, Larry D. Lynd
Summary: This study examines the impact of multiple sclerosis (MS) on productivity loss and employment status. Using baseline data from the Canadian Prospective Cohort Study to Understand Progression in Multiple Sclerosis (CanProCo), the study measures MS-related productivity loss and investigates associated factors. The findings show that both employed and unemployed individuals with MS experience significant productivity loss, and modifiable factors such as disease-modifying therapies, fatigue, and cognitive processing speed impact productivity loss and employment status. Targeting these factors is likely to improve work productivity and permanence of MS patients in the workforce.
MULTIPLE SCLEROSIS JOURNAL
(2023)
Article
Multidisciplinary Sciences
Asmita Bhattarai, Gina Dimitropoulos, Andrew G. M. Bulloch, Suzanne C. Tough, Scott B. Patten
Summary: This study examined the association between specific childhood adversities and rate of all-cause hospitalization in adulthood, and found that childhood adversities significantly increased hospitalization rate in young and middle adulthood. It also identified adulthood socioeconomic and health-related factors as potential mediators of this association.
Article
Medical Informatics
Michelle Lu, Rachel E. Crooks, Diana F. Pricop, Emily Cox, Beatrice Anghelescu, Mark Hamilton, Davide Martino, Veronica Bruno, Colin B. Josephson, Scott Patten, Eric E. Smith, Pamela Roach
Summary: This study aimed to explore barriers and facilitators of virtual care from the perspective of neurological and psychiatric patients. One-on-one interviews were conducted remotely using telephone and online video teleconferencing, with a total of 57 participants. The study found that virtual care can increase accessibility and efficiency for patients and providers, indicating its potential for ongoing use in the delivery of clinical care. Patients perceived virtual care as an acceptable mode of healthcare delivery, but there remains a continued need for relationship-building between care providers and patients.
HEALTH AND TECHNOLOGY
(2023)
Article
Clinical Neurology
Dhruv Jain, Charles N. Bernstein, Lesley A. Graff, Scott B. Patten, James M. Bolton, John D. Fisk, Carol Hitchon, James J. Marriott, Ruth Ann Marrie
Summary: This study compared the prevalence of pain and the association between pain and pain interference, as well as social participation, in different subtypes of multiple sclerosis. The results showed that pain was common among all participants, with no differences between subtypes. However, individuals with progressive multiple sclerosis reported higher pain interference and lower social participation compared to those with relapsing-remitting multiple sclerosis.
MULTIPLE SCLEROSIS JOURNAL-EXPERIMENTAL TRANSLATIONAL AND CLINICAL
(2023)
Meeting Abstract
Neurosciences
Marilena DeMayo, Jaeden Cole, Maya Sohn, Signe Bray, Ashley Harris, Scott B. Patten, Alexander McGirr
BIOLOGICAL PSYCHIATRY
(2023)
Article
Health Care Sciences & Services
Andrew J. Stewart, Scott B. Patten, Kirsten M. Fiest, Tyler S. Williamson, James P. Wick, Paul E. Ronksley
Summary: Schizophrenia patients have diverse healthcare needs, but little research has been done to understand the heterogeneity among them. This study used a data-driven approach to identify subgroups of high-cost schizophrenia patients, which can inform interventions and resource allocation. The findings provide insights into different patient groups and their clinical profiles, facilitating policy-making and cost reduction.
HEALTH SERVICES INSIGHTS
(2023)
