Article
Oncology
Daniel R. Richardson, P. Christopher Parish, Xianming Tan, Julia Fabricio, Cami L. Andreini, Charles H. Hicks, Brian C. Jensen, Benyam Muluneh, Joshua F. Zeidner
Summary: The use of the Bazett formula for QTc correction in cancer patients receiving chemotherapy may lead to higher QTc values and an increased risk of grade 3 CTCAE toxic effects. This study suggests that the selection of a standardized QTc formula, such as Fridericia or Framingham, is important to ensure accurate monitoring and appropriate clinical management.
Article
Multidisciplinary Sciences
Chanki Park, Inchan Youn, Sungmin Han
Summary: In this study, a single-lead ECG-based heart rate variability analysis algorithm was proposed to quantify autonomic nervous system activity during meditation. The results showed significant increases and decreases in vagal and sympathetic tones during meditation, consistent with self-reports and experimental protocols.
SCIENTIFIC REPORTS
(2022)
Article
Peripheral Vascular Disease
Thomas Weber, Athanase D. Protogerou, Mohsen Agharazii, Antonis Argyris, Sola Aoun Bahous, Jose R. Banegas, Ronald K. Binder, Jacques Blacher, Andrea Araujo Brandao, Juan J. Cruz, Kathrin Danninger, Cristina Giannatasio, Auxiliadora Graciani, Bernhard Hametner, Piotr Jankowski, Yan Li, Alessandro Maloberti, Christopher C. Mayer, Barry J. McDonnell, Carmel M. McEniery, Marco Antonio Mota Gomes, Annelise Machado Gomes, Maria Lorenza Muiesan, Janos Nemcsik, Anna Paini, Enrique Rodilla, Aletta E. Schutte, Petros P. Sfikakis, Dimitrios Terentes-Printzios, Alexandre Vallee, Charalambos Vlachopoulos, Lisa Ware, Ian Wilkinson, Robert Zweiker, James E. Sharman, Siegfried Wassertheurer
Summary: Central systolic blood pressure (cSBP) is more closely associated with hypertension-mediated organ damage and prognosis than brachial systolic blood pressure. This study investigated the 24-hour profiles of brachial and central SBP in untreated adults, providing reference values and analyzing daytime-nighttime variability. The findings have potential implications for refining hypertension diagnosis and management.
Article
Rheumatology
Sine Sondergaard Korsholm, Daniel C. Andersson, John Bonde Knudsen, Maryam Dastmalchi, Axel C. P. Diederichsen, Oke Gerke, Nanna Witting, Soren Jacobsen, Redi Pecini, Tina Friis, Markus E. Krogager, Ingrid E. Lundberg, Louise Diederichsen
Summary: The aim of this study was to investigate cardiac involvement detected by ECG in patients with idiopathic inflammatory myopathies (IIMs) and evaluate the association between the autoantibody profile and ECG changes in these patients. The results showed that patients with IIM had increased QTc duration and anti-Mi2, anti-Pl-7, and elevated CRP levels were associated with QTc abnormalities.
Article
Multidisciplinary Sciences
Andy Schumann, Karl-Juergen Baer
Summary: This study provides a database of high-resolution biological signals to describe the effect of healthy aging on cardiovascular regulation, demonstrating the decline of heart rate variability with increasing age.
Review
Medicine, General & Internal
Jose Casana, Clovis Varangot-Reille, Joaquin Calatayud, Luis Suso-Marti, Enrique Sanchis-Sanchez, Ramon Aiguade, Ruben Lopez-Bueno, Pedro Gargallo, Ferran Cuenca-Martinez, Maria Blanco-Diaz
Summary: A systematic search and meta-analysis found that high-intensity interval training (HIIT) has almost no significant effects on biological and body composition variables in patients with musculoskeletal disorders (MSKD), except for resting heart rate.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Peripheral Vascular Disease
Han-Kyul Kim, Rie Ishizawa, Ayumi Fukazawa, Zhongyun Wang, Ursa Bezan Petric, Ming Chang Hu, Scott A. Smith, Masaki Mizuno, Wanpen Vongpatanasin
Summary: This study found that SGLT2i can reduce blood pressure in hypertensive patients and attenuate renal sympathetic nerve activity and skeletal muscle reflex activity. Additionally, the study found that SGLT2i has no impact on glycemic control. These findings have important clinical implications for preventing hypertension and hypertensive heart disease in young prehypertensive individuals.
Article
Medicine, General & Internal
Piotr Sobieraj, Maciej Sinski, Jacek Lewandowski
Summary: The study found that elevated resting heart rate remains an important independent cardiovascular risk factor that is unrelated to the reduction of systolic blood pressure.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Christine Sailer, Hannah Edelmann, Cullen Buchanan, Pedro Giro, Matthew Babcock, Christine Swanson, Melanie Spotts, Margaret Schulte, Ashley Pratt-Cordova, Greg Coe, Mark Beindorff, Robert L. Page, Amrut Ambardekar, Jay D. Pal, Wendy Kohrt, Eugene Wolfel, Justin S. Lawley, Takashi Tarumi, William K. Cornwell
Summary: CF-LVAD implantation in patients with advanced heart failure results in modest improvements in autonomic tone, but persistent reductions in cardiac baroreceptor sensitivity. Exercise-induced increases in blood pressure are blunted post-LVAD implantation.
CIRCULATION-HEART FAILURE
(2021)
Article
Peripheral Vascular Disease
Massimo Nardone, Catherine F. Notarius, Mark B. Badrov, Philip J. Millar, John S. Floras
Summary: This study compared the transduction of sympathetic firing into blood pressure in treated patients with heart failure with reduced ejection fraction (HFrEF) and healthy controls. The results showed that treated HFrEF patients had lower sympathetic-BP transduction, even when muscle sympathetic nerve activity (MSNA) was not elevated, and this transduction diminished further with disease progression.
Article
Cardiac & Cardiovascular Systems
Gyu Chul Oh, Seokyung An, Hae-Young Lee, Hyun-Jai Cho, Eun-Seok Jeon, Sang Eun Lee, Jae-Joong Kim, Seok-Min Kang, Kyung-Kuk Hwang, Myeong-Chan Cho, Shung Chull Chae, Dong-Ju Choi, Byung-Su Yoo, Kye Hun Kim, Sue K. Park, Sang Hong Baek
Summary: In patients hospitalized for heart failure with reduced ejection fraction (HFrEF), changes in blood pressure and heart rate were assessed, and a modified reverse shock index (mRSI) was found to be a significant predictor of early outcomes. The mRSI could be used as a tool to assess patient status and guide physicians in treating patients with HFrEF.
Article
Environmental Sciences
Gabriela de Oliveira Teles, Paulo Gentil, Lucas Raphael Bento e Silva, Watila de Moura Sousa, Camila Simoes Seguro, Ana Cristina Silva Rebelo
Summary: This study compared the acute effects of different high-intensity interval exercise (HIIE) protocols and moderate-intensity continuous exercise (MICE) on blood glucose, blood pressure, and heart rate in people with Type 2 Diabetes Mellitus. The study found that HIIE had more significant reductions in blood glucose and blood pressure compared to MICE.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Peripheral Vascular Disease
Philippe Gosse, Antoine Cremer, Ajay J. Kirtane, Melvin D. Lobo, Manish Saxena, Joost Daemen, Yale Wang, Johannes Stegbauer, Michael A. Weber, Josephine Abraham, Kazuomi Kario, Sripal Bangalore, Lisa Claude, Yuyin Liu, Michel Azizi
Summary: The study found that baseline nighttime systolic blood pressure and its variability can predict the blood pressure response to renal denervation in patients with hypertension, which is helpful in identifying potential responders.
Article
Endocrinology & Metabolism
Delia Almeida Gonzalez, Maria del Cristo Rodriguez-Perez, Manuel Fuentes Ferrer, Francisco Javier Cuevas Fernandez, Itahisa Mercelino Rodriguez, Antonio Cebrera de Leon
Summary: This study aimed to evaluate the cardiovascular protective role of irisin in the general population. A cross-sectional analysis was conducted on a large sample, and the results showed that irisin was associated with factors such as heart rate, blood pressure, body mass index, and lifestyle. These findings suggest that irisin plays a protective role in maintaining cardiometabolic health.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Avneet Oberoi, Caroline Giezenaar, Kylie Lange, Karen L. Jones, Michael Horowitz, Ian Chapman, Stijn Soenen
Summary: This study found that even with relatively low intake of whey protein, there is a risk of blood pressure decrease in older men.
Review
Clinical Neurology
Jee Su Suh, Maiko Abel Schneider, Luciano Minuzzi, Glenda M. MacQueen, Stephen C. Strother, Sidney H. Kennedy, Benicio N. Frey
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2019)
Article
Clinical Neurology
Elsa Arrua-Duarte, Marta Migoya-Borja, Maria L. Barrigon, Igor Barahona, David Delgado-Gomez, Philippe Courtet, Fuensanta Aroca, Sakina J. Rizvi, Sidney H. Kennedy, Lena C. Quilty, Enrique Baca-Garcia
JOURNAL OF AFFECTIVE DISORDERS
(2019)
Article
Psychiatry
Ana C. Andreazza, Isabelle Laksono, Brisa S. Fernandes, Catherine Toben, Piotr Lewczuk, Peter Riederer, Sidney H. Kennedy, Dimitrios Kapogiannis, Florence Thibaut, Manfred Gerlach, Carla Gallo, Yong-Ku Kim, Edna Grunblatt, Lakshmi Yatham, Michael Berk, Bernhard T. Baune
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
(2019)
Editorial Material
Psychiatry
Shane J. McInerney, Armaan Fallahi, Nicole E. Edgar, Amanda K. Ceniti, Sakina J. Rizvi, Michaela Beder, Yvonne Bergmans, Sidney H. Kennedy
GENERAL HOSPITAL PSYCHIATRY
(2020)
Article
Psychiatry
Lynn Boschloo, Ella Bekhuis, Erica S. Weitz, Mirjam Reijnders, Robert J. DeRubeis, Sona Dimidjian, David L. Dunner, Boadie W. Dunlop, Ulrich Hegerl, Steven D. Hollon, Robin B. Jarrett, Sidney H. Kennedy, Jeanne Miranda, David C. Mohr, Anne D. Simons, Gordon Parker, Frank Petrak, Stephan Herpertz, Lena C. Quilty, A. John Rush, Zindel V. Segal, Jeffrey R. Vittengl, Robert A. Schoevers, Pim Cuijpers
Article
Psychiatry
Sylvia Romanowska, Glenda MacQueen, Benjamin I. Goldstein, JianLi Wang, Sidney H. Kennedy, Signe Bray, Catherine Lebel, Jean Addington
EARLY INTERVENTION IN PSYCHIATRY
(2020)
Article
Neurosciences
Nikita Nogovitsyn, Roberto Souza, Meghan Muller, Amelia Srajer, Stefanie Hassel, Stephen R. Arnott, Andrew D. Davis, Geoffrey B. Hall, Jacqueline K. Harris, Mojdeh Zamyadi, Paul D. Metzak, Zahinoor Ismail, Signe L. Bray, Catherine Lebel, Jean M. Addington, Roumen Milev, Kate L. Harkness, Benicio N. Frey, Raymond W. Lam, Stephen C. Strother, Benjamin I. Goldstein, Susan Rotzinger, Sidney H. Kennedy, Glenda M. MacQueen
Review
Behavioral Sciences
Elisa Brietzke, Emily R. Hawken, Maia Idzikowski, Janice Pong, Sidney H. Kennedy, Claudio N. Soares
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2019)
Article
Psychology, Clinical
Trisha Chakrabarty, Kate L. Harkness, Shane J. McInerney, Lena C. Quilty, Roumen V. Milev, Sidney H. Kennedy, Benicio N. Frey, Glenda M. MacQueen, Daniel J. Muller, Susan Rotzinger, Rudolf Uher, Raymond W. Lam
PSYCHOLOGICAL MEDICINE
(2020)
Article
Psychiatry
Olga Santesteban-Echarri, Glenda MacQueen, Benjamin I. Goldstein, JianLi Wang, Sidney H. Kennedy, Signe Bray, Catherine Lebel, Jean Addington
Summary: The study found that symptomatic participants scored higher in neuroticism, lower in extraversion, and lower in conscientiousness compared to non-symptomatic participants. These personality profiles were similar to those of known disorders, and early identification of this profile could aid in identifying those at risk of developing SMI.
EARLY INTERVENTION IN PSYCHIATRY
(2021)
Review
Psychiatry
Seetal Dodd, Michael Bauer, Andre F. Carvalho, Harris Eyre, Maurizio Fava, Siegfried Kasper, Sidney H. Kennedy, Jon-Paul Khoo, Carlos Lopez Jaramillo, Gin S. Malhi, Roger S. McIntyre, Philip B. Mitchell, Angela Marianne Paredes Castro, Aswin Ratheesh, Emanuel Severus, Trisha Suppes, Madhukar H. Trivedi, Michael E. Thase, Lakshmi N. Yatham, Allan H. Young, Michael Berk
Summary: Major depressive disorder is a common, recurrent, and costly disorder, with a sizeable percentage of patients failing to achieve remission with antidepressant treatment. Personalised treatment plans may be more effective for difficult to treat depression, as these patients often have complex contributing factors.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
(2021)
Review
Psychiatry
Pedro L. Ballester, Maria T. Romano, Taiane de Azevedo Cardoso, Stefanie Hassel, Stephen C. Strother, Sidney H. Kennedy, Benicio N. Frey
Summary: The study conducted a systematic review and meta-analysis to evaluate accelerated brain aging in individuals with mood or psychotic disorders. The results showed that individuals with these disorders may undergo a process of accelerated brain aging, with older individuals showing a more pronounced brain age gap, indicating a possible cumulative biological effect of illness burden.
ACTA PSYCHIATRICA SCANDINAVICA
(2022)
Article
Psychiatry
Cherise R. Chin Fatt, Sarah Asbury, Manish K. Jha, Abu Minhajuddin, Sangita Sethuram, Taryn Mayes, Sidney H. Kennedy, Jane A. Foster, Madhukar H. Trivedi
Summary: Alterations in the gut microbiome have been studied in relation to mental illnesses. By analyzing gut microbiota in a sample of depressed individuals, this study identified a co-occurrence network of bacteria that was significantly associated with clinical anxiety, suggesting a potential role of deficits in butyrate production.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Psychiatry
Sara Jalali, Lu Liu, Jianli Wang, Sidney H. Kennedy, Glenda MacQueen, Catherine Lebel, Benjamin l. Goldstein, Signe Bray, Jean Addington
Summary: This study aimed to determine early factors that may be related to the development of serious mental illnesses in at-risk youth. The results showed that female sex, attenuated psychotic symptoms, and psychological distress were significantly associated with the later transition to mental illness. These findings provide further insight into specific clinical measures for early detection of mental illnesses.
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
(2023)
Article
Psychology, Clinical
Morgan Vallati, Simone Cunningham, Raegan Mazurka, Jeremy G. Stewart, Cherie Larocque, Roumen Milev, R. Michael Bagby, Sidney H. Kennedy, Kate L. Harkness
JOURNAL OF ABNORMAL PSYCHOLOGY
(2020)
Article
Clinical Neurology
Hannah Meijs, Helena Voetterl, Alexander T. Sack, Hanneke van Dijk, Bieke De Wilde, Jan Van Hecke, Peter Niemegeers, Evian Gordon, Jurjen J. Luykx, Martijn Arns
Summary: This study used a polygenic score (PGS) and electroencephalography (EEG) data analysis to identify potential predictors for treatment outcomes in major depressive disorder (MDD). The results suggest the existence of a stable EEG network related to antidepressant-response that has potential as a predictor for MDD treatment, particularly in the case of venlafaxine.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2024)