期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 137, 期 13, 页码 4316-4319出版社
AMER CHEMICAL SOC
DOI: 10.1021/jacs.5b01138
关键词
-
资金
- NSFC [21172253, 21372256]
The first phosphine-catalyzed highly enantioselective [3 + 3] cycloaddition of Morita-Baylis-Hillman carbonates with C,N-cyclic azomethine imines is described. Using a spirocyclic chiral phosphine as the catalyst, a novel class of pharmaceutically interesting 4,6,7,11b-tetrahydro-1H-pyridazino[6,1-a]iso-quinoline derivatives were obtained in high yields with good to excellent diastereoselectivities and extremely excellent enantioselectivities (98>99% ee).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据