Review
Critical Care Medicine
Gael Dournes, Laura L. Walkup, Ilyes Benlala, Matthew M. Willmering, Julie Macey, Stephanie Bui, Francois Laurent, Jason C. Woods
Summary: Recent technological breakthroughs and novel treatments have positioned lung MRI as a valuable, radiation-free tool for clinically assessing CF. With high-resolution imaging and the ability to differentiate between inflammation and scarring tissue, MRI can provide early guidance for treatment. Additionally, MRI can evaluate regional small-airway disease and offer automated quantification methods for more objective and reproducible assessment of disease severity.
Article
Dentistry, Oral Surgery & Medicine
Dorina Willenbrock, Rainer Lutz, Wolfgang Wuest, Rafael Heiss, Michael Uder, Tessa Behrends, Matthias Wurm, Marco Kesting, Marco Wiesmueller
Summary: The aim of this study was to assess the inter- and intrarater reliability of a recently proposed scoring system for temporomandibular disorders (TMD) based on MRI findings. The results showed no significant differences between observers in the scores for the articular disk and the direction of disk luxation. However, significant differences were found in the assessment of osseous joint alterations. The DLJ scoring system based on MRI findings is feasible for routine clinical TMD assessment and may help to simplify interdisciplinary communication between radiologists and clinicians.
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
(2022)
Article
Critical Care Medicine
Mirjam Stahl, Eva Steinke, Simon Y. Graeber, Cornelia Joachim, Christoph Seitz, Hans-Ulrich Kauczor, Monika Eichinger, Susanne Haemmerling, Olaf Sommerburg, Mark O. Wielpuetz, Marcus A. Mall
Summary: The study showed that MRI can detect the progression of lung disease and the benefits of early diagnosis using NBS in preschool children with CF. Increase in MRI global score was associated with symptoms like cough and pulmonary exacerbations. MRI is suggested as a sensitive outcome measure for diagnostic monitoring and early intervention trials in preschool children with CF.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Medicine, General & Internal
Eva Steinke, Olaf Sommerburg, Simon Y. Graeber, Cornelia Joachim, Christiane Labitzke, Gyde Nissen, Isabell Ricklefs, Isa Rudolf, Matthias V. Kopp, Anna-Maria Dittrich, Marcus A. Mall, Mirjam Stahl
Summary: This study is a prospective, longitudinal cohort study aimed at determining influencing factors of early cystic fibrosis (CF) lung disease through the combined analysis of clinical information and biomaterials. The primary endpoints are the lung clearance index and magnetic resonance imaging scores, while secondary endpoints include pulmonary exacerbations, infection with pro-inflammatory pathogens, and anthropometric data.
FRONTIERS IN MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Filip Klimes, Andreas Voskrebenzev, Marcel Gutberlet, Milan Speth, Robert Grimm, Martha Dohna, Gesine Hansen, Frank Wacker, Diane Miriam Renz, Anna-Maria Dittrich, Jens Vogel-Claussen
Summary: This study aimed to investigate the efficacy of 3D phase-resolved functional lung (PREFUL)-MRI parameters in measuring the response to elexacaftor/tezacaftor/ivacaftor (ETI) therapy and their association with clinical outcomes in cystic fibrosis (CF) patients. The results showed significant improvements in all 3D PREFUL ventilation markers after ETI therapy, except for the mean RVent parameter. The improvement in ventilation volume normalized to body surface area (IVV) was significantly correlated with the relative treatment changes in MEF25 and mucus plugging score.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yiqi Hu, Qilan Hu, Chenao Zhan, Ting Yin, Tao Ai
Summary: This study investigated the intraobserver and interobserver reproducibility of diffusion-weighted imaging (DWI) measurements, diffusion-kurtosis imaging (DKI) parameters, and image quality evaluation in breast lesions between single-shot echo-planar imaging (ss-EPI) and readout-segmented echo-planar imaging (rs-EPI). The results showed that compared to ss-EPI, rs-EPI had higher intraobserver and interobserver reproducibility for quantitative diffusion-related parameters and image quality assessments.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Mohammad Danish Mangi, Steven Zadow, Wanyin Lim
Summary: Cystic lesions of the humeral head are commonly encountered on shoulder MRI, with differential diagnoses including degenerative lesions, infectious lesions, and postoperative cysts. The location, morphology, and signal characteristics of the cysts can help make a specific diagnosis. Understanding the underlying cause of the cysts is important for management.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Physiology
Kai Foerster, Hanna Marchi, Sophia Stoecklen, Olaf Dietrich, Harald Ehrhardt, Mark O. Welipultz, Andreas W. Flemmer, Benjamin Schubert, A. Marcus Mall, Birgit Ertl-Wagner, Anne Hillgendroff
Summary: This study developed a novel scoring system using MRI to assess lung structural changes in neonatal chronic lung disease. It showed high reproducibility and disease specificity, and has the potential to be used as a quantifiable endpoint in clinical trials and disease monitoring.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Vito Chianca, Domenico Albano, Stefania Rizzo, Mario Maas, Luca Maria Sconfienza, Filippo Del Grande
Summary: This study evaluated the inter-observer and inter-vendor reliability of diffusion tensor imaging parameters in the musculoskeletal system. The results showed high levels of agreement between observers and no significant inter-vendor differences were observed. This indicates that diffusion tensor imaging is highly reproducible and reliable in the musculoskeletal system.
INSIGHTS INTO IMAGING
(2023)
Review
Medicine, General & Internal
Elit Quingalahua, Mahmoud M. Al-Hawary, Jorge D. Machicado
Summary: Pancreatic cystic lesions (PCLs) are commonly found incidental findings on cross-sectional imaging. Magnetic resonance imaging (MRI) has become the preferred non-invasive method for predicting cyst type, stratifying risk of neoplasia, and monitoring changes in PCLs. In some cases, additional diagnostic approaches such as endoscopic ultrasound (EUS) and molecular analysis may be necessary for treatment decisions. The use of radiomics and artificial intelligence in MRI could enhance the stratification of PCLs and improve treatment guidance.
Article
Critical Care Medicine
Simon Y. Graeber, Diane M. Renz, Mirjam Stahl, Sophia T. Pallenberg, Olaf Sommerburg, Lutz Naehrlich, Julian Berges, Martha Dohna, Felix C. Ringshausen, Felix Doellinger, Constanze Vitzthum, Jobst Roehmel, Christine Allomba, Susanne Haemmerling, Sandra Barth, Claudia Rueckes-Nilges, Mark O. Wielpuetz, Gesine Hansen, Jens Vogel-Claussen, Burkhard Tuemmler, Marcus A. Mall, Anna-Maria Dittrich
Summary: ELX/TEZ/IVA improves CFTR function in patients with cystic fibrosis, leading to improved lung ventilation and morphology.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Biochemical Research Methods
Barbara Schmieg, Sarah Gretzinger, Sebastian Schuhmann, Gisela Guthausen, Juergen Hubbuch
Summary: Bioprinting is becoming increasingly important in tissue engineering, pharmaceutical research, and cell therapy. Magnetic resonance imaging (MRI) is an effective method for characterizing different soft materials. In this study, an MRI measurement and image analysis protocol was used to evaluate the reproducibility of different hydrogels. The results show that this method can be used to systematically investigate complex 3D objects and serve as a process control tool.
BIOTECHNOLOGY JOURNAL
(2022)
Article
Pharmacology & Pharmacy
Lena Wucherpfennig, Felix Wuennemann, Monika Eichinger, Angelika Seitz, Ingo Baumann, Mirjam Stahl, Simon Y. Graeber, Shengkai Zhao, Jaehi Chung, Jens-Peter Schenk, Abdulsattar Alrajab, Hans-Ulrich Kauczor, Marcus A. Mall, Olaf Sommerburg, Mark O. Wielpuetz
Summary: Chronic rhinosinusitis (CRS) in cystic fibrosis (CF) can cause nasal congestion, rhinorrhea, and anosmia, affecting the quality of life. Previous studies using MRI showed early onset and progression of CRS in CF patients from infancy to school age, as well as mid-term improvements in preschool and school-age CF children with lumacaftor/ivacaftor treatment. However, there is a lack of long-term data on the treatment effects on paranasal sinus abnormalities in CF children.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ummul Afia Shammi, Michelle Felicia D'Alessandro, Talissa Altes, F. William Hersman, Iulian C. Ruset, John Mugler, Craig Meyer, Jamie Mata, Kun Qing, Robert Thomen
Summary: This study compared hyperpolarized He-3 and Xe-129 images from patients with cystic fibrosis using different magnetic resonance sequences. The results showed that the choice of hyperpolarized Xe-129 or He-3 gas is inconsequential when it comes to measuring overall lung function by VDP, although Xe-129 may be more sensitive to starker lung defects, particularly when using a TrueFISP sequence.
ACADEMIC RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Anna Caroli, Giulia Villa, Paolo Brambilla, Matias Trillini, Kanishka Sharma, Sandro Sironi, Giuseppe Remuzzi, Norberto Perico, Andrea Remuzzi
Summary: This study presents and validates a diffusion MRI (DWI)-based method for quantifying total kidney and cyst volume (TCV) and characterizing non-cystic tissue microstructure in autosomal dominant polycystic kidney disease (ADPKD). DWI shows potential in ADPKD to assess and predict disease progression, evaluate the impact of novel therapies, and identify microcysts and peritubular interstitial fibrosis in non-cystic kidney tissue.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Christos Sachpekidis, Leyun Pan, Annette Kopp-Schneider, Vivienn Weru, Jessica C. C. Hassel, Antonia Dimitrakopoulou-Strauss
Summary: The study aims to determine an appropriate acquisition time range for the new long axial field of view Biograph Vision Quadra PET/CT scanner in melanoma patients. The results show that low-dose LAFOV PET/CT imaging is feasible and can provide comparable diagnostic data to standard lengths of acquisition in a shorter scanning time, which is significant for the diagnostic work-up of melanoma patients.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Oncology
Antonino A. A. Pane, Theresa Kordass, Agnes Hotz-Wagenblatt, Elke Dickes, Annette Kopp-Schneider, Rainer Will, Barbara Seliger, Wolfram Osen, Stefan B. B. Eichmueller
Summary: This study identified several miRNA species that can affect the susceptibility of melanoma cells to T cell-mediated killing. These miRNAs may represent attractive candidates for novel therapy approaches against melanoma and other tumors.
CLINICAL AND TRANSLATIONAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Jonas Albers, Willi L. Wagner, Mascha O. Fiedler, Anne Rothermel, Felix Wuennemann, Francesca Di Lillo, Diego Dreossi, Nicola Sodini, Elisa Baratella, Marco Confalonieri, Fulvia Arfelli, Armin Kalenka, Joachim Lotz, Juergen Biederer, Mark O. Wielpuetz, Hans-Ulrich Kauczor, Frauke Alves, Giuliana Tromba, Christian Dullin
Summary: Clinical computed tomography (CT) is the preferred imaging method for diagnosing lung diseases, but it has limitations in resolving microscopic structures. Propagation-based imaging (PBI), a phase-sensitive X-ray imaging technique, offers high-resolution imaging at lower radiation doses. In this study, technical refinements of PBI were presented for characterizing lung pathologies, demonstrating improved image quality compared to clinical CT. The combination of PBI and iodine k-edge subtraction imaging showed potential for analyzing lung perfusion in detail.
SCIENTIFIC REPORTS
(2023)
Article
Pharmacology & Pharmacy
Lena Wucherpfennig, Felix Wuennemann, Monika Eichinger, Angelika Seitz, Ingo Baumann, Mirjam Stahl, Simon Y. Graeber, Shengkai Zhao, Jaehi Chung, Jens-Peter Schenk, Abdulsattar Alrajab, Hans-Ulrich Kauczor, Marcus A. Mall, Olaf Sommerburg, Mark O. Wielpuetz
Summary: Chronic rhinosinusitis (CRS) in cystic fibrosis (CF) can cause nasal congestion, rhinorrhea, and anosmia, affecting the quality of life. Previous studies using MRI showed early onset and progression of CRS in CF patients from infancy to school age, as well as mid-term improvements in preschool and school-age CF children with lumacaftor/ivacaftor treatment. However, there is a lack of long-term data on the treatment effects on paranasal sinus abnormalities in CF children.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Julian Berges, Simon Y. Graeber, Susanne Haemmerling, Yin Yu, Arne Kruempelmann, Mirjam Stahl, Stephanie Hirtz, Heike Scheuermann, Marcus A. Mall, Olaf Sommerburg
Summary: In this prospective study, the effect of Lumacaftor/ivacaftor on CFTR biomarkers and clinical outcome parameters in CF patients aged 2-11 years was evaluated. The treatment significantly reduced sweat chloride concentration and improved CFTR activity, consistent with previous findings in older CF patients with F508del.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Linus Piehler, Ralf Thalemann, Christine Lehmann, Stephanie Thee, Jobst Roehmel, Zulfiya Syunyaeva, Mirjam Stahl, Marcus A. Mall, Simon Y. Graeber
Summary: Initiation of ETI improves symptoms of depression in adult patients with CF with at least one F508del allele. However, symptoms of anxiety do not change after short-term therapy with ETI.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Critical Care Medicine
Ahmet Z. Uluer, Gordon MacGregor, Pilar Azevedo, Veronica Indihar, Claire Keating, Marcus A. Mall, Edward F. McKone, Bonnie W. Ramsey, Steven M. Rowe, Ronald C. Rubenstein, Jennifer L. Taylor-Cousar, Elizabeth Tullis, Lael M. Yonker, Chenghao Chu, Anna P. Lam, Nitin Nair, Patrick R. Sosnay, Simon Tian, Fredrick Van Goor, Lakshmi Viswanathan, David Waltz, Linda T. Wang, Yingmei Xi, Joanne Billings, Alexander Horsley
Summary: This study demonstrates that once-daily dosing with vanzacaftor-tezacaftor-deutivacaftor is safe and effective in improving lung function and respiratory symptoms in patients with cystic fibrosis, and it enhances CFTR function.
LANCET RESPIRATORY MEDICINE
(2023)
Article
Computer Science, Artificial Intelligence
Tim Radsch, Annika Reinke, Vivienn Weru, Minu D. D. Tizabi, Nicholas Schreck, A. Emre Kavur, Buenyamin Pekdemir, Tobias Ross, Annette Kopp-Schneider, Lena Maier-Hein
Summary: Biomedical image analysis algorithm validation relies on high-quality annotation of reference datasets, which requires effective labelling instructions. However, there is a lack of optimization in this area. A systematic study of labelling instructions in the field of biomedical imaging reveals a discrepancy between annotators' needs and the current quality and availability of instructions. Analyzing a large dataset annotated by professional annotators and Amazon Mechanical Turk crowdworkers, it is found that including exemplary images significantly improves annotation performance compared to text-only descriptions, while solely extending text descriptions does not. Furthermore, professional annotators consistently outperform crowdworkers.
NATURE MACHINE INTELLIGENCE
(2023)
Letter
Respiratory System
Katie J. Bayfield, Oliver Weinheimer, Christie Boyton, Rachel Fitzpatrick, Anna Middleton, Brendan Kennedy, Anneliese Blaxland, Geshani Jayasuriya, Neil Caplain, Hana Issa, Robert Goetti, Mark O. Wielpuetz, Lifeng Yu, Craig J. Galban, Terry E. Robinson, Brian Bartholmai, Dominic Fitzgerald, Hiran Selvadurai, Paul D. Robinson
EUROPEAN RESPIRATORY JOURNAL
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Simon M. F. Triphan, Grzegorz Bauman, Philip O. Konietzke, Marilisa Konietzke, Mark Wielpuetz
Summary: Lung perfusion, an essential process for oxygenation, is regulated by hypoxic pulmonary vasoconstriction (HPV) in response to obstructive airway diseases. Various MRI techniques have been developed to visualize lung perfusion, and dynamic-contrast enhanced MRI is widely used in clinical assessment. Non-contrast techniques are still being researched and validated. Preliminary data on these techniques in evaluating therapy effects are emerging. Level of Evidence 5, Technical Efficacy Stage 5.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Critical Care Medicine
Nicole Mayer-Hamblett, John Paul Clancy, Raksha Jain, Scott H. Donaldson, Isabelle Fajac, Christopher H. Goss, Deepika Polineni, Felix Ratjen, Bradley S. Quon, Edith Zemanick, Scott C. Bell, Jane C. Davies, Manu Jain, Michael W. Konstan, Natanya R. Kerper, Tre LaRosa, Marcus A. Mall, Edward McKone, Kelsie Pearson, Joseph M. Pilewski, Lynne Quittell, Jonathan H. Rayment, Steven M. Rowe, Jennifer L. Taylor-Cousar, George Retsch-Bogart, Damian Downey
Summary: The use of modulator therapies for cystic fibrosis has changed clinical trial strategies, dividing the patient population based on eligibility. The development of nucleic acid-based therapies faces challenges due to limited resources and the inability to conduct placebo-controlled trials. Advancing symptomatic therapies is also difficult in a population already receiving modulator treatment.
LANCET RESPIRATORY MEDICINE
(2023)
Article
Respiratory System
Mirjam Stahl, Jobst Roehmel, Monika Eichinger, Felix Doellinger, Lutz Naehrlich, Matthias V. Kopp, Anna-Maria Dittrich, Christopher Lee, Olaf Sommerburg, Simon Tian, Tu Xu, Pan Wu, Aniket Joshi, Partha Ray, Margaret E. Duncan, Mark O. Wielputz, Marcus A. Mall
Summary: This study investigated the effects of LUM/IVA treatment on disease progression in children aged 2 to 5 years with CF. Results showed potential early disease modification with LUM/IVA, as indicated by improvements in chest MRI and various clinical markers. LUM/IVA treatment also led to improvements in lung function and growth parameters.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2023)
Article
Respiratory System
A. Susanne Dittrich, Markus Dumke, Ferdinand Kapl, Philipp Schneider, Sabine Wege, Simon Graeber, Mirjam Stahl, Felix J. Herth, Lutz Naehrlich, Marcus A. Mall, Olaf Sommburg
Summary: This study aimed to determine updated FEV1 and BMI percentiles for patients with cystic fibrosis (CF) and to study their dependence on mortality attrition. Age- and height-adjusted FEV1 and BMI percentiles were calculated from 4,947 CF patients aged 6-50 years from the German CF Registry for the period 2016-2019. The study found that FEV1 increased throughout childhood and decreased substantially during adulthood. The survival-adjusted percentiles were also estimated.
Article
Respiratory System
Lena Wucherpfennig, Felix Wuennemann, Monika Eichinger, Niclas Schmitt, Angelika Seitz, Ingo Baumann, Mirjam Stahl, Simon Y. Graeber, Jaehi Chung, Jens-Peter Schenk, Abdulsattar Alrajab, Hans-Ulrich Kauczor, Marcus A. Mall, Olaf Sommerburg, Mark O. Wielputz
Summary: This study longitudinally evaluated chronic rhinosinusitis (CRS) in children with cystic fibrosis (CF) using paranasal sinus magnetic resonance imaging (MRI). The results showed that CRS starts early in infancy and progresses in severity until school age. The study also found that lumacaftor/ivacaftor therapy can improve CRS in children with CF.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hila Tal Tamir, Dana Stav, Yitzhac Hadad, Rivka Kessner
Summary: This study aimed to characterize thyroid nodules seen on Spectral Detector computed tomography (SDCT) and compare them with their Thyroid Imaging Reporting and Data System (TI-RADS) category on Ultrasound (US). The results showed that the spectral results of SDCT can assist in differentiating thyroid nodules of different risk levels.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Volha Nizhnikava, Ursula Reiter, Gabor Kovacs, Clemens Reiter, Corina Kraeuter, Horst Olschewski, Michael Fuchsjaeger, Gert Reiter
Summary: The purpose of this study was to investigate the associations between cardiac magnetic resonance feature-tracking-derived myocardial strain parameters and volumetric function and hemodynamic parameters in patients with pulmonary hypertension. The results showed that impairment of myocardial strains was more strongly associated with alterations in ventricular function parameters than elevated pulmonary arterial pressure, limiting the diagnostic information of myocardial strain parameters in pulmonary hypertension.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ling Qian, Rui-lin Quan, Xiao-xi Chen, Yang-yi Lin, Xiao-li Jing, Qing Gu, Chang-ming Xiong, Jian-guo He, Ai-hua Zhi
Summary: The purpose of this study was to investigate the imaging characteristics and prognostic factors for the long-term survival of Behcet's disease (BD) with arterial involvement. The results showed that arterial lesions associated with BD usually involve multiple arteries and manifest differently in different types of arteries. Cardiac involvement and pulmonary artery aneurysm/dilation were independent prognostic factors for the survival of BD patients with arterial involvement.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Yong Xie, Jian Wang, Yinghua Zou
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daria Kifjak, Maximilian Hochmair, Daniel Sobotka, Alexander R. Haug, Raphael Ambros, Florian Prayer, Benedikt H. Heidinger, Sebastian Roehrich, Ruxandra-Iulia Milos, Wolfgang Wadsak, Thorsten Fuereder, Dagmar Krenbek, Andreas Fazekas, Michael Meilinger, Marius E. Mayerhoefer, Georg Langs, Christian Herold, Helmut Prosch, Lucian Beer
Summary: The ability of pretreatment PET parameters and peripheral blood biomarkers to predict PFS and OS in NSCLC patients treated with ICIT was assessed. The study found that MTV and the number of SOI were independent risk factors for progression and overall survival, and the combination of these factors improved risk stratification.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Theresa Sophie Patzer, Jan-Peter Grunz, Henner Huflage, Jan-Lucca Hennes, Pauline Pannenbecker, Philipp Gruschwitz, Saif Afat, Judith Herrmann, Thorsten Alexander Bley, Andreas Steven Kunz
Summary: This study investigated the potential of tin prefiltration and virtual monoenergetic imaging (VMI) in suppressing metal artifacts in high-resolution CT images of the lower extremities. The results showed that VMI reconstructions had better artifact reduction compared to T3D. VMI110keV had the least image noise. In terms of image quality, interpretability of bone-metal interface, and overall image quality, VMI110keV performed the best.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yue Li, Huan Zhang, Lei Yue, Caixia Fu, Robert Grimm, Wenhua Li, Weijian Guo, Tong Tong
Summary: This study evaluated and compared the diagnostic value of diffusion-related texture analysis parameters from different magnetic resonance diffusion models in predicting the clinical response to chemotherapy in patients with colorectal liver metastases. Among the models, DKI-derived parameters showed the best performance for early prediction, followed by IVIM-derived parameters and DWI baseline features.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Wang, ShiXiong Zhang, Jun Xin
Summary: This study aimed to determine if sex differences in abdominal visceral fat composition and metabolism can help predict the prognosis of DLBCL patients. The results showed that females with certain fat composition and metabolism characteristics had worse progression-free survival, while no significant differences were found in males with DLBCL.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ping Wu, Lan Wu, Jing Ou, Jin-ming Cao, Mao-yong Fu, Tian-wu Chen, Erika Ouchi, Jiani Hu
Summary: This study aimed to develop CT radiomics models to preoperatively identify lymph node (LN) status in resectable esophageal squamous cell carcinoma (ESCC) patients. The results showed that the combined model, integrating ESCC and LN radiomics features with clinical features, had the highest predictive ability among the three models. The combined model's predictive ability was validated in both the test and external validation cohorts.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)