Article
Clinical Neurology
Xiang Liu, Zhipeng Wei, Liting Chen, Wenfeng Duan, Haijun Li, Linghong Kong, Yongqiang Shu, Panmei Li, Kunyao Li, Wei Xie, Yaping Zeng, Ling Huang, Ting Long, Dechang Peng
Summary: The study reveals that patients with untreated obstructive sleep apnea (OSA) exhibit abnormal changes in white matter (WM) fibers, which are associated with cognitive impairment. However, short-term continuous positive airway pressure (CPAP) therapy does not result in reversible changes in WM microstructure.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neurosciences
Robert Steinbach, Nayana Gaur, Annekathrin Roediger, Thomas E. Mayer, Otto W. Witte, Tino Prell, Julian Grosskreutz
Summary: This study used the novel D50 model to investigate correlations between diffusion tensor imaging measures and ALS pathology. High disease aggressiveness patients showed specific white matter pathway abnormalities, and there were correlations between disease accumulation and DTI measures, especially in the early stages of the disease.
HUMAN BRAIN MAPPING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Monika Gloor, Michaela Andelova, Laura Gaetano, Athina Papadopoulou, Federico Burguet Villena, Till Sprenger, Ernst-Wilhelm Radue, Ludwig Kappos, Oliver Bieri, Meritxell Garcia
Summary: This study analyzed the potential of magnetization transfer imaging (MTI) and diffusion tensor imaging (DTI) for the detection and evolution of new multiple sclerosis (MS) lesions. The results showed that MTI provides more information than DTI and can detect tissue changes 2 to 4 months prior to their appearance on MRI.
EUROPEAN RADIOLOGY
(2023)
Article
Neurosciences
Diana Valdes Cabrera, Penelope Smyth, Gregg Blevins, Derek Emery, Christian Beaulieu
Summary: DTI and volumetric MRI revealed white matter and deep grey matter abnormalities in the limbic system of MS patients. The fornix, thalamus, and hippocampus displayed atrophy and/or abnormal diffusion metrics, with the fornix showing the most extensive changes, mainly in those with cognitive impairment. These findings suggest a strong correlation between microstructural abnormalities in the limbic system and cognitive deficits in MS.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Geriatrics & Gerontology
Yahui Ouyang, Dong Cui, Zilong Yuan, Zhipeng Liu, Qing Jiao, Tao Yin, Jianfeng Qiu
Summary: Population aging has led to a focus on changes in elderly brains, particularly in white matter fibers. This study used various parameters to analyze age-related changes in white matter fibers, finding significant differences in FA, MD, AD, and RD between young and middle-age groups. Deterministic fiber tracking showed a correlation between fiber length and age, with specific fibers identified as potential image markers for age-related white matter changes.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiali Shao, Xuewei Zhang, Wenrui Xu, Zhe Zhang, Jieying Zhang, Hua Guo, Tao Jiang, Weihong Zhang
Summary: The study found that NODDI has good reliability in evaluating epileptogenic tubers in TSC patients. ICVF showed advantages in detecting subtle epileptogenic tubers, and NODDI parameters have the potential to identify epileptogenicity.
EUROPEAN RADIOLOGY
(2021)
Article
Biophysics
Diana Valdes Cabrera, Gregg Blevins, Penelope Smyth, Derek Emery, Kevin Grant Solar, Christian Beaulieu
Summary: High-resolution DTI and T2 mapping revealed abnormalities in the hippocampus of patients with multiple sclerosis. In patients with cognitive impairment, higher MD and T2 values and lower FA and volume were observed. These abnormalities may be associated with demyelination, neuron loss, and/or inflammation.
NMR IN BIOMEDICINE
(2023)
Article
Geriatrics & Gerontology
Benjamin Yeske, Jiancheng Hou, Nagesh Adluru, Veena A. Nair, Vivek Prabhakaran
Summary: This study revealed significant structural differences in white matter regions associated with language production in young adults, compared to older adults who showed significant correlations between language production and MD values. This suggests that white matter structures play a crucial role in age-related changes in language production.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Clinical Neurology
Matthias Grothe, Katharina Jochem, Sebastian Strauss, Soenke Langner, Michael Kirsch, Kai Hoffeld, Iris Katharina Penner, Guy Nagels, Kai Klepzig, Martin Domin, Martin Lotze
Summary: The study found that the structural integrity of frontoparietal white matter tracts is associated with processing speed in MS patients, with frontoparietal tracts playing a crucial role in information processing speed. Additionally, disease disability and total white matter volume were the main factors associated with processing speed.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Olivia Foesleitner, Volker Sturm, Jennifer Hayes, Markus Weiler, Georges Sam, Brigitte Wildemann, Wolfgang Wick, Martin Bendszus, Sabine Heiland, Laura Bettina Jaeger
Summary: The study provides evidence of peripheral nerve involvement in multiple sclerosis at initial diagnosis, with a characteristic pattern indicating predominant demyelination and suggesting primary coaffection of the peripheral nervous system in MS. The use of DKI for peripheral nerves in this human study shows potential and clinical feasibility in providing novel biomarkers.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Franziska E. Hildesheim, Ralph H. B. Benedict, Robert Zivadinov, Michael G. Dwyer, Tom Fuchs, Dejan Jakimovski, Bianca Weinstock-Guttman, Niels Bergsland
Summary: NBM damage is associated with cognitive impairment in patients with multiple sclerosis, with diffusivity of NBM showing significant correlation with cognitive test results and ability to predict cognitive changes.
JOURNAL OF NEUROLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yan Xie, Yan Zhang, Yihao Yao, Dong Liu, Bo Chen, Wenzhen Zhu
Summary: The characteristics of optic nerve impairment in neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS) patients were assessed using fractional anisotropy (FA). The study found that FA values were significantly decreased in the optic nerves of NMOSD patients, especially in the posterior segment. FA values in the anterior and middle segments of the optic nerve were also decreased in MS patients. Significant differences in FA values were observed in the posterior segment between NMOSD and MS patients. The combination of FA and signal intensity ratio (SIR) showed good diagnostic performance in distinguishing between NMOSD and MS.
EUROPEAN RADIOLOGY
(2022)
Article
Neuroimaging
Anna J. E. Combes, Baxter P. Rogers, Kurt G. Schilling, Richard D. Lawless, Mereze Visagie, Delaney Houston, Logan Prock, Shekinah Malone, Sanjana Satish, Atlee A. Witt, Colin D. McKnight, Francesca Bagnato, John C. Gore, Seth A. Smith
Summary: Focal lesions can impact the functional connectivity of the ventral and dorsal networks in the cervical spinal cord of individuals with RRMS. This study examines the relationship between alterations in connectivity and damage in normal-appearing tissue. The results suggest that increased connectivity in response to structural damage may play a compensatory role in preserving sensory function in RRMS.
NEUROIMAGE-CLINICAL
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Homa Seyedmirzaei, Fardin Nabizadeh, Mohammad Hadi Aarabi, Lorenzo Pini
Summary: Diffusion-weighted imaging has been used to study alterations in multiple sclerosis (MS), and neurite orientation dispersion and density imaging (NODDI) is an emerging approach that quantifies specific neurite morphology. This systematic review summarized the NODDI findings in MS, identifying consistent alterations in NODDI metrics in white matter and grey matter lesions. Despite limitations, NODDI has the potential to reveal microstructural alterations in MS and improve our understanding of its pathophysiological mechanism.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Review
Neurosciences
Eleonora Tavazzi, Marta Cazzoli, Alice Pirastru, Valeria Blasi, Marco Rovaris, Niels Bergsland, Francesca Baglio
Summary: The review summarized studies on the impact of motor rehabilitation on brain neuroplasticity in multiple sclerosis patients. It was found that motor rehabilitation can promote clinical improvement and induce positive adaptive brain changes, but the effects may vary depending on the type of rehabilitation approach.
FRONTIERS IN NEUROSCIENCE
(2021)
Meeting Abstract
Cardiac & Cardiovascular Systems
E. Torac, S. L. Magda, D. Vinereanu, L. Gaman, I. Stoian, A. Torac, A. Roceanu, C. Bleotu, V. Atanasiu
Article
Clinical Neurology
Claudia Trenkwalder, K. Ray Chaudhuri, Pablo Martinez-Martin, Olivier Rascol, Reinhard Ehret, Martin Valis, Maria Satori, Anna Krygowska-Wajs, Maria J. Marti, Karen Reimer, Alexander Oksche, Mark Lomax, Julia DeCesare, Michael Hopp
Article
Clinical Neurology
Mihaela Onu, Liviu Badea, Adina Roceanu, Madalina Tivarus, Ovidiu Bajenaru
Article
Multidisciplinary Sciences
Liviu Badea, Mihaela Onu, Tao Wu, Adina Roceanu, Ovidiu Bajenaru
Correction
Multidisciplinary Sciences
Liviu Badea, Mihaela Onu, Tao Wu, Adina Roceanu, Ovidiu Bajenaru
Article
Clinical Neurology
Cosmin-Andrei Serban, Andrei Barborica, Adina-Maria Roceanu, Ioana Mindruta, Jan Ciurea, Alexandru C. Paslaru, Ana-Maria Zagrean, Leon Zagrean, Mihai Moldovan
Summary: The study aimed to assess the impairment of default mode network (DMN) reactivity in stroke patients with impaired consciousness using routine EEG recordings. The findings revealed DMN impairment in coma patients following an acute stroke, and the method used in this study could effectively detect it. This discovery is significant for monitoring DMN function at bedside.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Neurosciences
Andrei Barborica, Irina Oane, Cristian Donos, Andrei Daneasa, Felicia Mihai, Constantin Pistol, Aurelia Dabu, Adina Roceanu, Ioana Mindruta
Summary: Direct electrical stimulation (DES) is crucial for mapping cortical function and treating drug-resistant epilepsy, with evidence also showing the importance of remote activations. Introducing a new stimulation paradigm and signal analysis methodology can disambiguate EEG responses and highlight the networks associated with clinical effects, providing valuable insights for invasive exploration and seizure propagation patterns.
HUMAN BRAIN MAPPING
(2022)
Review
Clinical Neurology
Matteo Castaldo, Marta Waliszewska-Prosol, Maria Koutsokera, Micaela Robotti, Marcin Straburzynski, Loukia Apostolakopoulou, Mariarita Capizzi, Oneda Cibuku, Fidel Dominique Festin Ambat, Ilaria Frattale, Zukhra Gadzhieva, Erica Gallo, Anna Gryglas-Dworak, Gleni Halili, Asel Jusupova, Yana Koperskaya, Alo-Rainer Leheste, Maria Laura Manzo, Andrea Marcinno, Antonio Marino, Petr Mikulenka, Bee Eng Ong, Burcu Polat, Zvonimir Popovic, Eduardo Rivera-Mancilla, Adina Maria Roceanu, Eleonora Rollo, Marina Romozzi, Claudia Ruscitto, Fabrizio Scotto di Clemente, Sebastian Strauss, Valentina Taranta, Maria Terhart, Iryna Tychenko, Simone Vigneri, Blazej Misiak, Paolo Martelletti, Alberto Raggi
Summary: This study reviewed the incidence and characteristics of headache after COVID-19 vaccination. The results showed that the risk of developing headache doubled after vaccination, with no differences between different vaccine types. Some patients experienced pulsating headache with sensitivity to sound and light, and aggravation with activity.
JOURNAL OF HEADACHE AND PAIN
(2022)
Meeting Abstract
Clinical Neurology
Bogdan I. Pana, Andra Iosif, Adina Roceanu
Meeting Abstract
Clinical Neurology
A. Roceanu, A. Dragusin, O. A. Bajenaru
EUROPEAN JOURNAL OF NEUROLOGY
(2019)
Article
Neurosciences
Cosmin-Andrei Serban, Andrei Barborica, Adina-Maria Roceanu, Ioana-Raluca Mindruta, Jean Ciurea, Ana-Maria Zagrean, Leon Zagrean, Mihai Moldovan
PHYSICS OF THE MIND AND BRAIN DISORDERS: INTEGRATED NEURAL CIRCUITS SUPPORTING THE EMERGENCE OF MIND
(2017)
Meeting Abstract
Clinical Neurology
A. Daneasa, A. A. Arbune, A. M. Cobzaru, A. Roceanu
EUROPEAN JOURNAL OF NEUROLOGY
(2017)
Meeting Abstract
Clinical Neurology
A. Roceanu, O. A. Bajenaru
EUROPEAN JOURNAL OF NEUROLOGY
(2015)
Review
Pharmacology & Pharmacy
Adina Roceanu, Florina Antochi, Ovidiu Bajenaru
Article
Radiology, Nuclear Medicine & Medical Imaging
Hila Tal Tamir, Dana Stav, Yitzhac Hadad, Rivka Kessner
Summary: This study aimed to characterize thyroid nodules seen on Spectral Detector computed tomography (SDCT) and compare them with their Thyroid Imaging Reporting and Data System (TI-RADS) category on Ultrasound (US). The results showed that the spectral results of SDCT can assist in differentiating thyroid nodules of different risk levels.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Volha Nizhnikava, Ursula Reiter, Gabor Kovacs, Clemens Reiter, Corina Kraeuter, Horst Olschewski, Michael Fuchsjaeger, Gert Reiter
Summary: The purpose of this study was to investigate the associations between cardiac magnetic resonance feature-tracking-derived myocardial strain parameters and volumetric function and hemodynamic parameters in patients with pulmonary hypertension. The results showed that impairment of myocardial strains was more strongly associated with alterations in ventricular function parameters than elevated pulmonary arterial pressure, limiting the diagnostic information of myocardial strain parameters in pulmonary hypertension.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ling Qian, Rui-lin Quan, Xiao-xi Chen, Yang-yi Lin, Xiao-li Jing, Qing Gu, Chang-ming Xiong, Jian-guo He, Ai-hua Zhi
Summary: The purpose of this study was to investigate the imaging characteristics and prognostic factors for the long-term survival of Behcet's disease (BD) with arterial involvement. The results showed that arterial lesions associated with BD usually involve multiple arteries and manifest differently in different types of arteries. Cardiac involvement and pulmonary artery aneurysm/dilation were independent prognostic factors for the survival of BD patients with arterial involvement.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Yong Xie, Jian Wang, Yinghua Zou
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daria Kifjak, Maximilian Hochmair, Daniel Sobotka, Alexander R. Haug, Raphael Ambros, Florian Prayer, Benedikt H. Heidinger, Sebastian Roehrich, Ruxandra-Iulia Milos, Wolfgang Wadsak, Thorsten Fuereder, Dagmar Krenbek, Andreas Fazekas, Michael Meilinger, Marius E. Mayerhoefer, Georg Langs, Christian Herold, Helmut Prosch, Lucian Beer
Summary: The ability of pretreatment PET parameters and peripheral blood biomarkers to predict PFS and OS in NSCLC patients treated with ICIT was assessed. The study found that MTV and the number of SOI were independent risk factors for progression and overall survival, and the combination of these factors improved risk stratification.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Theresa Sophie Patzer, Jan-Peter Grunz, Henner Huflage, Jan-Lucca Hennes, Pauline Pannenbecker, Philipp Gruschwitz, Saif Afat, Judith Herrmann, Thorsten Alexander Bley, Andreas Steven Kunz
Summary: This study investigated the potential of tin prefiltration and virtual monoenergetic imaging (VMI) in suppressing metal artifacts in high-resolution CT images of the lower extremities. The results showed that VMI reconstructions had better artifact reduction compared to T3D. VMI110keV had the least image noise. In terms of image quality, interpretability of bone-metal interface, and overall image quality, VMI110keV performed the best.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yue Li, Huan Zhang, Lei Yue, Caixia Fu, Robert Grimm, Wenhua Li, Weijian Guo, Tong Tong
Summary: This study evaluated and compared the diagnostic value of diffusion-related texture analysis parameters from different magnetic resonance diffusion models in predicting the clinical response to chemotherapy in patients with colorectal liver metastases. Among the models, DKI-derived parameters showed the best performance for early prediction, followed by IVIM-derived parameters and DWI baseline features.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Wang, ShiXiong Zhang, Jun Xin
Summary: This study aimed to determine if sex differences in abdominal visceral fat composition and metabolism can help predict the prognosis of DLBCL patients. The results showed that females with certain fat composition and metabolism characteristics had worse progression-free survival, while no significant differences were found in males with DLBCL.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ping Wu, Lan Wu, Jing Ou, Jin-ming Cao, Mao-yong Fu, Tian-wu Chen, Erika Ouchi, Jiani Hu
Summary: This study aimed to develop CT radiomics models to preoperatively identify lymph node (LN) status in resectable esophageal squamous cell carcinoma (ESCC) patients. The results showed that the combined model, integrating ESCC and LN radiomics features with clinical features, had the highest predictive ability among the three models. The combined model's predictive ability was validated in both the test and external validation cohorts.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)