期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 137, 期 12, 页码 4038-4041出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja512658m
关键词
-
资金
- Academy of Finland [139550, 276586]
- Inorganic Materials Chemistry Graduate Program, COST Action [CM0905]
- Hungarian Scientific Research Fund (OTKA) [K-81927]
- Academy of Finland (AKA) [139550, 276586, 276586, 139550] Funding Source: Academy of Finland (AKA)
We report the synthesis and reactivity of a chiral aminoborane displaying both rapid and reversible H-2 activation. The catalyst shows exceptional reactivity in asymmetric hydrogenation of enamines and unhindered imines with stereoselectivities of up to 99% ee. DFT analysis of the reaction mechanism pointed to the importance of both repulsive steric and stabilizing intermolecular non-covalent forces in the stereodetermining hydride transfer step of the catalytic cycle.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据