Article
Physics, Fluids & Plasmas
R. Mark Bradley, Patrick D. Shipman
Summary: In this study, the patterns created by scanning an atomic force microscope tip over a polymer surface were investigated using a mesoscopic model. The research discovered that the steady-state solution is only stable below a critical value, beyond which periodic stick-slip motion occurs.
Article
Physics, Applied
Gwangmook Kim, YoungJun Cho, Min-Kyun Cho, Dohun Kim, Wooyoung Shim
Summary: Cantilever-free scanning probe microscopy has potential for high-throughput topography imaging. However, the current imaging mechanism lacks efficiency in detection precision and bandwidth, limiting the application of this measurement system. We present a contact resistance-based imaging system using RF reflectometry, achieving sub-micrometer-scale topography imaging with a resolution of 230 nm and a bandwidth of approximately 8.5 MHz.
JOURNAL OF APPLIED PHYSICS
(2023)
Article
Biochemistry & Molecular Biology
Joshua A. Grosser, Margaret E. Maes, Robert W. Nickells
Summary: Recent advancements in live cell imaging technologies have revealed the intracellular propagation of late apoptotic events, shedding light on the critical role of the BAX protein in apoptosis propagation.
Article
Chemistry, Analytical
Luke Oduor Otieno, Bernard Ouma Alunda, Jaehyun Kim, Yong Joong Lee
Summary: Improving the imaging rate of a high-speed atomic force microscope requires specialized hardware and software, with ongoing efforts to enhance general applications. A compact HS-AFM scan-head design with minimal Z-scanner loading is presented in this study as an efficient solution for faster imaging.
Article
Biophysics
Maria Pedrosa, Julia Maldonado-Valderrama, Maria Jose Galvez-Ruiz
Summary: This study investigates the interactions between curcumin, a bioactive natural compound with anti-cancer properties, and both healthy and cancerous cell membrane models. The results show that curcumin has a destabilizing effect on the cancerous cell membrane model, while enhancing cohesion in the healthy membrane model. These findings are valuable for improving the selectivity of drugs and avoiding adverse side effects of current anticancer therapies.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Physics, Fluids & Plasmas
Pedro J. Martinez, Enrico Gnecco, Juan J. Mazo
Summary: This study investigates the quantifiable characteristics of wave-like features observed on polymer surfaces when examined with AFM, and demonstrates the presence of ripples and dotted regions under different parameter values. The amplitude, period, and orientation of these features are numerically estimated, revealing a cooperative process involving the scanning of multiple lines leading to the emergence of ripples.
Article
Chemistry, Physical
Francisco J. Solis, Monica Olvera de la Cruz
Summary: This article discusses the interactions between charged particles and induced polarization charge on solid-liquid or liquid-liquid interfaces with dielectric contrast, as well as the self-energy of charged particles near rough surfaces. Results show that the local convexity and concavity of the surface affect the repulsion of ions.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Engineering, Chemical
Chenwei Li, Yating Zhang, Haijun Zhang
Summary: Nanobubbles on the solid surface play a crucial role in the removal of fine coal/minerals from slurry. This study investigates the nucleation process of surface nanobubbles and its effect on particle interaction. The findings reveal that surface hydrophobicity is more important than surface roughness in nanobubbles nucleation. The presence of nanobubbles enhances adhesion force and collision probability, leading to improved removal efficiency in flotation techniques.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Review
Chemistry, Physical
Andrius Dzedzickis, Juste Rozene, Vytautas Bucinskas, Darius Virzonis, Inga Morkvenaite-Vilkonciene
Summary: This paper provides a systematic review of atomic force microscopy (AFM), focusing on analyzing the available technical solutions and design of different parts, particularly the cantilever. Many recent scientific articles propose innovative AFM control and imaging algorithms, some of which are based on artificial intelligence.
Article
Physics, Applied
D. F. S. Costa, J. L. B. de Araujo, C. L. N. Oliveira, J. S. de Sousa
Summary: This work presents an analytical model for describing atomic force microscopy force curves of standard linear solid and power-law viscoelastic materials, considering the effects of indenter geometry and finite thickness. It is found that conical/pyramidal cantilevers are less affected by finite thickness effects compared to other shapes, such as spherical and flat punch indenters. Finite element modeling of the stress field distribution within the sample confirms this. The study also analyzes systematic errors when analyzing finite thickness samples with an infinite thickness force model, showing that for spherical indenters and indentation depths up to 20% of sample thickness, the mechanical response of viscoelastic materials will inaccurately resemble purely elastic behavior, even within timescales where viscoelastic relaxation should occur.
JOURNAL OF APPLIED PHYSICS
(2022)
Article
Multidisciplinary Sciences
Xuanyu Huang, Xiaojian Xiang, Jinghui Nie, Deli Peng, Fuwei Yang, Zhanghui Wu, Haiyang Jiang, Zhiping Xu, Quanshui Zheng
Summary: The article introduces a microscale generator - the Schottky superlubric generator (S-SLG), which can generate high current and power densities while maintaining stable high electrical current density over a long lifetime. Experimental results demonstrate the enduring and virtually unlimited persistence of the S-SLG.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
N. Makarova, I Sokolov
Summary: The brush model provides a consistent interpretation of AFM indentation data by considering a non-Hertzian deformation of the pericellular brush-like layer and provides a less depth-dependent measurement of the effective Young's modulus of the cell body. The model is robust and the errors due to uncertainties in the model and experimental data are within 4%.
Article
Chemistry, Physical
Haitao Zhang, Cai Shen, Yunbo Huang, Zhaoping Liu
Summary: The spontaneous formation of solid electrolyte interphase (s-SEI) on the surface of lithium metal was reported in this study. Differences in the properties of the s-SEI layers formed in different electrolytes were investigated, showing that the composition mainly consisted of LiF, Li3N, ROCO2Li, and ROLi. Thicker s-SEI layers were found to increase the polarization potential of plating/stripping, while Li3N-riched s-SEI reduced the polarization potential.
APPLIED SURFACE SCIENCE
(2021)
Article
Engineering, Mechanical
Yanquan Geng, Junshuai Jia, Zihan Li, Yu Liu, Jiqiang Wang, Yongda Yan, Yang Gan
Summary: The study introduced a nanomachining method using a dual-tip probe and single-crystal copper as the sample material, successfully machining symmetrical three-dimensional nanostructures. A depth prediction model accurately predicted the nanoscratching process, but inaccuracies were observed at smaller machined depths.
INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES
(2021)
Article
Biophysics
Csilla Fazakas, Mihaly Kozma, Kinga Molnar, Andras Kincses, Andras Der, Adrienn Fejer, Barnabas Horvath, Imola Wilhelm, Istvan A. Krizbai, Attila G. Vegh
Summary: Brain metastases are a feared complication of cancer, with breast adenocarcinoma being one of the leading sources. Research shows that exosomes derived from breast adenocarcinoma can affect the adhesion strength between cancer cells and brain endothelium.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Review
Biochemistry & Molecular Biology
Jinhuan Jiang, Jiang Pi, Jiye Cai
BIOINORGANIC CHEMISTRY AND APPLICATIONS
(2018)
Article
Medicine, Research & Experimental
Fen Yang, Xiaohui Su, Jiang Pi, Kangsheng Liao, Hua Zhou, Yang Sun, Juan Liu, Xiaoxia Guo, Jinhuan Jiang, Hua Jin, Jiye Cai, Ting Li, Liang Liu
BIOMEDICINE & PHARMACOTHERAPY
(2018)
Article
Chemistry, Analytical
Huimei Liu, Baocheng Wang, Dehai Li, Xueyi Zeng, Xiao Tang, Qingsheng Gao, Jiye Cai, Huai-hong Cai
Article
Pathology
Jin-Huan Jiang, Jiang Pi, Hua Jin, Fen Yang, Ji-Ye Cai
PATHOLOGY RESEARCH AND PRACTICE
(2018)
Article
Biochemistry & Molecular Biology
Jin-Huan Jiang, Jiang Pi, Hua Jin, Ji-Ye Cai
JOURNAL OF CELLULAR BIOCHEMISTRY
(2019)
Article
Biotechnology & Applied Microbiology
Jin-Huan Jiang, Jiang Pi, Hua Jin, Ji-Ye Cai
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Sui-Ping Deng, Yi-Li Yang, Xing-Xing Cheng, Wen-Rong Li, Ji-Ye Cai
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2019)
Article
Materials Science, Biomaterials
Jiang Pi, Ling Shen, Hongbo Shen, Enzhuo Yang, Wandang Wang, Richard Wang, Dan Huang, Bao-Shiang Lee, Chunmiao Hu, Crystal Chen, Hua Jin, Jiye Cai, Gucheng Zeng, Zheng W. Chen
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2019)
Article
Chemistry, Multidisciplinary
Jiang Pi, Ling Shen, Enzhuo Yang, Hongbo Shen, Dan Huang, Richard Wang, Chunmiao Hu, Hua Jin, Huaihong Cai, Jiye Cai, Gucheng Zeng, Zheng W. Chen
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2020)
Article
Biochemistry & Molecular Biology
Xiaokun Wang, Dongjuan Qiao, Likun Chen, Meng Xu, Shupeng Chen, Liyan Huang, Fang Wang, Zhen Chen, Jiye Cai, Liwu Fu
Article
Pathology
Jin-Huan Jiang, Jiang Pi, Ji-Ye Cai
PATHOLOGY RESEARCH AND PRACTICE
(2020)
Article
Engineering, Biomedical
Xueqin Huang, Huaihong Cai, Haibo Zhou, Ting Li, Hua Jin, Colin E. Evans, Jiye Cai, Jiang Pi
Summary: Manipulating protein degradation pathways such as ALP and UPS with Co3O4 NPs can enhance anticancer treatments by inducing autolysosome accumulation and inhibiting lysosomal proteolytic activity. Combining Co3O4 NPs with proteasome inhibitors also promotes the accumulation of autophagic substrates and protein ubiquitination to inhibit cancer progression. Additionally, leveraging the photothermal conversion efficiency of Co3O4 NPs enhances the anticancer efficacy of existing treatments in vitro and in vivo.
ACTA BIOMATERIALIA
(2021)
Article
Pharmacology & Pharmacy
Ke Changhong, Yuan Peng, Zhengqiang Yuan, Jiye Cai
Summary: The study found that ginsenoside Rb1 can protect cells from Aβ-induced cytotoxicity, acting as an agonist of PPARγ to reduce cholesterol levels in AD model cells. Lowering cholesterol levels reduced Aβ-induced cytotoxicity.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Jiang Pi, Jinhuan Jiang, Huaihong Cai, Fen Yang, Hua Jin, Peihui Yang, Jiye Cai, Zheng W. Chen
Article
Biochemistry & Molecular Biology
Aiqun Li, Jianwei Chen, Zhi-Hong Liang, Jiye Cai, Huai-Hong Cai, Min Chen
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2017)