1,2,3-Triazole in Heterocyclic Compounds, Endowed with Biological Activity, through 1,3-Dipolar Cycloadditions

DNA-binding of nickel(II), copper(II) and zinc(II) complexes: Structure–affinity relationships

(2013) Giampaolo Barone et al.   COORDINATION CHEMISTRY REVIEWS

Synthesis and cytotoxic activity on human cancer cells of carbamate derivatives of 4β-(1,2,3-triazol-1-yl)podophyllotoxin

(2013) Jian-Fei Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives: The effect on apoptosis induction, cell cycle and proliferation

(2013) Francesco Mingoia et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 3-O-propargylated betulinic acid and its 1,2,3-triazoles as potential apoptotic agents

(2013) Rabiya Majeed et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An unexpected Dimroth rearrangement leading to annelated thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with potent antitumor activity

(2013) Antonino Lauria et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New annelated thieno[2,3- e ][1,2,3]triazolo[1,5- a ]pyrimidines, with potent anticancer activity, designed through VLAK protocol

(2013) Antonino Lauria et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and biological evaluation of new 2′-deoxy-2′-fluoro-4′-triazole cytidine nucleosides as potent antiviral agents

(2013) Jie Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The influence of substitution in the quinoxaline nucleus on 1,3-dipolar cycloaddition reactions: A DFT study

(2013) Antonino Lauria et al.   Computational and Theoretical Chemistry

Targeting Glioblastoma Stem Cells: Cell Surface Markers

(2012) J. He et al.   CURRENT MEDICINAL CHEMISTRY

Lead optimization through VLAK protocol: New annelated pyrrolo-pyrimidine derivatives as antitumor agents

(2012) Antonino Lauria et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The impact of click chemistry in medicinal chemistry

(2012) Jingli Hou et al.   Expert Opinion on Drug Discovery

Moderating Strain without Sacrificing Reactivity: Design of Fast and Tunable Noncatalyzed Alkyne–Azide Cycloadditions via Stereoelectronically Controlled Transition State Stabilization

(2012) Brian Gold et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regio- and Stereoselective Synthesis of a Library of Bioactive Dispiro-Oxindolo/Acenaphthoquino Andrographolides via 1,3-Dipolar Cycloaddition Reaction Under Microwave Irradiation

(2012) Abhijit Hazra et al.   ACS Combinatorial Science

AChE inhibitor : A regio- and stereo-selective 1,3-dipolar cycloaddition for the synthesis of novel substituted 5,6-dimethoxy spiro[5.3′]-oxindole-spiro-[6.3″]-2,3-dihydro-1H-inden-1″-one-7-(substituted aryl)-tetrahydro-1H-pyrrolo[1,2-c][1,3]thiazole

(2011) Mohamed Ashraf Ali et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Virtual lock-and-key approach: The in silico revival of Fischer model by means of molecular descriptors

(2011) Antonino Lauria et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 4β-triazole-podophyllotoxin derivatives by azide–alkyne cycloaddition and biological evaluation as potential antitumor agents

(2011) Hong Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Triazole-Epothilones by Using Cu2O Nanoparticles to Catalyze 1,3-Dipolar Cycloaddition

(2011) Xiyan Duan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Selective Formation of 1,5-Substituted Sulfonyl Triazoles Using Acetylides and Sulfonyl Azides

(2011) Maria Elena Meza-Aviña et al.   ORGANIC LETTERS

Stabilized Copper(I) Oxide Nanoparticles Catalyze Azide-Alkyne Click Reactions in Water

(2010) Zhenfang Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Substituted spiro [2.3′] oxindolespiro [3.2″]-5,6-dimethoxy-indane-1″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase

(2010) Mohamed Ashraf Ali et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, Biological Activity, and Molecular Modeling Studies of 1H-1,2,3-Triazole Derivatives of Carbohydrates as α-Glucosidases Inhibitors

(2010) Sabrina B. Ferreira et al.   JOURNAL OF MEDICINAL CHEMISTRY

Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2)

(2010) Xian Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

D-ring substituted 1,2,3-triazolyl 20-keto pregnenanes as potential anticancer agents: Synthesis and biological evaluation

(2010) Abid H. Banday et al.   STEROIDS

Copper-free click conjugation of methotrexate to a PAMAM dendrimer platform

(2010) Baohua Huang et al.   TETRAHEDRON LETTERS

Click Chemistry beyond Metal-Catalyzed Cycloaddition

(2009) C. Remzi Becer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu(I)-Catalyzed Huisgen Azide−Alkyne 1,3-Dipolar Cycloaddition Reaction in Nucleoside, Nucleotide, and Oligonucleotide Chemistry

(2009) Franck Amblard et al.   CHEMICAL REVIEWS

High-throughput synthesis of azide libraries suitable for direct “click” chemistry and in situ screening

(2009) Rajavel Srinivasan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A facile and regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles using click chemistry

(2009) Dalip Kumar et al.   TETRAHEDRON LETTERS

Design and Synthesis of 4-Substituted Indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine Derivatives with Antitumor Activity

(2008) Antonino Lauria et al.   JOURNAL OF MEDICINAL CHEMISTRY

Click Chemistry, A Powerful Tool for Pharmaceutical Sciences

(2008) Christopher D. Hein et al.   PHARMACEUTICAL RESEARCH

Preparation of ribavirin analogues by copper- and ruthenium-catalyzed azide-alkyne 1,3-dipolar cycloaddition

(2008) Ugo Pradere et al.   TETRAHEDRON

Click chemistry reactions in medicinal chemistry: Applications of the 1,3-dipolar cycloaddition between azides and alkynes

(2007) Gian Cesare Tron et al.   MEDICINAL RESEARCH REVIEWS