Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5+1] Double Michael Reactions

Catalytic Asymmetric Construction of Spirocycles Containing Pyrrolidine Motifs and Spiro Quaternary Stereogenic Centers via 1,3-Dipolar Cycloaddition of Azomethine Ylides with 2-Alkylidene-Cycloketones

(2011) Tang-Lin Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

A highly organocatalytic stereoselective double Michael reaction: efficient construction of optically enriched spirocyclic oxindoles

(2011) Liang-Liang Wang et al.   CHEMICAL COMMUNICATIONS

Stereoselective construction of a 5-aza-spiro[2,4]heptane motif via catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides and ethyl cyclopropylidene acetate

(2011) Tang-Lin Liu et al.   CHEMICAL COMMUNICATIONS

Efficient synthesis of optically active 4-nitro-cyclohexanones via bifunctional thiourea-base catalyzed double-Michael addition of nitromethane to dienones

(2011) Bin Wu et al.   CHEMICAL COMMUNICATIONS

Highly efficient construction of spirocyclic chromanone–pyrrolidines via Cu(i)/TF–BiphamPhos-catalyzed asymmetric 1,3-dipolar cycloaddition

(2011) Tang-Lin Liu et al.   CHEMICAL COMMUNICATIONS

Quinine-Catalysed Double Michael Addition of Malononitrile to 1,5-Disubstituted Pentadien-3-ones: A Stereoselective Route to Cyclohexanones

(2011) Claudia De Fusco et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Core-Structure-Motivated Design of a Phosphine-Catalyzed [3 + 2] Cycloaddition Reaction: Enantioselective Syntheses of Spirocyclopenteneoxindoles

(2011) Bin Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective cascade synthesis of spiropyrazolones

(2011) Alex Zea et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters

(2011) Wen-Bing Chen et al.   ORGANIC LETTERS

Chiral Counteranion Synergistic Organocatalysis under High Temperature: Efficient Construction of Optically Pure Spiro[cyclohexanone-oxindole] Backbone

(2011) Yu-Bao Lan et al.   ORGANIC LETTERS

Highly organocatalytic asymmetric Michael–ketone aldol–dehydration domino reaction: straightforward approach to construct six-membered spirocyclic oxindoles

(2010) Liang-Liang Wang et al.   CHEMICAL COMMUNICATIONS

Organocatalytic synthesis of spiro compounds via a cascade Michael–Michael-aldol reaction

(2010) Xavier Companyó et al.   CHEMICAL COMMUNICATIONS

Sulfones: new reagents in organocatalysis

(2010) Andrea-Nekane R. Alba et al.   CHEMICAL SOCIETY REVIEWS

Organocatalytic Tandem Reaction to Construct Six-Membered Spirocyclic Oxindoles with Multiple Chiral Centres through a Formal [2+2+2] Annulation

(2010) Kun Jiang et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Unique Approach to the Concise Synthesis of Highly Optically Active Spirooxazolines and the Discovery of a More Potent Oxindole-Type Phytoalexin Analogue

(2010) Xianxing Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Microwave-Assisted One-Pot Synthesis of Pyrazolone Derivatives under Solvent-Free Conditions

(2010) Ruoqun Ma et al.   MOLECULES

Asymmetric organocatalysis in total synthesis – a trial by fire

(2010) Eugenia Marqués-López et al.   NATURAL PRODUCT REPORTS

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Catalytic asymmetric 1,3-dipolar cycloaddition of N-unprotected 2-oxoindolin-3-ylidene derivatives and azomethine ylides for the construction of spirooxindole-pyrrolidines

(2010) Tang-Lin Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Quadruple Aminocatalytic Domino Reactions to Fused Carbocycles Incorporating a Spirooxindole Motif

(2010) Kun Jiang et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Formal [4 + 2] Cycloaddition for the Synthesis of Spiro[4-cyclohexanone-1,3′-oxindoline] Derivatives in High Optical Purity

(2010) Qiang Wei et al.   ORGANIC LETTERS

Highly Enantioselective Construction of Spiro[4H-pyran-3,3′-oxindoles] Through a Domino Knoevenagel/Michael/Cyclization Sequence Catalyzed by Cupreine

(2010) Wen-Bing Chen et al.   ORGANIC LETTERS

Asymmetric Organocatalytic Double-Conjugate Addition of Malononitrile to Dienones: Efficient Synthesis of Optically Active Cyclohexanones

(2010) Xue-ming Li et al.   ORGANIC LETTERS

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Synthesis and antiviral activity of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) against peste des petits ruminant virus (PPRV)

(2009) Kuppusamy Sujatha et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Front cover

(2009)   CHEMICAL SOCIETY REVIEWS

Organocatalysis—after the gold rush

(2009) Søren Bertelsen et al.   CHEMICAL SOCIETY REVIEWS

Organocatalytic Domino Reactions

(2009) Andrea-Nekane Alba et al.   CURRENT ORGANIC CHEMISTRY

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

Selected Synthetic Strategies to Spirocyclics

(2009) Sambasivarao Kotha et al.   SYNTHESIS-STUTTGART

Natural Products, Small Molecules, and Genetics in Tuberculosis Drug Development

(2008) Maria-Teresa Gutierrez-Lugo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Asymmetric Epoxidation of Cyclic Enones

(2008) Xingwang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The advent and development of organocatalysis

(2008) David W. C. MacMillan   NATURE

Natural products as inspiration for the development of asymmetric catalysis

(2008) Justin T. Mohr et al.   NATURE

Organocatalysis: asymmetric cascade reactions catalysed by chiral secondary amines

(2008) Xinhong Yu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety

(2007) Samir Bondock et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY