Article
Chemistry, Multidisciplinary
Muhammad Ali, Evgeny Kataev, Johannes Mueller, Hyoungwon Park, Marcus Halik, Andreas Hirsch
Summary: The study focuses on hydrogen bonding interactions at the level of functionalized nanoparticles, showing enhanced binding affinities through orthogonal functionalization using receptors with multiple hydrogen bonding motifs. The modified surfaces of superparamagnetic iron oxide nanoparticles were fully characterized, with the number of attached ligands determined. The host-guest interactions on the surface showed significantly stronger binding affinities compared to molecular interactions in solution.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Physical
Liya Dai, Pengyao Xing, Aiyou Hao
Summary: In this study, the aryl-group achiral molecular tweezers were found to effectively include chiral guest molecules via halogen bonding and other noncovalent interactions. Experimental and computational calculations revealed the formation of stable 1:1 host-guest complexes, demonstrating the transfer of chirality to achiral host molecules at the supramolecular level.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Chemistry, Multidisciplinary
Oscar Francesconi, Francesco Milanesi, Cristina Nativi, Stefano Roelens
Summary: In designing new biomimetic receptors for carbohydrates, shape-persistent macrocyclic structures are commonly chosen for effective recognition of neutral saccharides in water. However, this study found that acyclic receptors, while less explored, provide advantages in terms of selectivity for recognizing important 1,4-disaccharides in biological contexts. NMR spectroscopic data and molecular modeling calculations were used to analyze the differences in binding mode and shed light on the origin of recognition efficacy and selectivity.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Hyejin Kwon, Brian S. Newell, Carson J. Bruns
Summary: Cycloparaphenylene nanocarbons (CPPs) are organic semiconductors with controllable structures and unique optoelectronic properties. In this study, CH-pi interactions were found to enable the inclusion of redox-active metallocene guests in CPPs, enhancing stability through additional supramolecular forces. This finding is significant for the design of bespoke nanoelectronics and artificial molecular machines.
Article
Chemistry, Multidisciplinary
Fred C. Parks, Edward G. Sheetz, Sydney R. Stutsman, Alketa Lutolli, Sibali Debnath, Krishnan Raghavachari, Amar H. Flood
Summary: Preorganization is a crucial concept in supramolecular chemistry, where preorganized receptors enhance binding by minimizing the organization costs. This study presents a method to quantify the hidden costs of receptor organization and confirms the impact of solvent polarity on complex stability and conformational organization.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Jacobs H. Jordan, Henry S. Ashbaugh, Joel T. Mague, Bruce C. Gibb
Summary: There are still many unresolved questions regarding the supramolecular properties of ions in water, and the mathematical models used by supramolecular chemists do not adequately account for screening effects. The study shows that both screening and competitive binding have significant impacts on affinity in buffered solutions, especially when the ionic strength changes significantly. The competitive mathematical model proposed in the study suggests that competitive binding to the host is a major factor for binding attenuation in buffer systems, outweighing the effect of screening.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Helena Butkiewicz, Sandra Kosiorek, Volodymyr Sashuk, Oksana Danylyuk
Summary: The study explores the use of carboxylated pillar[5]arene in solid-state supramolecular chemistry, revealing its inclusion and self-assembly behavior in forming crystalline host-guest complexes with viologen derivatives. The unique distribution of carboxylic and carboxylate substituents on pillar[5]arene allows for self-assembly via different supramolecular synthons.
Article
Nanoscience & Nanotechnology
Tu Thi Kim Cuc, Pham Quoc Nhien, Trang Manh Khang, Hao-Yu Chen, Chia-Hua Wu, Bui-Thi Buu Hue, Yaw-Kuen Li, Judy Wu, Hong-Cheu Lin
Summary: The novel supramolecular host-guest systems exhibited interesting photoluminescence properties in DMF/H2O solutions, including bifluorophoric behavior after aluminum detection. Notably, Forster resonance energy transfer processes occurred between blue-emissive TPE donors and green-emissive fluorescein acceptors, resulting in strong green emissions. These systems showed high sensitivities and selectivities toward aluminum ions with effective FRET processes, making them promising for aluminum detection applications.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Applied
Rui Liu, Xiaoli Qin, Xiong Liu, Yonghua Wang, Jinfeng Zhong
Summary: The physicochemical properties and interactions of the complex of oleic acid (OA) and beta-cyclodextrin (beta-CD) were studied using experimental and computational methods. The study confirmed the stability improvement of the OA/beta-CD complex and the formation of hydrogen bonds between the carboxyl group of OA and the beta-CD cavity. This research provides a theoretical basis for the development of nutritional supplements containing unsaturated fatty acids encapsulated by beta-CD.
Article
Chemistry, Physical
Andre Nicolai Petelski, Josefina Marquez, Silvana Carina Pamies, Gladis Laura Sosa, Nelida Maria Peruchena
Summary: Four structural features of barbiturates and covalent decorations at the methylene group are responsible for certain anion affinity; C-H bond is as effective as N-H bond in coordinating chloride ions; acidity of C-H bond is mainly governed by orbital interaction energy when the methylene group moves out of the ring plane. The best choice is to coordinate ions when amide and carboxyl groups act together with C-H bond.
Article
Engineering, Environmental
Nannan Liu, Yanyan Pan, Yunxiang Lei, Miaochang Liu, Chengdong Peng, Zhengxu Cai, Guomin Shen, Huayue Wu, Xiaobo Huang, Yuping Dong
Summary: In this study, diphenyl sulfoxide was used as the host, and 1,3-diphenylbenzofuro[2,3-c]pyridine was designed as the guest to construct a new phosphorescence doped system. The addition of water, phenol, benzoic acid, and phenylboronic acid as the third component improved the phosphorescence performance. The phosphorescence quantum yields and lifetimes were significantly increased.
CHEMICAL ENGINEERING JOURNAL
(2022)
Review
Chemistry, Multidisciplinary
Siyun Zhang, Imene Boussouar, Haibing Li
Summary: The article discusses recent advancements in macrocyclic host-based nanochannels for the selective sensing and transport of ionic and chiral guests, highlighting the similarities and differences between different types of macrocyclic host-based nanochannels, and anticipating future research directions and application prospects.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Inorganic & Nuclear
Weibin Yu, Feng-Yi Qiu, Shi-Ting Luo, Hua-Tian Shi, Guozan Yuan, Xianwen Wei
Summary: Researchers have successfully constructed a triply interlocked [2]catenane with confirmed solid-state structure and solution properties, showing potential applications in drug delivery systems.
INORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Multidisciplinary
Yoko Sakata, Masahiro Okada, Shigehisa Akine
Summary: The binding behavior of macrocyclic hosts is greatly influenced by their shapes and sizes, allowing for control over guest uptake/release by opening/closing the host apertures. A post-metalation modification method can be used to achieve the open/close conversions, with Na+ significantly accelerating the gate-opening process. The binding of Na+ is also enhanced by the gate-opening, demonstrating the potential for manipulation of host-guest interactions.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Review
Chemistry, Multidisciplinary
Zhao Chen, Qiang He, Xiaowen Deng, Jiehai Peng, Kui Du, Yue Sun
Summary: Biological channels in cell membranes are critical for signal transduction and transmembrane transport regulation. Researchers are developing biomimetic nanochannels to imitate these processes. Unlike fragile biological channels, solid nanochannels have gained interest for their controllable surface chemistry and superior mechanical properties. Surface functionalization with macrocyclic hosts enhances the properties of solid nanochannels, such as stimuli response and separation capabilities. This review summarizes recent advances in nanochannel membranes decorated with macrocyclic host-guest chemistry, covering various responsive nanochannels and separation applications.
CHEMICAL COMMUNICATIONS
(2023)
