Sequential 1,3-Dipolar Cycloaddition of Nitrones to β-(2-Aminophenyl) α,β-Ynones and Cyclocondensation: A New Entry to the Isoxazolino[4,5-c]quinoline Ring

The reaction of beta-(2-aminophenyl) alpha,beta-ynones with N-methyl nitrones provides a simple and efficient entry to the isoxazolino[4,5-c]quinoline ring system through a sequential 1,3-dipolar cycloaddition/anmulation process. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)