Fluorescent Cyclohexyl-Based Chemosensors for Selective Sensing of TMA Malonate in DMSO/Water

Two new cyclohexyl-based fluorescent thioureas have been synthesized. The prepared ligands contain either a fluorescein or a rhodamine B moiety that are used as signalling units in dicarboxylate recognition. An equimolecular mixture of both ligands selectively recognize malonate in a competitive buffered medium. An inhibition of FRET as a result of the complex geometry might be proposed as a transduction mechanism in the sensing process. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)