Phase-II metabolism limits the antiproliferative activity of urolithins in human colon cancer cells

The Gut Microbiota Ellagic Acid-Derived Metabolite Urolithin A and Its Sulfate Conjugate Are Substrates for the Drug Efflux Transporter Breast Cancer Resistance Protein (ABCG2/BCRP)

(2013) Antonio González-Sarrías et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death

(2013) Virginie Aires et al.   MOLECULAR NUTRITION & FOOD RESEARCH

ABC transporters and their role in nucleoside and nucleotide drug resistance

(2012) Yu Fukuda et al.   BIOCHEMICAL PHARMACOLOGY

Intestinal Ellagitannin Metabolites Ameliorate Cytokine-Induced Inflammation and Associated Molecular Markers in Human Colon Fibroblasts

(2012) Juan A. Giménez-Bastida et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ellagitannin metabolites, urolithin A glucuronide and its aglycone urolithin A, ameliorate TNF-α-induced inflammation and associated molecular markers in human aortic endothelial cells

(2012) Juan A. Giménez-Bastida et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Bioavailability of the Glucuronide and Sulfate Conjugates of Genistein and Daidzein in Breast Cancer Resistance Protein 1 Knockout Mice

(2011) A. I. Alvarez et al.   DRUG METABOLISM AND DISPOSITION

Urolithins, ellagitannin metabolites produced by colon microbiota, inhibit Quorum Sensing in Yersinia enterocolitica: Phenotypic response and associated molecular changes

(2011) J.A. Giménez-Bastida et al.   FOOD CHEMISTRY

Strawberry Processing Does Not Affect the Production and Urinary Excretion of Urolithins, Ellagic Acid Metabolites, in Humans

(2011) Pilar Truchado et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

UV and MS Identification of Urolithins and Nasutins, the Bioavailable Metabolites of Ellagitannins and Ellagic Acid in Different Mammals

(2011) Rocío González-Barrio et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antiglycative and neuroprotective activity of colon-derived polyphenol catabolites

(2011) Elena Verzelloni et al.   MOLECULAR NUTRITION & FOOD RESEARCH

NF-κB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts

(2010) Antonio González-Sarrías et al.   BRITISH JOURNAL OF NUTRITION

Effects of Cell Differentiation and Assay Conditions on the UDP-Glucuronosyltransferase Activity in Caco-2 Cells

(2010) H. Zhang et al.   DRUG METABOLISM AND DISPOSITION

Colon Cancer Chemopreventive Activities of Pomegranate Ellagitannins and Urolithins

(2010) Sashi G. Kasimsetty et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria

(2010) Mario Dell'Agli et al.   MALARIA JOURNAL

Ellagitannins, ellagic acid and vascular health

(2010) Mar Larrosa et al.   MOLECULAR ASPECTS OF MEDICINE

Molecular mechanisms for chemoprevention of colorectal cancer by natural dietary compounds

(2010) Min-Hsiung Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression

(2009) J. Sugatani et al.   DRUG METABOLISM AND DISPOSITION

DissimilarIn VitroandIn VivoEffects of Ellagic Acid and Its Microbiota-Derived Metabolites, Urolithins, on the Cytochrome P450 1A1

(2009) Antonio González-Sarrías et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effects of Fruit Ellagitannin Extracts, Ellagic Acid, and Their Colonic Metabolite, Urolithin A, on Wnt Signaling†

(2009) Meenakshi Sharma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism☆

(2009) Mar Larrosa et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gene expression, cell cycle arrest and MAPK signalling regulation in Caco-2 cells exposed to ellagic acid and its metabolites, urolithins

(2009) Antonio González-Sarrías et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Occurrence of urolithins, gut microbiota ellagic acid metabolites and proliferation markers expression response in the human prostate gland upon consumption of walnuts and pomegranate juice

(2009) Antonio González-Sarrías et al.   MOLECULAR NUTRITION & FOOD RESEARCH