Article
Biochemistry & Molecular Biology
Salah Gariballa, Ghada S. M. Al-Bluwi, Javed Yasin
Summary: A study on 277 healthy individuals in the United Arab Emirates found an association between vitamin D receptor gene polymorphisms and vitamin D levels. However, this association became non-significant after adjusting for clinical parameters that influence vitamin D levels. Additionally, no association was found between obesity and related pathologies and the vitamin D receptor gene polymorphisms.
Article
Nutrition & Dietetics
Dahyun Park, Juhee Lee, Clara Yongjoo Park, Min-Jeong Shin
Summary: This study found that low levels of vitamin D (<20 ng/mL) were associated with a higher risk of mortality in Korean adults, especially in men and those with hypertension, suggesting an impact of vitamin D on mortality risk.
Article
Nutrition & Dietetics
Shuting Si, Minjia Mo, Haoyue Cheng, Zhicheng Peng, Xialidan Alifu, Haibo Zhou, Peihan Chi, Yan Zhuang, Yunxian Yu
Summary: The study identified individual and interactive associations between VitD deficiency during pregnancy and SNPs in the genes of the VitD metabolic pathway, which are related to blood pressure and the development of HDP.
Article
Nutrition & Dietetics
Rajiv Erasmus, Setjie Maepa, Ian Machingura, Saarah Davids, Shanel Raghubeer, Tandi Matsha
Summary: This study investigated the association between 25(OH) vitamin D, vitamin D-binding proteins, and vitamin D receptor (VDR) polymorphisms in a South African population. The results showed a high prevalence of vitamin D deficiency/insufficiency in this population, with decreased vitamin D levels observed in hyperglycaemic individuals. These findings can contribute to further research on the diagnosis and treatment of hyperglycaemia.
Article
Obstetrics & Gynecology
A. Subramanian, A. Z. Steiner, C. R. Weinberg, G. L. Doss, A. M. Z. Jukic
Summary: The study found no association between preconception vitamin D levels and the risk of miscarriage, indicating that there is no significant correlation between the two factors in a population of women conceiving naturally.
HUMAN REPRODUCTION
(2022)
Article
Biochemistry & Molecular Biology
Pollyanna Patriota, Serge Rezzi, Idris Guessous, Pedro Marques-Vidal
Summary: This study conducted in Switzerland assessed the association between 25-hydroxyvitamin D and long-term weight change. The findings suggest a limited correlation between genetically determined vitamin D levels and weight gain.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nutrition & Dietetics
Pollyanna Patriota, Serge Rezzi, Idris Guessous, Pedro Marques-Vidal
Summary: This population-based prospective cohort study found no association between vitamin D levels and changes in weight and waist circumference at 5- and 10-year follow-up.
Review
Cell Biology
Cennikon Pakpahan, Citrawati Dyah Kencono Wungu, Agustinus Agustinus, Darmadi Darmadi
Summary: This study found a correlation between the BsmI and FokI polymorphisms of the Vitamin D receptor gene and decreased bone density in men.
AGEING RESEARCH REVIEWS
(2022)
Article
Nutrition & Dietetics
Sepideh Zununi Vahed, Elham Ahmadian, Peyman Foroughi, Soroush Mostafavi, Henning Madry, Mohammadreza Ardalan, Magali Cucchiarini
Summary: The study revealed a significant association between VDR and VDBP gene polymorphisms with renal allograft rejection and viral infection, showing differences in G allele frequencies among different groups.
Review
Nutrition & Dietetics
Ricardo Usategui-Martin, Daniel-Antonio De Luis-Roman, Jose Maria Fernandez-Gomez, Marta Ruiz-Mambrilla, Jose-Luis Perez-Castrillon
Summary: This study evaluated the impact of polymorphisms in the vitamin D receptor gene on the response to vitamin D supplementation through a systematic review and meta-analysis. The results suggest that the TaqI and FokI polymorphisms may play a role in modulating the response to vitamin D supplementation.
Article
Nutrition & Dietetics
Valentina Aristarco, Harriet Johansson, Sara Gandini, Debora Macis, Cristina Zanzottera, Gianluca Tolva, Irene Feroce, Chiara Accornero, Bernardo Bonanni, Aliana Guerrieri-Gonzaga, Davide Serrano
Summary: This study found that SNPs of VDR and GC genes may influence breast cancer recurrence and survival in patients, particularly with major alleles of BsmI and TaqI showing lower risk of relapse.
Article
Respiratory System
Bastyte Daina, Tamasauskiene Laura, Golubickaite Ieva, Ugenskiene Rasa, Sitkauskiene Brigita
Summary: This study aimed to examine the possible association between VDR and VDBP gene polymorphisms, 25(OH)D, blood eosinophil count, and total IgE level in asthma patients. The findings revealed that the allele G of rs11168293 of VDR was more common in asthma patients with vitamin D deficiency. Asthmatic subjects with the rs11168293 G allele had significantly higher blood eosinophil count. Additionally, subjects with allergic asthma carrying the allele A of rs7041 on the VDBP gene had significantly higher IgE levels.
BMC PULMONARY MEDICINE
(2023)
Article
Nutrition & Dietetics
Weronika Galus, Tomasz Chmiela, Anna Walawska-Hrycek, Ewa Krzystanek
Summary: Current data highlight the importance of vitamin D in boosting the anti-inflammatory response, especially in patients with multiple sclerosis. While vitamin D deficiency is a known risk factor for developing multiple sclerosis, the benefits of vitamin D supplementation in this disease remain inconclusive. However, maintaining optimal or higher levels of vitamin D throughout the observation period was associated with a lower number of new lesions in patients with multiple sclerosis, suggesting the potential implementation and improvement of vitamin D in these patients.
Article
Public, Environmental & Occupational Health
Akiko Nanri, Tetsuya Mizoue, Atsushi Goto, Mitsuhiko Noda, Norie Sawada, Shoichiro Tsugane
Summary: This study found inconsistent associations between vitamin D intake and all-cause mortality as well as cause-specific mortality. Among Japanese adults, higher vitamin D intake was associated with a lower risk of all-cause mortality, particularly in individuals with low sunlight exposure. Higher intake of vitamin D was also linked to reduced mortality risk for individuals with hypertension and higher calcium intake.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Nutrition & Dietetics
Adriana J. van Ballegooijen, Joline W. J. Beulens, Lyanne M. Kieneker, Martin H. de Borst, Ron T. Gansevoort, Ido P. Kema, Leon J. Schurgers, Marc G. Vervloet, Stephan J. L. Bakker
Summary: Combined low vitamin D and K status are associated with increased all-cause mortality risk and possibly with cardiovascular mortality and cardiovascular events compared with adequate vitamin D and K status.
EUROPEAN JOURNAL OF NUTRITION
(2021)