Article
Radiology, Nuclear Medicine & Medical Imaging
Samuli Arvola, Marko Seppanen, Simona Malaspina, Sorjo Matzke, Juho Raiko, Kirsi L. Timonen, Otto Ettala, Ivan Jambor, Mikael Anttinen, Anna Kuisma, Eliisa Loyttyniemi, Peter J. Bostrom, Antti Sohlberg, Tommi Noponen
Summary: This study compared reprojected bone SPECT/CT (RBS) and planar bone scintigraphy (BS) in the detection of bone metastases in breast and prostate cancer patients. The results showed that RBS had higher sensitivity and did not require additional planar BS.
NUCLEAR MEDICINE COMMUNICATIONS
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Wei Liu, Xiao-Zuo Zheng, Zi-Qian Dong, Jian-Min Huang, Peng Xie
Summary: A 62-year-old man presented with a solitary scapular metastasis from prostate adenocarcinoma, which was detected by a bone scan. The intense activity in the coracoid process of the left scapula was confirmed as metastasis from prostate adenocarcinoma using subsequent pathological results.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Chemistry, Physical
Ew-Jun Chen, Teik Hin Tan, Ming Tsuey Chew
Summary: The study found that using xSPECT/CT Bone or standard OSEM SPECT/CT algorithm in prostate cancer patients with high PSA levels can improve the diagnostic accuracy of bone scans, particularly in delineating areas of bone metastasis.
RADIATION PHYSICS AND CHEMISTRY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Kenichi Tanaka, Takashi Norikane, Katsuya Mitamura, Yuka Yamamoto, Yukito Maeda, Kengo Fujimoto, Yasukage Takami, Mariko Ishimura, Hanae Arai-Okuda, Yoichiro Tohi, Nobuyuki Kudomi, Mikio Sugimoto, Yoshihiro Nishiyama
Summary: This study aimed to investigate the correlation between standardized uptake value (SUV) and volume-based parameters measured by quantitative SPECT/CT and PET/CT in the assessment of bone metastases in patients with prostate cancer. The results showed a strong correlation between SPECT/CT and PET/CT, with the SUV and volume-based parameters being significantly higher for metastatic lesions compared to benign lesions.
Review
Medicine, General & Internal
Wietske I. Luining, Dennie Meijer, Max R. Dahele, Andre N. Vis, Daniela E. Oprea-Lager
Summary: Accurate staging and treatment strategy are crucial for prognosis in prostate cancer. Traditional imaging techniques like CT and bone scintigraphy have limitations in sensitivity and specificity compared to modern nuclear imaging methods using novel radiotracers with PET/CT technology, which outperform conventional imaging in detecting PCa.
Article
Medicine, General & Internal
Cecile Cuvilliers, Xavier Palard-Novello, Clemence Pontoizeau, Pierre Meneret, Anne Devillers, Florence Le Jeune, Antoine Girard
Summary: Adding bloodpool SPECT/CT to standard three-phase bone scintigraphy significantly improved diagnostic accuracy for lower extremity pain, particularly in identifying tendonitis. This additional imaging modality increased confidence in diagnostic conclusions without impacting inter-reader agreement.
FRONTIERS IN MEDICINE
(2021)
Review
Medicine, General & Internal
Jeremy McGale, Sakshi Khurana, Alice Huang, Tina Roa, Randy Yeh, Dorsa Shirini, Parth Doshi, Abanoub Nakhla, Maria Bebawy, David Khalil, Andrew Lotfalla, Hayley Higgins, Amit Gulati, Antoine Girard, Francois-Clement Bidard, Laurence Champion, Phuong Duong, Laurent Dercle, Romain-David Seban
Summary: HER2-positive breast cancer, characterized by amplification of the HER2 gene, is associated with aggressive tumor growth, increased metastatic risk, and poorer prognosis compared to other subtypes. HER2 expression is a crucial tumor feature for breast cancer diagnosis and treatment. Advancements in HER2 in vivo imaging techniques like PET and SPECT may enhance the role of HER2 status in guiding breast cancer management, enabling determination of tumor size, location, and evaluation of treatment effectiveness. This review explores the current and future role of HER2 imaging in personalized care for breast cancer patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Mirela Gherghe, Mario-Demian Mutuleanu, Adina Elena Stanciu, Ionela Irimescu, Alexandra Lazar, Xenia Bacinschi, Rodica Maricela Anghel
Summary: Breast cancer patients often develop metastatic bone lesions, and using SPECT-CT quantitative analysis can help differentiate between these lesions and degenerative bone disease, improving diagnostic accuracy.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Patrick Martineau, Matthieu Pelletier-Galarneau
Summary: Haglund syndrome, consisting of Haglund's deformity, retrocalcaneal bursitis, and achilles tendinopathy, is a common cause of hind foot pain in adults. Diagnosis using planar scintigraphy can be challenging, but SPECT/CT can play a key role in its diagnosis.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ricarda Hinzpeter, Livia Baumann, Roman Guggenberger, Martin Huellner, Hatem Alkadhi, Bettina Baessler
Summary: This study successfully differentiated bone metastases not visible on CT but detected by (68) Ga-PSMA PET imaging using radiomics analysis, with a classification accuracy of 0.90, high sensitivity and specificity for bone metastases.
EUROPEAN RADIOLOGY
(2022)
Editorial Material
Medicine, General & Internal
Marie-Claude Eberle, Cyril Fersing, Sophie Guillemard, Diana Ilonca, Severine Guiu, Emmanuel Deshayes
Summary: A 48-year-old woman with breast cancer underwent a bone scan and two hot spots were found in the left lung. CT slices showed no abnormalities and other possible causes were ruled out. Radiotracer microembolism seems to be the most likely hypothesis in this case.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Patrick Martineau, Matthieu Pelletier-Galarneau
Summary: Sinus tarsi syndrome is a common cause of hindfoot pain in adults, with diagnosis on planar bone scintigraphy being challenging. This study presents 3 cases of sinus tarsi syndrome, reviews the spectrum of imaging findings associated with the syndrome, and emphasizes the key role that SPECT/CT can play in its diagnosis.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Samuli Arvola, Marko Seppanen, Kirsi L. Timonen, Pentti Rautio, Otto Ettala, Mikael Anttinen, Peter J. Bostrom, Tommi Noponen
Summary: Changes in acquisition time, energy window width, and matrix size of Tc-99m-HMDP SPECT/CT can affect image quality, but without compromising diagnostic performance. A reduction in acquisition time to 38 min, narrowing of the energy window to 8%, and increasing the matrix size to 256 x 256 can still maintain acceptable qualitative image quality.
Article
Radiology, Nuclear Medicine & Medical Imaging
Helmut Dittmann, Sabine Kaltenbach, Matthias Weissinger, Francesco Fiz, Peter Martus, Maren Pritzkow, Juergen Kupferschlaeger, Christian la Fougere
Summary: This study aimed to quantify the uptake of Tc-99m-DPD in bone metastases of prostate cancer patients before Ra-223 treatment and compare it with treatment feasibility and overall survival. Results showed that patients with higher bone uptake were more likely unable to complete Ra-223 treatment and had lower survival rates.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Article
Oncology
Mirela Gherghe, Mario-Demian Mutuleanu, Adina Elena Stanciu, Ionela Irimescu, Alexandra Maria Lazar, Radu Valeriu Toma, Oana Gabriela Trifanescu, Rodica Maricela Anghel
Summary: By quantitatively interpreting SPECT-CT images, we can better demonstrate changes in radiotracer uptake between baseline and follow-up scans in breast cancer patients with metastatic bone disease, compared to qualitative assessment. This method provides a standardized and robust approach for patient follow-up evaluation, which is particularly important for research purposes.
Letter
Radiology, Nuclear Medicine & Medical Imaging
Kambiz Rahbar, Hojjat Ahmadzadehfar, Martin Boegemann
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Milka Marinova, Martin Muecke, Lukas Mahlberg, Markus Essler, Henning Cuhls, Lukas Radbruch, Rupert Conrad, Hojjat Ahmadzadehfar
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2018)
Article
Oncology
Yuri Tolkach, Heidrun Gevensleben, Ralph Bundschuh, Aydan Koyun, Daniela Huber, Christina Kehrer, Thomas Hecking, Mignon-Denise Keyver-Paik, Christina Kaiser, Hojjat Ahmadzadehfar, Markus Essler, Walther Kuhn, Glen Kristiansen
BREAST CANCER RESEARCH AND TREATMENT
(2018)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Kambiz Rahbar, Matthias Weckesser, Hojjat Ahmadzadehfar, Michael Schaefers, Lars Stegger, Martin Boegemann
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2018)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Hojjat Ahmadzadehfar, Markus Essler
JOURNAL OF NUCLEAR MEDICINE
(2018)
Article
Oncology
Johannes Linxweiler, Matthias Saar, Zaid Al-Kailani, Martin Janssen, Samer Ezziddin, Michael Stoeckle, Stefan Siemer, Carsten-Henning Ohlmann
SURGICAL ONCOLOGY-OXFORD
(2018)
Article
Gastroenterology & Hepatology
Anja Rinke, Bertram Wiedenmann, Christoph Auernhammer, Peter Bartenstein, Detlef K. Bartsch, Nehara Begum, Siegbert Faiss, Christian Fottner, Bernhard Gebauer, Peter Goretzki, Petra Lynen Jansen, Gabriele Poepperl, Hans Scheruebl, Matthias M. Weber, Thomas Mathias Gress, Marianne Pavel, Jorg Albert, Heiko Alfke, Holger Amthauer, Martin Anlauf, Rudolf Arnold, Richard Baum, Timm Denecke, Samer Ezziddin, Volker Fendrich, Stefan Gniffke, Alexander Haug, Dieter Hoersch, Thomas Kegel, Wolfram Trudo Knoefel, Thomas Knoesel, Clemens Kratochwil, Harald Lahner, Florian Lordick, Markus Luster, Andreas Mahnken, Katharina Mellar, Heiner Moenig, Thomas J. Musholt, Monika Nothacker, Ulrich-Frank Pape, Andreas Pascher, Thorsten Poeppel, Vikas Prasad, Andreas Probst, Klemens Scheidhauer, Dominik Schneider, Matthias Schott, Joerg Schrader, Thomas Seufferlein, Bence Sipos, Christine Spitzweg, Thomas Steinmueller, Christoph Trumm, Christine Wurst, Niels Zorger
ZEITSCHRIFT FUR GASTROENTEROLOGIE
(2018)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Hojjat Ahmadzadehfar, Markus Essler
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Martin Ries, Fadi Khreish, Christian Veith, Joachim von den Hoff, Samer Ezziddin
CLINICAL NUCLEAR MEDICINE
(2019)
Article
Environmental Sciences
Clemens Scholl, Ralph A. Bundschuh, Stefan Hirzebruch, Tim Glanert, Xiao Wei, Stefan Kuerpig, Roland Roedel, Markus Essler, Lena Thomas, Hojjat Ahmadzadehfar
JOURNAL OF RADIOLOGICAL PROTECTION
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Milka Marinova, Martin Muecke, Felix Fischer, Markus Essler, Henning Cuhls, Lukas Radbruch, Shiwa Ghaei, Rupert Conrad, Hojjat Ahmadzadehfar
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2019)
Review
Pharmacology & Pharmacy
Narges Jokar, Majid Assadi, Anna Yordanova, Hojjat Ahmadzadehfar
CURRENT PHARMACEUTICAL DESIGN
(2020)
Review
Pharmacology & Pharmacy
Majid Assadi, Narges Jokar, Mojtaba Ghasemi, Iraj Nabipour, Ali Gholamrezanezhad, Hojjat Ahmadzadehfar
CURRENT PHARMACEUTICAL DESIGN
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hojjat Ahmadzadehfar, Ralf Matern, Richard P. Baum, Robert Seifert, Katharina Kessel, Martin Boegemann, Clemens Kratochwil, Hendrik Rathke, Harun Ilhan, Hanna Svirydenka, Mike Sathekge, Levent Kabasakal, Anna Yordanova, Francisco Osvaldo Garcia-Perez, Kalevi Kairemo, Masha Maharaj, Diana Paez, Irene Virgolini, Kambiz Rahbar
Summary: The extent of bone metastases negatively correlated with overall survival after RLT, but showed no significant correlation with PSA response rate. Prior therapy with Ra-223 may have a positive impact on overall survival.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Majid Assadi, Seyed Javad Rekabpour, Abdullatif Amini, Habibollah Dadgar, Reza Nemati, Ali Gholamrezanezhad, Iraj Nabipour, Esmail Jafari, Hojjat Ahmadzadehfar
MOLECULAR IMAGING AND RADIONUCLIDE THERAPY
(2021)