Do proconvulsants modify or halt epileptogenesis? Pentylenetetrazole is ineffective in two rat models of temporal lobe epilepsy

Blood-brain barrier dysfunction, status epilepticus, seizures, and epilepsy: A puzzle of a chicken and egg?

(2011) Alon Friedman   EPILEPSIA

Mechanisms of epileptogenesis and potential treatment targets

(2011) Asla Pitkänen et al.   LANCET NEUROLOGY

The effect of the cannabinoid-receptor antagonist, SR141716, on the early stage of kainate-induced epileptogenesis in the adult rat

(2010) F. Edward Dudek et al.   EPILEPSIA

Therapeutic approaches to epileptogenesis-Hope on the horizon

(2010) Asla Pitkänen   EPILEPSIA

Post-traumatic seizure susceptibility is attenuated by hypothermia therapy

(2010) Coleen M. Atkins et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Disease-Modifying Effects of Phenobarbital and the NKCC1 Inhibitor Bumetanide in the Pilocarpine Model of Temporal Lobe Epilepsy

(2010) C. Brandt et al.   JOURNAL OF NEUROSCIENCE

Enhanced susceptibility to the GABA antagonist pentylenetetrazole during the latent period following a pilocarpine-induced status epilepticus in rats

(2010) Marta Rattka et al.   NEUROPHARMACOLOGY

Prevention or Modification of Epileptogenesis after Brain Insults: Experimental Approaches and Translational Research

(2010) W. Loscher et al.   PHARMACOLOGICAL REVIEWS

The multifaceted role of inhibition in epilepsy: seizure-genesis through excessive GABAergic inhibition in autosomal dominant nocturnal frontal lobe epilepsy

(2009) Edward O Mann et al.   CURRENT OPINION IN NEUROLOGY

Posttraumatic epilepsy: The challenge of translating discoveries in the laboratory to pathways to a cure

(2009) Marc A. Dichter   EPILEPSIA

Pursuing paradoxical proconvulsant prophylaxis for epileptogenesis

(2009) Caren Armstrong et al.   EPILEPSIA

From traumatic brain injury to posttraumatic epilepsy: What animal models tell us about the process and treatment options

(2009) Asla Pitkänen et al.   EPILEPSIA

Is a first acute symptomatic seizure epilepsy? Mortality and risk for recurrent seizure

(2009) Dale C. Hesdorffer et al.   EPILEPSIA

Preventing and treating posttraumatic seizures: The human experience

(2009) Nancy R. Temkin   EPILEPSIA

Recommendation for a definition of acute symptomatic seizure

(2009) Ettore Beghi et al.   EPILEPSIA

Curing epilepsy: Progress and future directions

(2009) Margaret P. Jacobs et al.   EPILEPSY & BEHAVIOR

Single application of a CB1 receptor antagonist rapidly following head injury prevents long-term hyperexcitability in a rat model

(2009) Julio Echegoyen et al.   EPILEPSY RESEARCH

Preclinical assessment of proconvulsant drug activity and its relevance for predicting adverse events in humans

(2009) Wolfgang Löscher   EUROPEAN JOURNAL OF PHARMACOLOGY

The Cause of the Imbalance in the Neuronal Network Leading to Seizure Activity Can Be Predicted by the Electrographic Pattern of the Seizure Onset

(2009) A. Bragin et al.   JOURNAL OF NEUROSCIENCE

Kindling as a model of temporal lobe epilepsy induces bilateral changes in spontaneous striatal activity

(2009) Saskia Kücker et al.   NEUROBIOLOGY OF DISEASE

Cation-Chloride Cotransporters and Neuronal Function

(2009) Peter Blaesse et al.   NEURON

Commentary: A skeptical view of experimental gene therapy to block epileptogenesis

(2009) F. Edward Dudek   Neurotherapeutics

Seizures in the intrahippocampal kainic acid epilepsy model: characterization using long-term video-EEG monitoring in the rat

(2008) R. Raedt et al.   ACTA NEUROLOGICA SCANDINAVICA

Molecular and cellular basis of epileptogenesis in symptomatic epilepsy

(2008) Asla Pitkänen et al.   EPILEPSY & BEHAVIOR

Traumatic brain injury during development reduces minimal clonic seizure thresholds at maturity

(2008) Kimberly D. Statler et al.   EPILEPSY RESEARCH

Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus

(2008) Jens P. Bankstahl et al.   EPILEPSY RESEARCH