Article
Multidisciplinary Sciences
Kyung-min An, Jeong Hyun Shim, Hyukchan Kwon, Yong-Ho Lee, Kwon-Kyu Yu, Moonyoung Kwon, WooYoung Chun, Tetsu Hirosawa, Chiaki Hasegawa, Sumie Iwasaki, Mitsuru Kikuchi, Kiwoong Kim
Summary: Magnetoencephalography (MEG) is a noninvasive functional neuroimaging technique that detects brain magnetic field. Traditional MEG uses superconducting quantum interference devices (SQUIDs), while miniature optically pumped magnetometers (OPMs) have recently been developed as an alternative. The study suggests that OPM sensors have comparable performance to conventional SQUID-MEG sensors, showing the feasibility of using OPM sensors for functional neuroimaging and brain-computer interface applications.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
Shunsuke Sugiyama, Tomoya Taniguchi, Tomoaki Kinukawa, Nobuyuki Takeuchi, Kazutaka Ohi, Toshiki Shioiri, Makoto Nishihara, Koji Inui
Summary: This study used magnetoencephalography to investigate the effects of 40 Hz auditory stimulation on brain activity and revealed the specific neural circuit activation mechanism underlying the 40 Hz ASSR. These findings are of great importance for understanding oscillatory abnormalities in neuropsychiatric disorders such as schizophrenia.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Vardan Arutiunian, Giorgio Arcara, Irina Buyanova, Elizaveta Davydova, Darya Pereverzeva, Alexander Sorokin, Svetlana Tyushkevich, Uliana Mamokhina, Kamilla Danilina, Olga Dragoy
Summary: Language impairment is common in children with Autism Spectrum Disorder (ASD), and the neural mechanisms behind it are not well understood. This study investigates the relationship between a specific auditory response (40 Hz ASSR) and language abilities in children with ASD using MEG and individual brain models. The results show reduced 40 Hz ASSR in the right auditory cortex of children with ASD and an association between 40 Hz ASSR in the left auditory cortex and language comprehension.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2023)
Article
Neurosciences
Vardan Arutiunian, Giorgio Arcara, Irina Buyanova, Militina Gomozova, Olga Dragoy
Summary: Recent studies have found that gamma-band oscillations and transient evoked potentials in children may change with age, potentially related to the maturation of the GABAergic neurotransmission system and the balance between excitation and inhibition in neural circuits. In this study, using magnetoencephalography (MEG), researchers investigated the relationship between 40 Hz auditory steady-state gamma response (ASSR) and sustained event-related field (ERF) response to the same periodic stimuli in a group of 30 typically developing children aged 7 to 12 years. The results showed a strong association between the strength of 40 Hz ASSR and the amplitude of ERF, with age-related changes observed in both responses.
HUMAN BRAIN MAPPING
(2022)
Article
Multidisciplinary Sciences
Hisse Arnts, Prejaas Tewarie, Willemijn S. van Erp, Berno U. Overbeek, Cornelis J. Stam, Jan C. M. Lavrijsen, Jan Booij, William P. Vandertop, Rick Schuurman, Arjan Hillebrand, Pepijn van den Munckhof
Summary: This study investigated the effects of DBS on oscillatory activity and functional connectivity in a patient with prolonged minimally conscious state. The results showed that a lower frequency and larger volume of tissue activation in DBS were associated with increased functional connectivity and neural variability throughout the brain. However, the patient's neurophysiological markers and objective measures of consciousness remained lower than in healthy controls.
SCIENTIFIC REPORTS
(2022)
Article
Mechanics
Xiaoyan Yang, Ye Li
Summary: Based on the recent study by Yang et al., this research investigates two primary waves traveling with an arbitrary included angle by solving the water-wave equations as a nonlinear boundary-value problem. The homotopy analysis method is used to solve the problem of small denominators and singularity. It is found that as the acute angle between the two primary wave components becomes smaller, the wave energy slowly shifts from the primary wave components to the high-order wave components, and the increase in wave amplitude strengthens this energy transfer.
Article
Psychiatry
Tetsu Hirosawa, Daiki Soma, Yoshiaki Miyagishi, Naoki Furutani, Yuko Yoshimura, Masafumi Kameya, Yohei Yamaguchi, Ken Yaoi, Masuhiko Sano, Koji Kitamura, Tetsuya Takahashi, Mitsuru Kikuchi
Summary: This study used graph theory to evaluate the effect of tDCS on the brain network of 40 Hz ASSR and found that tDCS can significantly improve the functional integration of the whole-brain network of 40 Hz ASSR. In addition, the study also found that individuals with lower initial functional integration showed a more pronounced effect after receiving tDCS.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Clinical Neurology
Oskar Hougaard Jefsen, Yury Shtyrov, Kit Melissa Larsen, Martin J. Dietz
Summary: This study explored the evidence of 40-Hz ASSR deficits in patients with bipolar disorder, and found consistent reductions in 40-Hz ASSR evoked power and inter-trial phase coherence compared with healthy controls. Further large-scale studies are needed to link 40-Hz ASSR deficits to clinical features and developmental trajectories.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Audiology & Speech-Language Pathology
Sho Otsuka, Shigeto Furukawa
Summary: Research shows that AM-to-PM conversion occurs in the human cochlea, and listeners can use PM information to process AM of sounds. OAE experiments support this phenomenon and reveal a correlation between PM and AM in auditory perception.
Article
Physics, Multidisciplinary
Mengxin Chen, Qianqian Zheng
Summary: In this paper, the authors investigate the pattern dynamics of a population model with chemotaxis. They study the existence of solutions and the global stability of the coexistence equilibrium. The authors also explore the steady state bifurcation induced by chemotaxis in the spatiotemporal model, with multiple thresholds depending on different assumptions. They provide an amplitude equation to determine the direction of the steady state bifurcation and validate the theoretical analysis with numerical results.
PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS
(2023)
Article
Neurosciences
Shauni Van Herck, Maria Economou, Femke Vanden Bempt, Pol Ghesquiere, Maaike Vandermosten, Jan Wouters
Summary: Neural processing of the speech envelope is important for speech perception and comprehension. Pulsatile amplitude-modulated stimuli are suggested to have increased potential for uncovering the neural mechanisms behind developmental disorders such as dyslexia. A longitudinal study with typically reading children showed that pulsatile stimuli significantly enhance neural synchronization at syllable rate and elicit a different hemispheric specialization. Using pulsatile stimuli can greatly improve EEG data acquisition efficiency in research on younger children and developmental reading research.
Article
Neurosciences
Tao Wang, Yuner Chen, Qiuyang Fu, Xiaodan Tan
Summary: This study validated the existence of transient responses from conventional auditory steady-state responses (ASSRs), and found stable transient responses across different stimulus rates, indicating the superposition hypothesis is applicable to the generation of AM-ASSRs. The new transient responses are characterized by specific peak-trough pairs within 40 ms, offering insights into the constitution of AM-ASSRs and potential applications in clinical settings.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2021)
Review
Psychiatry
Shunsuke Sugiyama, Kazutaka Ohi, Ayumi Kuramitsu, Kentaro Takai, Yukimasa Muto, Tomoya Taniguchi, Tomoaki Kinukawa, Nobuyuki Takeuchi, Eishi Motomura, Makoto Nishihara, Toshiki Shioiri, Koji Inui
Summary: Sensory processing deficits are present in several psychiatric disorders, with ASSR abnormalities observed in patients with schizophrenia, bipolar disorder, and autism spectrum disorder. The ASSR amplitude is suppressed within the gamma band among these patients, showing an imbalance between GABAergic and NMDA receptor-mediated neurotransmission. Commonalities in ASSR deficits at gamma frequencies suggest shared pathophysiological mechanisms across these disorders.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Multidisciplinary Sciences
Jaime Caballero-Insaurriaga, Jose A. Pineda-Pardo, Ignacio Obeso, Antonio Oliviero, Guglielmo Foffani
Summary: This study combined transcranial static magnetic field stimulation (tSMS) with resting-state functional MRI (fMRI) to investigate corticostriatal activity and found that tSMS can noninvasively modulate corticostriatal activity in humans. The results showed that the supplementary motor area (SMA) is the main region with functional connectivity to the striatum, and tSMS can modulate local activity in the SMA, adjacent sensorimotor cortex, and motor striatum. The findings also indicated that the tSMS-induced modulation of striatal activity can be primarily explained by a change in the shared activity between the modulated motor cortical areas and the motor striatum. These results suggest that corticostriatal activity can be targeted, monitored, and modulated noninvasively in humans.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Neurosciences
Yusuke Takeda, Nobuo Hiroe, Okito Yamashita
Summary: Repetitive propagating activities in the resting-state brain reflect past experiences and integrate information distributed over the entire brain, such as visual and motor information. These activities exhibit multiple resting-state networks in different frequency components, suggesting a process of integrating distributed information.
Article
Audiology & Speech-Language Pathology
Ghada BinKhamis, Agnes Leger, Steven L. Bell, Garreth Prendergast, Martin O'Driscoll, Karolina Kluk
Editorial Material
Audiology & Speech-Language Pathology
Kevin J. Munro, Garreth Prendergast
INTERNATIONAL JOURNAL OF AUDIOLOGY
(2019)
Article
Audiology & Speech-Language Pathology
Hannah Guest, Kevin J. Munro, Garreth Prendergast, Christopher J. Plack
Article
Audiology & Speech-Language Pathology
Arwa AlJasser, Kai Uus, Garreth Prendergast, Christopher J. Plack
Article
Acoustics
Michael A. Stone, Garreth Prendergast, Shanelle Canavan
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2020)
Article
Neurosciences
Rebecca S. Dewey, Susan T. Francis, Hannah Guest, Garreth Prendergast, Rebecca E. Millman, Christopher J. Plack, Deborah A. Hall
Article
Audiology & Speech-Language Pathology
Samuel Couth, Garreth Prendergast, Hannah Guest, Kevin J. Munro, David R. Moore, Christopher J. Plack, Jane Ginsborg, Piers Dawes
Article
Neurosciences
Andrew J. Quinn, Gary G. R. Green, Mark Hymers
Summary: This study introduces a data-driven modal decomposition method for identifying the characteristics of oscillatory networks, revealing significant variability in oscillation frequency and network structure among participants. It demonstrates that the transfer function can be rewritten in modal coordinates, allowing for individual analysis of oscillatory signals in terms of their spectral content, spatial distribution, and network structure.
Article
Geriatrics & Gerontology
Adnan M. Shehabi, Garreth Prendergast, Hannah Guest, Christopher J. Plack
Summary: Animal research shows that aging and excessive noise exposure can damage the auditory system and lead to auditory disorders. This study used an online approach to assess the effects of lifetime noise exposure and aging on speech perception, hearing ability, and tinnitus. The results indicate that older adults have poorer speech perception and a higher risk of tinnitus. Additionally, lifetime noise exposure may increase the risk of tinnitus and hyperacusis in young adults.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Audiology & Speech-Language Pathology
Adnan M. Shehabi, Garreth Prendergast, Hannah Guest, Christopher J. Plack
Summary: Noise exposure can damage the synapses connecting inner hair cells and auditory nerve fibers, leading to decreased temporal coding in peripheral auditory system. This study aimed to investigate the association between middle ear muscle reflex (MEMR) thresholds, as a proxy measure of cochlear synaptopathy (CS), and binaural intelligibility level difference (BILD), a measure of binaural temporal coding. The results showed no significant association between MEMR thresholds and DIN BILD. However, greater lifetime noise exposure tended to be associated with higher MEMR thresholds, larger DIN BILD values, and better antiphasic DIN thresholds. Overall, there was no evidence of CS impacting binaural temporal processing in young adults with normal hearing.
Letter
Audiology & Speech-Language Pathology
Garreth Prendergast, Aala Sindi, Kevin J. Munro
INTERNATIONAL JOURNAL OF AUDIOLOGY
(2023)
Article
Audiology & Speech-Language Pathology
Garreth Prendergast, Tanvi S. S. Sathe, Antje Heinrich, Kevin J. J. Munro
Summary: The clinical audiology test battery often uses simple sounds with questionable ecological value to the listener. This technical report reevaluates the validity of this approach using an automated, involuntary auditory response known as the acoustic reflex threshold (ART).
INTERNATIONAL JOURNAL OF AUDIOLOGY
(2023)
Article
Geriatrics & Gerontology
Ece Kocagoncu, Andrew Quinn, Azadeh Firouzian, Elisa Cooper, Andrea Greve, Roger Gunn, Gary Green, Mark W. Woolrich, Richard N. Henson, Simon Lovestone, James B. Rowe
NEUROBIOLOGY OF AGING
(2020)
Article
Audiology & Speech-Language Pathology
Hannah Guest, Kevin J. Munro, Samuel Couth, Rebecca E. Millman, Garreth Prendergast, Karolina Kluk, Carlyn Murray, Chris Plack
Article
Audiology & Speech-Language Pathology
Garreth Prendergast, Samuel Couth, Rebecca E. Millman, Hannah Guest, Karolina Kluk, Kevin J. Munro, Christopher J. Plack