期刊
EUROPEAN JOURNAL OF MEDICAL GENETICS
卷 51, 期 1, 页码 44-53出版社
ELSEVIER
DOI: 10.1016/j.ejmg.2007.10.002
关键词
automated pattern recognition; computer-assisted diagnosis; classification; dysmorphism; face
Digital image analysis of faces has been demonstrated to be effective in a small number of syndromes. In this paper we investigate several aspects that help bringing these methods closer to clinical application. First, we investigate the impact of increasing the number of syndromes from 10 to 14 as compared to an earlier study. Second, we include a side-view pose into the analysis and third, we scrutinize the effect of geometry information. Picture analysis uses a Gabor wavelet transform, standardization of landmark coordinates and subsequent statistical analysis. We can dernonstrate that classification accuracy drops from 76% for 10 syndromes to 70% for 14 syndromes for frontal images. Including side-views achieves an accuracy of 76% again. Geometry performs excellently with 85% for combined poses. Combination of wavelets and geometry for both poses increases accuracy to 93%. In conclusion, a larger number of syndromes can be handled effectively by means of image analysis. (c) 2007 Elsevier Masson SAS. All rights reserved.
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