Article
Chemistry, Multidisciplinary
Jun Takaya
Summary: Recent research has demonstrated the promising utility of transition metal complexes with M-E bonds stabilized by multidentate ligands, where E represents a main group metal or metalloid element. Main group metal and metalloid ligands provide unique electronic and steric environments to transition metals, leading to remarkable catalytic activity and product selectivity. This perspective highlights the potential of these compounds as a new class of supporting ligands for transition metal catalysts in synthetic chemistry.
Article
Chemistry, Multidisciplinary
Sebastian Koniarz, Kinga Szydelko, Michal J. Bialek, Karolina Hurej, Piotr J. Chmielewski
Summary: A family of transition metal complexes based on meso-aryl-2-aza-21-carbaporphyrin (N-confused porphyrin, NCP) derivatives were synthesized and characterized. The chirality of these complexes was demonstrated by enantiomeric separation and analysis. Preliminary catalytic study showed the activity of iridium(III) ortho-metallated complexes in the N-heterocyclization of primary amines with diols.
Article
Chemistry, Multidisciplinary
Maria Lago-Silva, Maria Magdalena Cid, Emilio Quinoa, Felix Freire
Summary: This article presents a new mechanism for helix inversion in polymers, which is achieved by activating/deactivating supramolecular interactions. The screw sense of the polymer is fixed by the spatial orientation of the substituents, but can be reversed through supramolecular interactions and external stimuli.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Physical
Chaoyan Ma, Can Li, Jiahui Bai, Junzhe Xiao, Yizhan Zhai, Yinlong Guo, Shengming Ma
Summary: In this study, a rhodium-catalyzed C-H functionalization-based intermolecular allylation of indoles with trisubstituted allenes has been developed. The synthetic process demonstrates excellent regioselectivity, Z-selectivity, high efficiency of chirality transfer, and a wide tolerance of reactive functional groups under mild conditions. Late-stage modification on complex bioactive or drug molecules has been achieved, along with various synthetic transformations. A reaction mechanism has been proposed based on mechanistic experiments and SAESI-MS studies.
Review
Chemistry, Multidisciplinary
Yang-Bo Chen, Ye-Nan Yang, Xuan-Zhu Huo, Long-Wu Ye, Bo Zhou
Summary: The catalytic enantioselective preparation of axially chiral molecules has become a topic of significant interest in recent decades due to their wide-ranging applications. While there are well-established synthetic approaches for six-membered axially chiral skeletons, methods for five-membered axially chiral compounds are relatively rare. Among these compounds, axially chiral arylpyrroles are particularly important and desirable. This review summarizes recent advances in the atroposelective preparation of arylpyrroles, focusing on the synthetic methods for each axially chiral framework, reaction mechanisms, and applications.
SCIENCE CHINA-CHEMISTRY
(2023)
Review
Chemistry, Inorganic & Nuclear
Pengcheng Gao, Michal Szostak
Summary: The catalytic addition of water to unsaturated C-C or C-N p bonds is an important and environmentally sustainable method for forming C-O bonds. Traditional acid-catalyzed hydration requires strong acids or toxic mercury salts, limiting its practical applications and posing safety and environmental concerns. Transition-metal-catalyzed hydration with NHC ligands has gained significant attention and has achieved major progress. This review provides a comprehensive overview of hydration reactions catalyzed by transition metal-NHC complexes and their applications in catalytic hydration.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Wenbo Dong, Yi Yang, Yonggang Xiang, Shengyao Wang, Pei Wang, Jianxiang Hu, Li Rao, Hao Chen
Summary: The newly designed dual nickel/photocatalysis 2D covalent organic framework (COF) has successfully overcome the difficulties of recycling photosensitizers or nickel complexes, efficiently converting aryl bromides to aryl alkyl ethers with good substrate compatibility and functional group tolerance.
Article
Chemistry, Inorganic & Nuclear
Jin Young Koo, Jongwon Oh, Gyeongeun Hyun, Hee Cheul Choi, Intek Song, Seok Min Yoon
Summary: A new oxo-bridged chromium-molybdenum heterometallic complex, O-CrMoHC, was synthesized by a solvothermal reaction. The complex exhibits anisotropic conductivity in single crystals, with higher electrical conductivity along the [01-1] direction compared to the [100] direction. This is the first report of anisotropic conductivity observed in a monomeric heterometallic complex single crystal.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Chuan Xiang Alvin Tan, Rui Li, Fuhao Zhang, Lei Dai, Nisar Ullah, Yixin Lu
Summary: A sequential phosphine-catalyzed asymmetric [3+2] annulation of aldimines has been developed, utilizing an oxidative central-to-axial chirality transfer strategy. This approach is operationally simple and allows for the rapid synthesis of highly enantioselective 2-arylpyrroles.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Applied
Xiang Zhang, Bo-Tao Chen, Peng Gao, Rui-Ping Song, Fang Fang, Dan-Dan Han, You-Dong Shao, Dao-Juan Cheng
Summary: An iron(III) triflate catalyzed Friedlander-type heteroannulation method has been developed for the synthesis of various quinoline-containing tertiary amides. The study also identified a stable axially chiral quinoline-4-carboxamide and attempted an enantioselective catalytic reaction.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Chemistry, Physical
Xuan Jiang, Wei Xiong, Shuang Deng, Fu-Dong Lu, Yue Jia, Qian Yang, Li-Yuan Xue, Xiaotian Qi, Jon A. Tunge, Liang-Qiu Lu, Wen-Jing Xiao
Summary: This article introduces a sustainable and economic alternative to palladium in asymmetric radical couplings using 3D metals. By combining asymmetric cobalt catalysis with organic photoredox catalysis and identifying an efficient chiral polydentate ligand, the authors successfully achieved visible-light-induced asymmetric radical couplings for the construction of axial chirality.
Review
Chemistry, Multidisciplinary
Yichen Wu, Peng Wang
Summary: Optically active organosilanes have been demonstrated to be versatile chiral reagents in synthetic chemistry. Monohydrosilanes, which bear a Si-H bond, are especially unique due to their facile transformations through stereospecific bond-formation reactions. In addition, they have also been used as chiral reagents for alcohol resolution, chiral auxiliaries, mechanistic probes, and potential optoelectronic materials.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Ziyong Li, Ying Chen, Chuang Wang, Guangyang Xu, Ying Shao, Xinhao Zhang, Shengbiao Tang, Jiangtao Sun
Summary: The atroposelective synthesis of biaryl atropisomers via asymmetric C(sp(2))-H bond insertion reaction of arenes under rhodium catalysis has been achieved, providing moderate to excellent yields with good enantiomeric ratios. Further investigation suggests that this type of axially biaryl scaffold may have promising potentials in developing novel chiral ligands.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Polymer Science
Thi Tran, Loi H. Do
Summary: This review article provides an overview of various methods for regulating the polymerization of olefins using transition metal complexes, including catalyst tuning through reaction engineering and introduction of external stimuli. The unique capabilities and limitations of different approaches are discussed, along with the potential impacts of externally regulated polymerization on applications and future research.
EUROPEAN POLYMER JOURNAL
(2021)
Review
Biochemistry & Molecular Biology
Sana Sikandar, Ameer Fawad Zahoor, Abdul Ghaffar, Muhammad Naveed Anjum, Razia Noreen, Ali Irfan, Bushra Munir, Katarzyna Kotwica-Mojzych, Mariusz Mojzych
Summary: Allenes are a unique class of unsaturated hydrocarbons with two carbon-carbon double bonds. They are highly reactive and exhibit significant axial chirality, making them important in asymmetric synthesis. This review discusses the different types of annulations using metal catalyzed cycloaddition reactions, and also highlights the synthetic applications of these reactions towards natural products.
