The amount of self-antigen determines the effector function of murine T cells escaping negative selection

CD4+ T Cells Recognizing a Single Self-Peptide Expressed by APCs Induce Spontaneous Autoimmune Arthritis

(2014) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

Clonal deletion and the fate of autoreactive thymocytes that survive negative selection

(2012) Leonid A Pobezinsky et al.   NATURE IMMUNOLOGY

CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire

(2012) J. Verhagen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-antigen presentation by mouse B cells results in regulatory T-cell induction rather than anergy or clonal deletion

(2011) S. Morlacchi et al.   BLOOD

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

(2011) A. V. Rubtsov et al.   BLOOD

Signaling in thymic selection

(2011) Nicholas RJ Gascoigne et al.   CURRENT OPINION IN IMMUNOLOGY

Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope

(2011) Carolin Daniel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo

(2010) Rachel A. Gottschalk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

(2010) Jung-Hyun Park et al.   NATURE IMMUNOLOGY

Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance

(2010) Maria Hinterberger et al.   NATURE IMMUNOLOGY

Thymocyte deletion can bias Treg formation toward low-abundance self-peptide

(2009) Cristina Cozzo Picca et al.   EUROPEAN JOURNAL OF IMMUNOLOGY