Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands

IL-9 is a Th17-derived cytokine that limits pathogenic activity in organ-specific autoimmune disease

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An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells

(2011) Sascha Rutz et al.   NATURE IMMUNOLOGY

The IL-17 pathway as a major therapeutic target in autoimmune diseases

(2010) Yan Hu et al.   Annals of the New York Academy of Sciences

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kynurenic Acid Is a Potent Endogenous Aryl Hydrocarbon Receptor Ligand that Synergistically Induces Interleukin-6 in the Presence of Inflammatory Signaling

(2010) Brett C. DiNatale et al.   TOXICOLOGICAL SCIENCES

Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis

(2009) J. Rodgers et al.   BRAIN

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

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