Epigenetic reprogramming of the RORC locus during in vitro expansion is a distinctive feature of human memory but not naïve Treg

Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA Methylation

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Isolation of intact genomic DNA from FOXP3-sorted human regulatory T cells for epigenetic analyses

(2010) Leo Hansmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

FoxP3+ROR t+ T Helper Intermediates Display Suppressive Function against Autoimmune Diabetes

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Epigenetic mechanisms of regulation of Foxp3 expression

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IL-17-producing human peripheral regulatory T cells retain suppressive function

(2009) G. Beriou et al.   BLOOD

IL-1β and IL-2 convert human Treg into TH17 cells

(2009) Florence Deknuydt et al.   CLINICAL IMMUNOLOGY

Plasticity of CD4+ FoxP3+ T cells

(2009) Xuyu Zhou et al.   CURRENT OPINION IN IMMUNOLOGY

Loss of FOXP3 expression in natural human CD4+CD25+regulatory T cells upon repetitivein vitrostimulation

(2009) Petra Hoffmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity

(2009) C. Schmidl et al.   GENOME RESEARCH

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+inducible regulatory T cells

(2009) Sven Klunker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the TH17 lineage-specific transcription factor ROR t

(2009) M. Ayyoub et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

(2009) K. S. Voo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

(2008) H. J. P. M. Koenen et al.   BLOOD

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

In vivo equilibrium of proinflammatory IL-17+and regulatory IL-10+Foxp3+RORγt+T cells

(2008) Matthias Lochner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells

(2008) Fuping Zhang et al.   NATURE IMMUNOLOGY

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY