Hepatitis C virus - T-cell responses and viral escape mutations

CD8+ T-Cell Response Promotes Evolution of Hepatitis C Virus Nonstructural Proteins

(2011) Marianne Ruhl et al.   GASTROENTEROLOGY

Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection

(2011) K. Fitzmaurice et al.   GUT

Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion

(2011) Danijela Petrovic et al.   HEPATOLOGY

Constrained Pattern of Viral Evolution in Acute and Early HCV Infection Limits Viral Plasticity

(2011) Katja Pfafferott et al.   PLoS One

Distinct CD4+CD8+ Double-Positive T Cells in the Blood and Liver of Patients during Chronic Hepatitis B and C

(2011) Michelina Nascimbeni et al.   PLoS One

Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection

(2011) M. M. Dring et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The resistance mutation R155K in the NS3/4A protease of hepatitis C virus also leads the virus to escape from HLA-A*68-restricted CD8 T cells

(2010) Shadi Salloum et al.   ANTIVIRAL RESEARCH

Spontaneous Control of HCV Is Associated With Expression of HLA-B*57 and Preservation of Targeted Epitopes

(2010) Arthur Y. Kim et al.   GASTROENTEROLOGY

Virological footprint of CD4+ T-cell responses during chronic hepatitis C virus infection

(2010) V. M. Fleming et al.   JOURNAL OF GENERAL VIROLOGY

Selection-driven immune escape is not a significant factor in the failure of CD4 T cell responses in persistent hepatitis C virus infection

(2009) Michael J. Fuller et al.   HEPATOLOGY

Analysis of CD8+ T-Cell–Mediated Inhibition of Hepatitis C Virus Replication Using a Novel Immunological Model

(2008) Juandy Jo et al.   GASTROENTEROLOGY

Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection

(2008) Christoph Neumann-Haefelin et al.   HEPATOLOGY

Analysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population Level

(2008) C. Neumann-Haefelin et al.   JOURNAL OF VIROLOGY

Escape from HLA-B*08-Restricted CD8 T Cells by Hepatitis C Virus Is Associated with Fitness Costs

(2008) S. Salloum et al.   JOURNAL OF VIROLOGY

Stable Cytotoxic T Cell Escape Mutation in Hepatitis C Virus Is Linked to Maintenance of Viral Fitness

(2008) Luke Uebelhoer et al.   PLoS Pathogens